diff --git a/packages/react-dom-bindings/src/server/fizz-instruction-set/ReactDOMFizzInstructionSetInlineCodeStrings.js b/packages/react-dom-bindings/src/server/fizz-instruction-set/ReactDOMFizzInstructionSetInlineCodeStrings.js
index cd7ecbbb9b022..8becb67c2ab38 100644
--- a/packages/react-dom-bindings/src/server/fizz-instruction-set/ReactDOMFizzInstructionSetInlineCodeStrings.js
+++ b/packages/react-dom-bindings/src/server/fizz-instruction-set/ReactDOMFizzInstructionSetInlineCodeStrings.js
@@ -4,7 +4,7 @@
 export const clientRenderBoundary =
   '$RX=function(b,c,d,e,f){var a=document.getElementById(b);a&&(b=a.previousSibling,b.data="$!",a=a.dataset,c&&(a.dgst=c),d&&(a.msg=d),e&&(a.stck=e),f&&(a.cstck=f),b._reactRetry&&b._reactRetry())};';
 export const completeBoundary =
-  '$RC=function(b,d,e){d=document.getElementById(d);d.parentNode.removeChild(d);var a=document.getElementById(b);if(a){b=a.previousSibling;if(e)b.data="$!",a.setAttribute("data-dgst",e);else{e=b.parentNode;a=b.nextSibling;var f=0;do{if(a&&8===a.nodeType){var c=a.data;if("/$"===c||"/&"===c)if(0===f)break;else f--;else"$"!==c&&"$?"!==c&&"$!"!==c&&"&"!==c||f++}c=a.nextSibling;e.removeChild(a);a=c}while(a);for(;d.firstChild;)e.insertBefore(d.firstChild,a);b.data="$"}b._reactRetry&&b._reactRetry()}};';
+  '$RC=function(b,d,e){if(d=document.getElementById(d)){d.parentNode.removeChild(d);var a=document.getElementById(b);if(a){b=a.previousSibling;if(e)b.data="$!",a.setAttribute("data-dgst",e);else{e=b.parentNode;a=b.nextSibling;var f=0;do{if(a&&8===a.nodeType){var c=a.data;if("/$"===c||"/&"===c)if(0===f)break;else f--;else"$"!==c&&"$?"!==c&&"$!"!==c&&"&"!==c||f++}c=a.nextSibling;e.removeChild(a);a=c}while(a);for(;d.firstChild;)e.insertBefore(d.firstChild,a);b.data="$"}b._reactRetry&&b._reactRetry()}}};';
 export const completeBoundaryWithStyles =
   '$RM=new Map;\n$RR=function(t,u,y){function v(n){this._p=null;n()}for(var w=$RC,p=$RM,q=new Map,r=document,g,b,h=r.querySelectorAll("link[data-precedence],style[data-precedence]"),x=[],k=0;b=h[k++];)"not all"===b.getAttribute("media")?x.push(b):("LINK"===b.tagName&&p.set(b.getAttribute("href"),b),q.set(b.dataset.precedence,g=b));b=0;h=[];var l,a;for(k=!0;;){if(k){var e=y[b++];if(!e){k=!1;b=0;continue}var c=!1,m=0;var d=e[m++];if(a=p.get(d)){var f=a._p;c=!0}else{a=r.createElement("link");a.href=\nd;a.rel="stylesheet";for(a.dataset.precedence=l=e[m++];f=e[m++];)a.setAttribute(f,e[m++]);f=a._p=new Promise(function(n,z){a.onload=v.bind(a,n);a.onerror=v.bind(a,z)});p.set(d,a)}d=a.getAttribute("media");!f||d&&!matchMedia(d).matches||h.push(f);if(c)continue}else{a=x[b++];if(!a)break;l=a.getAttribute("data-precedence");a.removeAttribute("media")}c=q.get(l)||g;c===g&&(g=a);q.set(l,a);c?c.parentNode.insertBefore(a,c.nextSibling):(c=r.head,c.insertBefore(a,c.firstChild))}Promise.all(h).then(w.bind(null,\nt,u,""),w.bind(null,t,u,"Resource failed to load"))};';
 export const completeSegment =
diff --git a/packages/react-dom-bindings/src/server/fizz-instruction-set/ReactDOMFizzInstructionSetShared.js b/packages/react-dom-bindings/src/server/fizz-instruction-set/ReactDOMFizzInstructionSetShared.js
index 044a547492889..8fd56b3df9579 100644
--- a/packages/react-dom-bindings/src/server/fizz-instruction-set/ReactDOMFizzInstructionSetShared.js
+++ b/packages/react-dom-bindings/src/server/fizz-instruction-set/ReactDOMFizzInstructionSetShared.js
@@ -49,6 +49,12 @@ export function clientRenderBoundary(
 
 export function completeBoundary(suspenseBoundaryID, contentID, errorDigest) {
   const contentNode = document.getElementById(contentID);
+  if (!contentNode) {
+    // If the client has failed hydration we may have already deleted the streaming
+    // segments. The server may also have emitted a complete instruction but cancelled
+    // the segment. Regardless we can ignore this case.
+    return;
+  }
   // We'll detach the content node so that regardless of what happens next we don't leave in the tree.
   // This might also help by not causing recalcing each time we move a child from here to the target.
   contentNode.parentNode.removeChild(contentNode);