diff --git a/packages/eui/changelogs/upcoming/9282.md b/packages/eui/changelogs/upcoming/9282.md
new file mode 100644
index 00000000000..4e42e8c3ad1
--- /dev/null
+++ b/packages/eui/changelogs/upcoming/9282.md
@@ -0,0 +1,4 @@
+**Accessibility**
+
+- Improved the accessibility of `EuiDataGrid`s column selector drag handle buttons by ensuring distinctive labels
+
diff --git a/packages/eui/src/components/datagrid/controls/__snapshots__/column_selector.test.tsx.snap b/packages/eui/src/components/datagrid/controls/__snapshots__/column_selector.test.tsx.snap
index bc3d63f1d94..fa23b57319d 100644
--- a/packages/eui/src/components/datagrid/controls/__snapshots__/column_selector.test.tsx.snap
+++ b/packages/eui/src/components/datagrid/controls/__snapshots__/column_selector.test.tsx.snap
@@ -147,7 +147,7 @@ exports[`useDataGridColumnSelector columnSelector renders a toolbar button/popov
                   </div>
                   <div
                     aria-describedby="rfd-hidden-text-:r0:-hidden-text-:r1:"
-                    aria-label="Drag handle"
+                    aria-label="columnA drag handle"
                     class="euiFlexItem emotion-euiFlexItem-growZero"
                     data-rfd-drag-handle-context-id=":r0:"
                     data-rfd-drag-handle-draggable-id="columnA"
@@ -220,7 +220,7 @@ exports[`useDataGridColumnSelector columnSelector renders a toolbar button/popov
                   </div>
                   <div
                     aria-describedby="rfd-hidden-text-:r0:-hidden-text-:r1:"
-                    aria-label="Drag handle"
+                    aria-label="columnB drag handle"
                     class="euiFlexItem emotion-euiFlexItem-growZero"
                     data-rfd-drag-handle-context-id=":r0:"
                     data-rfd-drag-handle-draggable-id="columnB"
diff --git a/packages/eui/src/components/datagrid/controls/column_selector.test.tsx b/packages/eui/src/components/datagrid/controls/column_selector.test.tsx
index 75ec077a7fa..9d2e844d8e9 100644
--- a/packages/eui/src/components/datagrid/controls/column_selector.test.tsx
+++ b/packages/eui/src/components/datagrid/controls/column_selector.test.tsx
@@ -131,7 +131,7 @@ describe('useDataGridColumnSelector', () => {
         );
         fireEvent.click(getByTestSubject('dataGridColumnSelectorButton'));
         waitForEuiPopoverOpen();
-        const getDragHandles = () => getAllByLabelText('Drag handle');
+        const getDragHandles = () => getAllByLabelText(/drag handle/);
 
         const columnA = getDragHandles()[0]!;
         expect(columnA).toHaveAttribute(
diff --git a/packages/eui/src/components/datagrid/controls/column_selector.tsx b/packages/eui/src/components/datagrid/controls/column_selector.tsx
index 51a59de176f..c50c473a495 100644
--- a/packages/eui/src/components/datagrid/controls/column_selector.tsx
+++ b/packages/eui/src/components/datagrid/controls/column_selector.tsx
@@ -163,7 +163,7 @@ export const useDataGridColumnSelector = (
   const isDragEnabled = allowColumnReorder && columnSearchText.length === 0; // only allow drag-and-drop when not filtering columns
   const dragHandleAriaLabel = useEuiI18n(
     'euiColumnSelector.dragHandleAriaLabel',
-    'Drag handle'
+    'drag handle'
   );
 
   const orderedVisibleColumns = useMemo(
@@ -235,84 +235,91 @@ export const useDataGridColumnSelector = (
             css={styles.euiDataGridColumnSelector}
           >
             <>
-              {filteredColumns.map((id, index) => (
-                <EuiDraggable
-                  key={id}
-                  draggableId={id}
-                  index={index}
-                  isDragDisabled={!isDragEnabled}
-                  hasInteractiveChildren
-                  customDragHandle
-                  usePortal
-                >
-                  {(provided, state) => (
-                    <div
-                      css={styles.euiDataGridColumnSelector__item}
-                      className={classNames('euiDataGridColumnSelector__item', {
-                        'euiDataGridColumnSelector__item-isDragging':
-                          state.isDragging,
-                      })}
-                      data-test-subj={`dataGridColumnSelectorColumnItem-${id}`}
-                    >
-                      <EuiFlexGroup
-                        responsive={false}
-                        gutterSize="s"
-                        alignItems="center"
-                      >
-                        {allowColumnHiding && (
-                          <EuiFlexItem grow={false}>
-                            <EuiSwitch
-                              name={id}
-                              label={displayValues[id] || id}
-                              showLabel={false}
-                              checked={visibleColumnIds.has(id)}
-                              mini
-                              onChange={(event) => {
-                                const {
-                                  target: { checked },
-                                } = event;
-                                const nextVisibleColumns = sortedColumns.filter(
-                                  (columnId) =>
-                                    checked
-                                      ? visibleColumnIds.has(columnId) ||
-                                        id === columnId
-                                      : visibleColumnIds.has(columnId) &&
-                                        id !== columnId
-                                );
-                                setVisibleColumns(nextVisibleColumns);
-                              }}
-                              data-test-subj={`dataGridColumnSelectorToggleColumnVisibility-${id}`}
-                            />
-                          </EuiFlexItem>
+              {filteredColumns.map((id, index) => {
+                const label = displayValues[id] || id;
+
+                return (
+                  <EuiDraggable
+                    key={id}
+                    draggableId={id}
+                    index={index}
+                    isDragDisabled={!isDragEnabled}
+                    hasInteractiveChildren
+                    customDragHandle
+                    usePortal
+                  >
+                    {(provided, state) => (
+                      <div
+                        css={styles.euiDataGridColumnSelector__item}
+                        className={classNames(
+                          'euiDataGridColumnSelector__item',
+                          {
+                            'euiDataGridColumnSelector__item-isDragging':
+                              state.isDragging,
+                          }
                         )}
-                        <EuiFlexItem
-                          // This extra column name flex item affords the column more grabbable real estate
-                          // for mouse users, while hiding repetition for keyboard/screen reader users
-                          {...provided.dragHandleProps}
-                          aria-hidden
-                          tabIndex={-1}
+                        data-test-subj={`dataGridColumnSelectorColumnItem-${id}`}
+                      >
+                        <EuiFlexGroup
+                          responsive={false}
+                          gutterSize="s"
+                          alignItems="center"
                         >
-                          <EuiText
-                            size="xs"
-                            className="euiDataGridColumnSelector__itemLabel"
-                          >
-                            {displayValues[id] || id}
-                          </EuiText>
-                        </EuiFlexItem>
-                        {isDragEnabled && (
+                          {allowColumnHiding && (
+                            <EuiFlexItem grow={false}>
+                              <EuiSwitch
+                                name={id}
+                                label={label}
+                                showLabel={false}
+                                checked={visibleColumnIds.has(id)}
+                                mini
+                                onChange={(event) => {
+                                  const {
+                                    target: { checked },
+                                  } = event;
+                                  const nextVisibleColumns =
+                                    sortedColumns.filter((columnId) =>
+                                      checked
+                                        ? visibleColumnIds.has(columnId) ||
+                                          id === columnId
+                                        : visibleColumnIds.has(columnId) &&
+                                          id !== columnId
+                                    );
+                                  setVisibleColumns(nextVisibleColumns);
+                                }}
+                                data-test-subj={`dataGridColumnSelectorToggleColumnVisibility-${id}`}
+                              />
+                            </EuiFlexItem>
+                          )}
                           <EuiFlexItem
-                            grow={false}
+                            // This extra column name flex item affords the column more grabbable real estate
+                            // for mouse users, while hiding repetition for keyboard/screen reader users
                             {...provided.dragHandleProps}
-                            aria-label={dragHandleAriaLabel}
+                            aria-hidden
+                            tabIndex={-1}
                           >
-                            <EuiIcon type="grab" color="subdued" />
+                            <EuiText
+                              size="xs"
+                              className="euiDataGridColumnSelector__itemLabel"
+                            >
+                              {label}
+                            </EuiText>
                           </EuiFlexItem>
-                        )}
-                      </EuiFlexGroup>
-                    </div>
-                  )}
-                </EuiDraggable>
-              ))}
+                          {isDragEnabled && (
+                            <EuiFlexItem
+                              grow={false}
+                              {...provided.dragHandleProps}
+                              aria-label={`${label} ${dragHandleAriaLabel}`}
+                            >
+                              <EuiIcon type="grab" color="subdued" />
+                            </EuiFlexItem>
+                          )}
+                        </EuiFlexGroup>
+                      </div>
+                    )}
+                  </EuiDraggable>
+                );
+              })}
             </>
           </EuiDroppable>
         </EuiDragDropContext>