diff --git a/Cargo.lock b/Cargo.lock
index ec3a5ca24e4..39d9a9f20fe 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -809,12 +809,11 @@ dependencies = [
 
 [[package]]
 name = "pyo3"
-version = "0.24.2"
+version = "0.25.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "e5203598f366b11a02b13aa20cab591229ff0a89fd121a308a5df751d5fc9219"
+checksum = "8970a78afe0628a3e3430376fc5fd76b6b45c4d43360ffd6cdd40bdde72b682a"
 dependencies = [
  "anyhow",
- "cfg-if",
  "indoc",
  "libc",
  "memoffset",
@@ -828,9 +827,9 @@ dependencies = [
 
 [[package]]
 name = "pyo3-build-config"
-version = "0.24.2"
+version = "0.25.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "99636d423fa2ca130fa5acde3059308006d46f98caac629418e53f7ebb1e9999"
+checksum = "458eb0c55e7ece017adeba38f2248ff3ac615e53660d7c71a238d7d2a01c7598"
 dependencies = [
  "once_cell",
  "target-lexicon",
@@ -838,9 +837,9 @@ dependencies = [
 
 [[package]]
 name = "pyo3-ffi"
-version = "0.24.2"
+version = "0.25.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "78f9cf92ba9c409279bc3305b5409d90db2d2c22392d443a87df3a1adad59e33"
+checksum = "7114fe5457c61b276ab77c5055f206295b812608083644a5c5b2640c3102565c"
 dependencies = [
  "libc",
  "pyo3-build-config",
@@ -859,9 +858,9 @@ dependencies = [
 
 [[package]]
 name = "pyo3-macros"
-version = "0.24.2"
+version = "0.25.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "0b999cb1a6ce21f9a6b147dcf1be9ffedf02e0043aec74dc390f3007047cecd9"
+checksum = "a8725c0a622b374d6cb051d11a0983786448f7785336139c3c94f5aa6bef7e50"
 dependencies = [
  "proc-macro2",
  "pyo3-macros-backend",
@@ -871,9 +870,9 @@ dependencies = [
 
 [[package]]
 name = "pyo3-macros-backend"
-version = "0.24.2"
+version = "0.25.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "822ece1c7e1012745607d5cf0bcb2874769f0f7cb34c4cde03b9358eb9ef911a"
+checksum = "4109984c22491085343c05b0dbc54ddc405c3cf7b4374fc533f5c3313a572ccc"
 dependencies = [
  "heck",
  "proc-macro2",
@@ -884,9 +883,9 @@ dependencies = [
 
 [[package]]
 name = "pythonize"
-version = "0.24.0"
+version = "0.25.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "d5bcac0d0b71821f0d69e42654f1e15e5c94b85196446c4de9588951a2117e7b"
+checksum = "597907139a488b22573158793aa7539df36ae863eba300c75f3a0d65fc475e27"
 dependencies = [
  "pyo3",
  "serde",
diff --git a/changelog.d/18578.misc b/changelog.d/18578.misc
new file mode 100644
index 00000000000..cafba777226
--- /dev/null
+++ b/changelog.d/18578.misc
@@ -0,0 +1 @@
+Update PyO3 to version 0.25.
diff --git a/rust/Cargo.toml b/rust/Cargo.toml
index 446db1bcf11..3a47f7ddf75 100644
--- a/rust/Cargo.toml
+++ b/rust/Cargo.toml
@@ -30,14 +30,14 @@ http = "1.1.0"
 lazy_static = "1.4.0"
 log = "0.4.17"
 mime = "0.3.17"
-pyo3 = { version = "0.24.2", features = [
+pyo3 = { version = "0.25.1", features = [
     "macros",
     "anyhow",
     "abi3",
     "abi3-py39",
 ] }
-pyo3-log = "0.12.3"
-pythonize = "0.24.0"
+pyo3-log = "0.12.4"
+pythonize = "0.25.0"
 regex = "1.6.0"
 sha2 = "0.10.8"
 serde = { version = "1.0.144", features = ["derive"] }