diff --git a/.drone/drone.yml b/.drone/drone.yml
index e66f34b0678c..3b508a8869ec 100644
--- a/.drone/drone.yml
+++ b/.drone/drone.yml
@@ -54,48 +54,6 @@ steps:
 depends_on:
   - Lint
 
----
-kind: pipeline
-type: docker
-name: E2E
-platform:
-  os: linux
-  arch: amd64
-trigger:
-  event:
-    - push
-    - pull_request
-    - tag
-  ref:
-    - refs/heads/main
-    - refs/pull/*/head
-    - refs/tags/**
-steps:
-  - name: lint
-    image: golangci/golangci-lint:v1.43.0
-    commands:
-      - make DRONE=true e2e/lint
-  - name: test
-    image: docker
-    volumes:
-      - name: docker
-        path: /var/run/docker.sock
-    commands:
-      - apk update && apk add make gcc libc-dev bash wget git
-      - mkdir -p /usr/local/go/bin
-      - wget -q https://golang.org/dl/go1.17.5.linux-amd64.tar.gz
-      - tar -C /usr/local -xzf go1.17.5.linux-amd64.tar.gz
-      - rm go1.17.5.linux-amd64.tar.gz
-      - export PATH=$PATH:/usr/local/go/bin
-      - make E2E_K8S_USE_DOCKER_NETWORK=1 DRONE=true e2e/test
-
-depends_on:
-  - Test
-
-volumes:
-  - name: docker
-    host:
-      path: /var/run/docker.sock
 
 ---
 kind: pipeline
@@ -122,7 +80,6 @@ steps:
       - make DRONE=true BUILD_IN_CONTAINER=false dist
 depends_on:
   - Test
-  - E2E
 ---
 kind: pipeline
 type: docker
@@ -285,6 +242,6 @@ get:
   name: pat
 ---
 kind: signature
-hmac: 8ad4ba391594eb265cb8737d77509da2633e5a19f889b126f01fa78f51358715
+hmac: 11038ae4592a13955388dff643b35bb1f07e53a659cdca946e863c9f2ac77066
 
 ...
diff --git a/CHANGELOG.md b/CHANGELOG.md
index dcc49aca5967..38aee5d014e3 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -1,5 +1,7 @@
 # Main (unreleased)
 
+# v0.22.0 (2022-01-13)
+
 This release has deprecations. Please read [DEPRECATION] entries and consult
 the [upgrade guide](https://github.com/grafana/agent/blob/main/docs/upgrade-guide/_index.md)
 for detailed information.
diff --git a/docs/configuration/integrations/node-exporter-config.md b/docs/configuration/integrations/node-exporter-config.md
index 7399525940e2..6ce79fbab36a 100644
--- a/docs/configuration/integrations/node-exporter-config.md
+++ b/docs/configuration/integrations/node-exporter-config.md
@@ -26,7 +26,7 @@ docker run \
   -v "/proc:/host/proc:ro,rslave" \
   -v /tmp/agent:/etc/agent \
   -v /path/to/config.yaml:/etc/agent-config/agent.yaml \
-  grafana/agent:v0.21.2 \
+  grafana/agent:v0.22.0 \
   --config.file=/etc/agent-config/agent.yaml
 ```
 
@@ -66,7 +66,7 @@ metadata:
   name: agent
 spec:
   containers:
-  - image: grafana/agent:v0.21.2
+  - image: grafana/agent:v0.22.0
     name: agent
     args:
     - --config.file=/etc/agent-config/agent.yaml
diff --git a/docs/configuration/integrations/process-exporter-config.md b/docs/configuration/integrations/process-exporter-config.md
index d5e428841a54..55b6d35c1f31 100644
--- a/docs/configuration/integrations/process-exporter-config.md
+++ b/docs/configuration/integrations/process-exporter-config.md
@@ -18,7 +18,7 @@ docker run \
   -v "/proc:/proc:ro" \
   -v /tmp/agent:/etc/agent \
   -v /path/to/config.yaml:/etc/agent-config/agent.yaml \
-  grafana/agent:v0.21.2 \
+  grafana/agent:v0.22.0 \
   --config.file=/etc/agent-config/agent.yaml
 ```
 
@@ -35,7 +35,7 @@ metadata:
   name: agent
 spec:
   containers:
-  - image: grafana/agent:v0.21.2
+  - image: grafana/agent:v0.22.0
     name: agent
     args:
     - --config.file=/etc/agent-config/agent.yaml
diff --git a/docs/getting-started/_index.md b/docs/getting-started/_index.md
index e7aead64b57c..686264eab8c8 100644
--- a/docs/getting-started/_index.md
+++ b/docs/getting-started/_index.md
@@ -26,7 +26,7 @@ See the list of [Community Projects](#community-projects) for the community-driv
 docker run \
   -v /tmp/agent:/etc/agent/data \
   -v /path/to/config.yaml:/etc/agent/agent.yaml \
-  grafana/agent:v0.21.2
+  grafana/agent:v0.22.0
 ```
 
 Replace `/tmp/agent` with the folder you wish to store WAL data in. WAL data is
diff --git a/docs/operator/custom-resource-quickstart.md b/docs/operator/custom-resource-quickstart.md
index bfef07d9cb47..084d1b47a06a 100644
--- a/docs/operator/custom-resource-quickstart.md
+++ b/docs/operator/custom-resource-quickstart.md
@@ -43,7 +43,7 @@ metadata:
   labels:
     app: grafana-agent
 spec:
-  image: grafana/agent:v0.21.2
+  image: grafana/agent:v0.22.0
   logLevel: info
   serviceAccountName: grafana-agent
   metrics:
diff --git a/docs/operator/getting-started.md b/docs/operator/getting-started.md
index fe11b9543a92..2438a0846534 100644
--- a/docs/operator/getting-started.md
+++ b/docs/operator/getting-started.md
@@ -72,7 +72,7 @@ spec:
       serviceAccountName: grafana-agent-operator
       containers:
       - name: operator
-        image: grafana/agent-operator:v0.21.2
+        image: grafana/agent-operator:v0.22.0
         args:
         - --kubelet-service=default/kubelet
 ---
diff --git a/docs/upgrade-guide/_index.md b/docs/upgrade-guide/_index.md
index 6b397b852343..7363673ad8b4 100644
--- a/docs/upgrade-guide/_index.md
+++ b/docs/upgrade-guide/_index.md
@@ -12,6 +12,8 @@ releases and how to migrate to newer versions.
 
 These changes will come in a future version.
 
+## v0.22.0
+
 ### `node_exporter` integration deprecated field names
 
 The following field names for the `node_exporter` integration are now deprecated:
diff --git a/pkg/operator/defaults.go b/pkg/operator/defaults.go
index e0189dc0f942..58ee7a517afc 100644
--- a/pkg/operator/defaults.go
+++ b/pkg/operator/defaults.go
@@ -19,6 +19,7 @@ var (
 		"v0.21.0",
 		"v0.21.1",
 		"v0.21.2",
+		"v0.22.0",
 
 		// NOTE(rfratto): when performing an upgrade, add the newest version above instead of changing the existing reference.
 	}
diff --git a/production/README.md b/production/README.md
index 2fe509253e6e..4bbb146d4682 100644
--- a/production/README.md
+++ b/production/README.md
@@ -27,7 +27,7 @@ directory on your host that you want the agent to store its WAL.
 docker run \
   -v /tmp/agent:/etc/agent/data \
   -v /path/to/config.yaml:/etc/agent/agent.yaml \
-  grafana/agent:v0.21.2
+  grafana/agent:v0.22.0
 ```
 
 ## Running the Agent locally
diff --git a/production/grafanacloud-install.sh b/production/grafanacloud-install.sh
index b7acda2ba2c5..c2d07a53eeea 100755
--- a/production/grafanacloud-install.sh
+++ b/production/grafanacloud-install.sh
@@ -50,7 +50,7 @@ PACKAGE_SYSTEM=${PACKAGE_SYSTEM:=}
 #
 # Global constants.
 #
-RELEASE_VERSION="0.21.2"
+RELEASE_VERSION="0.22.0"
 
 RELEASE_URL="https://github.com/grafana/agent/releases/download/v${RELEASE_VERSION}"
 DEB_URL="${RELEASE_URL}/grafana-agent-${RELEASE_VERSION}-1.${ARCH}.deb"
diff --git a/production/kubernetes/agent-bare.yaml b/production/kubernetes/agent-bare.yaml
index cea60c76ba81..2eda70a26a8b 100644
--- a/production/kubernetes/agent-bare.yaml
+++ b/production/kubernetes/agent-bare.yaml
@@ -66,7 +66,7 @@ spec:
           valueFrom:
             fieldRef:
               fieldPath: spec.nodeName
-        image: grafana/agent:v0.21.2
+        image: grafana/agent:v0.22.0
         imagePullPolicy: IfNotPresent
         name: agent
         ports:
diff --git a/production/kubernetes/agent-loki.yaml b/production/kubernetes/agent-loki.yaml
index bd746b2b7b98..cf284912af18 100644
--- a/production/kubernetes/agent-loki.yaml
+++ b/production/kubernetes/agent-loki.yaml
@@ -64,7 +64,7 @@ spec:
           valueFrom:
             fieldRef:
               fieldPath: spec.nodeName
-        image: grafana/agent:v0.21.2
+        image: grafana/agent:v0.22.0
         imagePullPolicy: IfNotPresent
         name: agent
         ports:
diff --git a/production/kubernetes/agent-traces.yaml b/production/kubernetes/agent-traces.yaml
index 51b82f7e5151..3ad3616f1f3a 100644
--- a/production/kubernetes/agent-traces.yaml
+++ b/production/kubernetes/agent-traces.yaml
@@ -109,7 +109,7 @@ spec:
           valueFrom:
             fieldRef:
               fieldPath: spec.nodeName
-        image: grafana/agent:v0.21.2
+        image: grafana/agent:v0.22.0
         imagePullPolicy: IfNotPresent
         name: agent
         ports:
diff --git a/production/kubernetes/build/lib/version.libsonnet b/production/kubernetes/build/lib/version.libsonnet
index 47c428aa1220..24f9f8cd67a2 100644
--- a/production/kubernetes/build/lib/version.libsonnet
+++ b/production/kubernetes/build/lib/version.libsonnet
@@ -1 +1 @@
-'grafana/agent:v0.21.2'
+'grafana/agent:v0.22.0'
diff --git a/production/kubernetes/install-bare.sh b/production/kubernetes/install-bare.sh
index cfcef950a1ce..e113a84dfbc1 100644
--- a/production/kubernetes/install-bare.sh
+++ b/production/kubernetes/install-bare.sh
@@ -25,7 +25,7 @@ check_installed() {
 check_installed curl
 check_installed envsubst
 
-MANIFEST_BRANCH=v0.21.2
+MANIFEST_BRANCH=v0.22.0
 MANIFEST_URL=${MANIFEST_URL:-https://raw.githubusercontent.com/grafana/agent/${MANIFEST_BRANCH}/production/kubernetes/agent-bare.yaml}
 NAMESPACE=${NAMESPACE:-default}
 
diff --git a/production/tanka/grafana-agent/v1/main.libsonnet b/production/tanka/grafana-agent/v1/main.libsonnet
index cda3bffd1942..088e09ba87ca 100644
--- a/production/tanka/grafana-agent/v1/main.libsonnet
+++ b/production/tanka/grafana-agent/v1/main.libsonnet
@@ -15,8 +15,8 @@ local service = k.core.v1.service;
 (import './lib/traces.libsonnet') +
 {
   _images:: {
-    agent: 'grafana/agent:v0.21.2',
-    agentctl: 'grafana/agentctl:v0.21.2',
+    agent: 'grafana/agent:v0.22.0',
+    agentctl: 'grafana/agentctl:v0.22.0',
   },
 
   // new creates a new DaemonSet deployment of the grafana-agent. By default,
diff --git a/production/tanka/grafana-agent/v2/internal/base.libsonnet b/production/tanka/grafana-agent/v2/internal/base.libsonnet
index c07b012d978d..48845de718a0 100644
--- a/production/tanka/grafana-agent/v2/internal/base.libsonnet
+++ b/production/tanka/grafana-agent/v2/internal/base.libsonnet
@@ -10,8 +10,8 @@ function(name='grafana-agent', namespace='') {
   local this = self,
 
   _images:: {
-    agent: 'grafana/agent:v0.21.2',
-    agentctl: 'grafana/agentctl:v0.21.2',
+    agent: 'grafana/agent:v0.22.0',
+    agentctl: 'grafana/agentctl:v0.22.0',
   },
   _config:: {
     name: name,
diff --git a/production/tanka/grafana-agent/v2/internal/syncer.libsonnet b/production/tanka/grafana-agent/v2/internal/syncer.libsonnet
index a90672591d68..15c4fc8bf4b8 100644
--- a/production/tanka/grafana-agent/v2/internal/syncer.libsonnet
+++ b/production/tanka/grafana-agent/v2/internal/syncer.libsonnet
@@ -14,7 +14,7 @@ function(
 ) {
   local _config = {
     api: error 'api must be set',
-    image: 'grafana/agentctl:v0.21.2',
+    image: 'grafana/agentctl:v0.22.0',
     schedule: '*/5 * * * *',
     configs: [],
   } + config,