diff --git a/src/Grpc.Auth/Grpc.Auth.csproj b/src/Grpc.Auth/Grpc.Auth.csproj
index 8edcfcf4f..af058881c 100755
--- a/src/Grpc.Auth/Grpc.Auth.csproj
+++ b/src/Grpc.Auth/Grpc.Auth.csproj
@@ -5,7 +5,7 @@
 
     <IsGrpcPublishedPackage>true</IsGrpcPublishedPackage>
     <GenerateDocumentationFile>true</GenerateDocumentationFile>
-    <TargetFrameworks>net462;netstandard1.5;netstandard2.0</TargetFrameworks>
+    <TargetFrameworks>net462;netstandard2.0</TargetFrameworks>
     <PackageReadmeFile>README.md</PackageReadmeFile>
   </PropertyGroup>
 
diff --git a/src/Grpc.Core.Api/Grpc.Core.Api.csproj b/src/Grpc.Core.Api/Grpc.Core.Api.csproj
index 6cf865ff7..bb6756d1e 100755
--- a/src/Grpc.Core.Api/Grpc.Core.Api.csproj
+++ b/src/Grpc.Core.Api/Grpc.Core.Api.csproj
@@ -5,7 +5,7 @@
 
     <IsGrpcPublishedPackage>true</IsGrpcPublishedPackage>
     <GenerateDocumentationFile>true</GenerateDocumentationFile>
-    <TargetFrameworks>net462;netstandard1.5;netstandard2.0;netstandard2.1</TargetFrameworks>
+    <TargetFrameworks>net462;netstandard2.0;netstandard2.1</TargetFrameworks>
     <PackageReadmeFile>README.md</PackageReadmeFile>
 
     <AllowUnsafeBlocks>true</AllowUnsafeBlocks>
diff --git a/src/Grpc.Core.Api/Internal/ClientDebuggerHelpers.cs b/src/Grpc.Core.Api/Internal/ClientDebuggerHelpers.cs
index f309fd8ce..3ca7b0dba 100644
--- a/src/Grpc.Core.Api/Internal/ClientDebuggerHelpers.cs
+++ b/src/Grpc.Core.Api/Internal/ClientDebuggerHelpers.cs
@@ -25,11 +25,7 @@ namespace Grpc.Core.Internal;
 
 internal static class ClientDebuggerHelpers
 {
-#if NETSTANDARD1_5
-    private static TypeInfo? GetParentType(Type clientType)
-#else
     private static Type? GetParentType(Type clientType)
-#endif
     {
         // Attempt to get the parent type for a generated client.
         // A generated client is always nested inside a static type that contains information about the client.
@@ -48,11 +44,7 @@ internal static class ClientDebuggerHelpers
             return null;
         }
 
-#if NETSTANDARD1_5
-        var parentType = clientType.DeclaringType.GetTypeInfo();
-#else
         var parentType = clientType.DeclaringType;
-#endif
         // Check parent type is static. A C# static type is sealed and abstract.
         if (parentType == null || (!parentType.IsSealed && !parentType.IsAbstract))
         {
@@ -101,10 +93,6 @@ internal static class ClientDebuggerHelpers
         return methods;
 
         static bool IsMethodField(FieldInfo field) =>
-#if NETSTANDARD1_5
-            typeof(IMethod).GetTypeInfo().IsAssignableFrom(field.FieldType);
-#else
             typeof(IMethod).IsAssignableFrom(field.FieldType);
-#endif
     }
 }
diff --git a/src/Grpc.HealthCheck/Grpc.HealthCheck.csproj b/src/Grpc.HealthCheck/Grpc.HealthCheck.csproj
index c6a40f099..d3e02fc34 100755
--- a/src/Grpc.HealthCheck/Grpc.HealthCheck.csproj
+++ b/src/Grpc.HealthCheck/Grpc.HealthCheck.csproj
@@ -5,7 +5,7 @@
 
     <IsGrpcPublishedPackage>true</IsGrpcPublishedPackage>
     <GenerateDocumentationFile>true</GenerateDocumentationFile>
-    <TargetFrameworks>net462;netstandard1.5;netstandard2.0</TargetFrameworks>
+    <TargetFrameworks>net462;netstandard2.0</TargetFrameworks>
     <PackageReadmeFile>README.md</PackageReadmeFile>
   </PropertyGroup>
 
diff --git a/src/Grpc.Reflection/Grpc.Reflection.csproj b/src/Grpc.Reflection/Grpc.Reflection.csproj
index 0a52e1642..63b23d665 100755
--- a/src/Grpc.Reflection/Grpc.Reflection.csproj
+++ b/src/Grpc.Reflection/Grpc.Reflection.csproj
@@ -5,7 +5,7 @@
 
     <IsGrpcPublishedPackage>true</IsGrpcPublishedPackage>
     <GenerateDocumentationFile>true</GenerateDocumentationFile>
-    <TargetFrameworks>net462;netstandard1.5;netstandard2.0</TargetFrameworks>
+    <TargetFrameworks>net462;netstandard2.0</TargetFrameworks>
     <PackageReadmeFile>README.md</PackageReadmeFile>
   </PropertyGroup>