diff --git a/packages/eui-theme-borealis/changelogs/upcoming/9044.md b/packages/eui-theme-borealis/changelogs/upcoming/9044.md
new file mode 100644
index 00000000000..80041185718
--- /dev/null
+++ b/packages/eui-theme-borealis/changelogs/upcoming/9044.md
@@ -0,0 +1 @@
+Added theme defaults for `spacing` of `emptyPrompt` content
\ No newline at end of file
diff --git a/packages/eui-theme-borealis/src/eui_theme_borealis_dark.json b/packages/eui-theme-borealis/src/eui_theme_borealis_dark.json
index ed01cd7edb3..6f5555c55ae 100644
--- a/packages/eui-theme-borealis/src/eui_theme_borealis_dark.json
+++ b/packages/eui-theme-borealis/src/eui_theme_borealis_dark.json
@@ -423,5 +423,12 @@
   "euiColorBorderStrongWarning": "#FACB3D",
   "euiColorBorderStrongRisk": "#FC8544",
   "euiColorBorderStrongDanger": "#F6726A",
-  "euiColorBorderStrongText": "#8E9FBC"
+  "euiColorBorderStrongText": "#8E9FBC",
+  "spacing": {
+    "emptyPrompt": {
+      "titleBodySpacing": "s",
+      "bodyActionsSpacing": "m",
+      "paddingSize": "m"
+    }
+  }
 }
diff --git a/packages/eui-theme-borealis/src/eui_theme_borealis_light.json b/packages/eui-theme-borealis/src/eui_theme_borealis_light.json
index 941b63776a6..5ea31808114 100644
--- a/packages/eui-theme-borealis/src/eui_theme_borealis_light.json
+++ b/packages/eui-theme-borealis/src/eui_theme_borealis_light.json
@@ -423,5 +423,12 @@
   "euiColorBorderStrongWarning": "#966B03",
   "euiColorBorderStrongRisk": "#C24411",
   "euiColorBorderStrongDanger": "#C61E25",
-  "euiColorBorderStrongText": "#5A6D8C"
+  "euiColorBorderStrongText": "#5A6D8C",
+  "spacing": {
+    "emptyPrompt": {
+      "titleBodySpacing": "s",
+      "bodyActionsSpacing": "m",
+      "paddingSize": "m"
+    }
+  }
 }
diff --git a/packages/eui-theme-borealis/src/index.ts b/packages/eui-theme-borealis/src/index.ts
index 078c739583c..38165eaa713 100644
--- a/packages/eui-theme-borealis/src/index.ts
+++ b/packages/eui-theme-borealis/src/index.ts
@@ -17,6 +17,7 @@ import { levels } from './variables/_levels';
 import { font } from './variables/_typography';
 import { focus } from './variables/_states';
 import { components } from './variables/_components';
+import { spacing } from './variables/_spacing';
 import { overrides } from './variables/_overrides';
 
 import { colorVisLight } from './variables/colors/_colors_vis_light';
@@ -26,7 +27,7 @@ export { colorVisLight as colorVis, colorVisLight, colorVisDark };
 
 export const EUI_THEME_BOREALIS_KEY = 'EUI_THEME_BOREALIS';
 
-export const euiThemeBorealis: EuiThemeShape = {
+export const euiThemeBorealis: EuiThemeShape & { spacing: typeof spacing } = {
   colors,
   base,
   size,
@@ -37,6 +38,7 @@ export const euiThemeBorealis: EuiThemeShape = {
   levels,
   focus,
   components,
+  spacing,
   flags: {
     hasGlobalFocusColor: true,
     hasVisColorAdjustment: false,
diff --git a/packages/eui-theme-borealis/src/variables/_spacing.ts b/packages/eui-theme-borealis/src/variables/_spacing.ts
new file mode 100644
index 00000000000..2d7b0077dc7
--- /dev/null
+++ b/packages/eui-theme-borealis/src/variables/_spacing.ts
@@ -0,0 +1,19 @@
+/*
+ * Copyright Elasticsearch B.V. and/or licensed to Elasticsearch B.V. under one
+ * or more contributor license agreements. Licensed under the Elastic License
+ * 2.0 and the Server Side Public License, v 1; you may not use this file except
+ * in compliance with, at your election, the Elastic License 2.0 or the Server
+ * Side Public License, v 1.
+ */
+
+// Component-specific spacing configurations
+export const emptyPromptSpacing = {
+  titleBodySpacing: 's',    // Reduced from default 'm' (16px → 8px)
+  bodyActionsSpacing: 'm',  // Reduced from default 'l' (24px → 16px)
+  paddingSize: 'm',         // Reduced from default 'l' (24px → 16px)
+};
+
+// Main spacing export (following the same pattern as _typography.ts)
+export const spacing = {
+  emptyPrompt: emptyPromptSpacing,
+};
diff --git a/packages/eui/.loki/reference/chrome_desktop_Display_EuiEmptyPrompt_Page_Template.png b/packages/eui/.loki/reference/chrome_desktop_Display_EuiEmptyPrompt_Page_Template.png
index f72fcb20e10..17d8bceee0c 100644
Binary files a/packages/eui/.loki/reference/chrome_desktop_Display_EuiEmptyPrompt_Page_Template.png and b/packages/eui/.loki/reference/chrome_desktop_Display_EuiEmptyPrompt_Page_Template.png differ
diff --git a/packages/eui/changelogs/upcoming/9044.md b/packages/eui/changelogs/upcoming/9044.md
new file mode 100644
index 00000000000..4de6a536e6a
--- /dev/null
+++ b/packages/eui/changelogs/upcoming/9044.md
@@ -0,0 +1 @@
+- Added `emptyPromptSpacing` theme configuration for `EuiEmptyPrompt`
\ No newline at end of file
diff --git a/packages/eui/src/components/empty_prompt/__snapshots__/empty_prompt.test.tsx.snap b/packages/eui/src/components/empty_prompt/__snapshots__/empty_prompt.test.tsx.snap
index 847de3a3ef2..234a61ad663 100644
--- a/packages/eui/src/components/empty_prompt/__snapshots__/empty_prompt.test.tsx.snap
+++ b/packages/eui/src/components/empty_prompt/__snapshots__/empty_prompt.test.tsx.snap
@@ -7,7 +7,7 @@ exports[`EuiEmptyPrompt is rendered 1`] = `
   data-test-subj="test subject string"
 >
   <div
-    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-l"
+    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-m"
   >
     <div
       class="euiEmptyPrompt__icon emotion-euiEmptyPrompt__icon-vertical"
@@ -26,7 +26,7 @@ exports[`EuiEmptyPrompt is rendered 1`] = `
         Title
       </h2>
       <div
-        class="euiSpacer euiSpacer--m emotion-euiSpacer-m"
+        class="euiSpacer euiSpacer--s emotion-euiSpacer-s"
       />
       <div
         class="euiText emotion-euiText-m-euiTextColor-subdued"
@@ -36,7 +36,7 @@ exports[`EuiEmptyPrompt is rendered 1`] = `
         </p>
       </div>
       <div
-        class="euiSpacer euiSpacer--l emotion-euiSpacer-l"
+        class="euiSpacer euiSpacer--m emotion-euiSpacer-m"
       />
       <div>
         Actions
@@ -51,7 +51,7 @@ exports[`EuiEmptyPrompt props actions renders alone 1`] = `
   class="euiPanel euiPanel--transparent euiEmptyPrompt emotion-euiPanel-m-transparent-euiEmptyPrompt-vertical"
 >
   <div
-    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-l"
+    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-m"
   >
     <div
       class="euiEmptyPrompt__content emotion-euiEmptyPrompt__content-vertical"
@@ -67,7 +67,7 @@ exports[`EuiEmptyPrompt props actions renders an array 1`] = `
   class="euiPanel euiPanel--transparent euiEmptyPrompt emotion-euiPanel-m-transparent-euiEmptyPrompt-vertical"
 >
   <div
-    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-l"
+    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-m"
   >
     <div
       class="euiEmptyPrompt__content emotion-euiEmptyPrompt__content-vertical"
@@ -96,7 +96,7 @@ exports[`EuiEmptyPrompt props body renders alone 1`] = `
   class="euiPanel euiPanel--transparent euiEmptyPrompt emotion-euiPanel-m-transparent-euiEmptyPrompt-vertical"
 >
   <div
-    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-l"
+    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-m"
   >
     <div
       class="euiEmptyPrompt__content emotion-euiEmptyPrompt__content-vertical"
@@ -116,7 +116,7 @@ exports[`EuiEmptyPrompt props color accent is rendered 1`] = `
   class="euiPanel euiPanel--accent euiEmptyPrompt emotion-euiPanel-m-accent-euiEmptyPrompt-vertical"
 >
   <div
-    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-l"
+    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-m"
   >
     <div
       class="euiEmptyPrompt__content emotion-euiEmptyPrompt__content-vertical"
@@ -130,7 +130,7 @@ exports[`EuiEmptyPrompt props color accentSecondary is rendered 1`] = `
   class="euiPanel euiPanel--accentSecondary euiEmptyPrompt emotion-euiPanel-m-accentSecondary-euiEmptyPrompt-vertical"
 >
   <div
-    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-l"
+    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-m"
   >
     <div
       class="euiEmptyPrompt__content emotion-euiEmptyPrompt__content-vertical"
@@ -144,7 +144,7 @@ exports[`EuiEmptyPrompt props color danger is rendered 1`] = `
   class="euiPanel euiPanel--danger euiEmptyPrompt emotion-euiPanel-m-danger-euiEmptyPrompt-vertical"
 >
   <div
-    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-l"
+    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-m"
   >
     <div
       class="euiEmptyPrompt__content emotion-euiEmptyPrompt__content-vertical"
@@ -158,7 +158,7 @@ exports[`EuiEmptyPrompt props color highlighted is rendered 1`] = `
   class="euiPanel euiPanel--highlighted euiEmptyPrompt emotion-euiPanel-m-highlighted-euiEmptyPrompt-vertical"
 >
   <div
-    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-l"
+    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-m"
   >
     <div
       class="euiEmptyPrompt__content emotion-euiEmptyPrompt__content-vertical"
@@ -172,7 +172,7 @@ exports[`EuiEmptyPrompt props color neutral is rendered 1`] = `
   class="euiPanel euiPanel--neutral euiEmptyPrompt emotion-euiPanel-m-neutral-euiEmptyPrompt-vertical"
 >
   <div
-    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-l"
+    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-m"
   >
     <div
       class="euiEmptyPrompt__content emotion-euiEmptyPrompt__content-vertical"
@@ -186,7 +186,7 @@ exports[`EuiEmptyPrompt props color plain is rendered 1`] = `
   class="euiPanel euiPanel--plain euiEmptyPrompt emotion-euiPanel-m-plain-hasShadow-euiEmptyPrompt-vertical"
 >
   <div
-    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-l"
+    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-m"
   >
     <div
       class="euiEmptyPrompt__content emotion-euiEmptyPrompt__content-vertical"
@@ -200,7 +200,7 @@ exports[`EuiEmptyPrompt props color primary is rendered 1`] = `
   class="euiPanel euiPanel--primary euiEmptyPrompt emotion-euiPanel-m-primary-euiEmptyPrompt-vertical"
 >
   <div
-    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-l"
+    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-m"
   >
     <div
       class="euiEmptyPrompt__content emotion-euiEmptyPrompt__content-vertical"
@@ -214,7 +214,7 @@ exports[`EuiEmptyPrompt props color risk is rendered 1`] = `
   class="euiPanel euiPanel--risk euiEmptyPrompt emotion-euiPanel-m-risk-euiEmptyPrompt-vertical"
 >
   <div
-    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-l"
+    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-m"
   >
     <div
       class="euiEmptyPrompt__content emotion-euiEmptyPrompt__content-vertical"
@@ -228,7 +228,7 @@ exports[`EuiEmptyPrompt props color subdued is rendered 1`] = `
   class="euiPanel euiPanel--subdued euiEmptyPrompt emotion-euiPanel-m-subdued-euiEmptyPrompt-vertical"
 >
   <div
-    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-l"
+    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-m"
   >
     <div
       class="euiEmptyPrompt__content emotion-euiEmptyPrompt__content-vertical"
@@ -242,7 +242,7 @@ exports[`EuiEmptyPrompt props color success is rendered 1`] = `
   class="euiPanel euiPanel--success euiEmptyPrompt emotion-euiPanel-m-success-euiEmptyPrompt-vertical"
 >
   <div
-    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-l"
+    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-m"
   >
     <div
       class="euiEmptyPrompt__content emotion-euiEmptyPrompt__content-vertical"
@@ -256,7 +256,7 @@ exports[`EuiEmptyPrompt props color transparent is rendered 1`] = `
   class="euiPanel euiPanel--transparent euiEmptyPrompt emotion-euiPanel-m-transparent-euiEmptyPrompt-vertical"
 >
   <div
-    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-l"
+    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-m"
   >
     <div
       class="euiEmptyPrompt__content emotion-euiEmptyPrompt__content-vertical"
@@ -270,7 +270,7 @@ exports[`EuiEmptyPrompt props color warning is rendered 1`] = `
   class="euiPanel euiPanel--warning euiEmptyPrompt emotion-euiPanel-m-warning-euiEmptyPrompt-vertical"
 >
   <div
-    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-l"
+    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-m"
   >
     <div
       class="euiEmptyPrompt__content emotion-euiEmptyPrompt__content-vertical"
@@ -284,14 +284,14 @@ exports[`EuiEmptyPrompt props footer renders alone 1`] = `
   class="euiPanel euiPanel--transparent euiEmptyPrompt emotion-euiPanel-m-transparent-euiEmptyPrompt-vertical"
 >
   <div
-    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-l"
+    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-m"
   >
     <div
       class="euiEmptyPrompt__content emotion-euiEmptyPrompt__content-vertical"
     />
   </div>
   <div
-    class="euiEmptyPrompt__footer emotion-euiEmptyPrompt__footer-l-transparent-roundedBorders"
+    class="euiEmptyPrompt__footer emotion-euiEmptyPrompt__footer-m-transparent-roundedBorders"
   >
     footer
   </div>
@@ -303,7 +303,7 @@ exports[`EuiEmptyPrompt props icon renders alone 1`] = `
   class="euiPanel euiPanel--transparent euiEmptyPrompt emotion-euiPanel-m-transparent-euiEmptyPrompt-vertical"
 >
   <div
-    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-l"
+    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-m"
   >
     <div
       class="euiEmptyPrompt__icon emotion-euiEmptyPrompt__icon-vertical"
@@ -324,7 +324,7 @@ exports[`EuiEmptyPrompt props iconType renders alone 1`] = `
   class="euiPanel euiPanel--transparent euiEmptyPrompt emotion-euiPanel-m-transparent-euiEmptyPrompt-vertical"
 >
   <div
-    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-l"
+    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-m"
   >
     <div
       class="euiEmptyPrompt__icon emotion-euiEmptyPrompt__icon-vertical"
@@ -346,7 +346,7 @@ exports[`EuiEmptyPrompt props iconType renders with iconColor 1`] = `
   class="euiPanel euiPanel--transparent euiEmptyPrompt emotion-euiPanel-m-transparent-euiEmptyPrompt-vertical"
 >
   <div
-    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-l"
+    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-m"
   >
     <div
       class="euiEmptyPrompt__icon emotion-euiEmptyPrompt__icon-vertical"
@@ -368,7 +368,7 @@ exports[`EuiEmptyPrompt props layout renders alone 1`] = `
   class="euiPanel euiPanel--transparent euiEmptyPrompt emotion-euiPanel-m-transparent-euiEmptyPrompt-horizontal"
 >
   <div
-    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-horizontal-l-l"
+    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-horizontal-m-m"
   >
     <div
       class="euiEmptyPrompt__content emotion-euiEmptyPrompt__content-horizontal"
@@ -439,7 +439,7 @@ exports[`EuiEmptyPrompt props styles are rendered 1`] = `
   style="background: yellow; min-width: 200px; max-width: 600px;"
 >
   <div
-    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-l"
+    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-m"
   >
     <div
       class="euiEmptyPrompt__content emotion-euiEmptyPrompt__content-vertical"
@@ -453,7 +453,7 @@ exports[`EuiEmptyPrompt props title renders alone 1`] = `
   class="euiPanel euiPanel--transparent euiEmptyPrompt emotion-euiPanel-m-transparent-euiEmptyPrompt-vertical"
 >
   <div
-    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-l"
+    class="euiEmptyPrompt__main emotion-euiEmptyPrompt__main-vertical-m"
   >
     <div
       class="euiEmptyPrompt__content emotion-euiEmptyPrompt__content-vertical"
diff --git a/packages/eui/src/components/empty_prompt/empty_prompt.styles.ts b/packages/eui/src/components/empty_prompt/empty_prompt.styles.ts
index 1fbde163f71..9c920f9d0a4 100644
--- a/packages/eui/src/components/empty_prompt/empty_prompt.styles.ts
+++ b/packages/eui/src/components/empty_prompt/empty_prompt.styles.ts
@@ -88,8 +88,7 @@ export const euiEmptyPromptStyles = (euiThemeContext: UseEuiTheme) => {
       `,
       horizontal: css`
         ${euiMinBreakpoint(euiThemeContext, 'l')} {
-          padding-block: ${euiTheme.size.l};
-          padding-inline: 0;
+          padding: ${euiTheme.size.l};
         }
       `,
     },
diff --git a/packages/eui/src/components/empty_prompt/empty_prompt.tsx b/packages/eui/src/components/empty_prompt/empty_prompt.tsx
index d16fe9539fc..4eb258704de 100644
--- a/packages/eui/src/components/empty_prompt/empty_prompt.tsx
+++ b/packages/eui/src/components/empty_prompt/empty_prompt.tsx
@@ -14,7 +14,7 @@ import React, {
 } from 'react';
 import classNames from 'classnames';
 
-import { useEuiMemoizedStyles } from '../../services';
+import { useEuiMemoizedStyles, useEuiTheme } from '../../services';
 import { CommonProps } from '../common';
 import { EuiTitle, EuiTitleSize } from '../title';
 import { EuiFlexGroup, EuiFlexItem } from '../flex';
@@ -86,7 +86,7 @@ export const EuiEmptyPrompt: FunctionComponent<EuiEmptyPromptProps> = ({
   iconColor: _iconColor,
   title,
   titleSize = 'm',
-  paddingSize = 'l',
+  paddingSize,
   body,
   actions,
   className,
@@ -98,12 +98,22 @@ export const EuiEmptyPrompt: FunctionComponent<EuiEmptyPromptProps> = ({
 }) => {
   const classes = classNames('euiEmptyPrompt', className);
   const styles = useEuiMemoizedStyles(euiEmptyPromptStyles);
+  const euiTheme = useEuiTheme();
+
+  // Get spacing values from theme, fallback to defaults for Amsterdam theme
+  const titleBodySpacing =
+    (euiTheme.euiTheme as any).spacing?.emptyPrompt?.titleBodySpacing ?? 'm';
+  const bodyActionsSpacing =
+    (euiTheme.euiTheme as any).spacing?.emptyPrompt?.bodyActionsSpacing ?? 'l';
+  const themePaddingSize =
+    (euiTheme.euiTheme as any).spacing?.emptyPrompt?.paddingSize ?? 'l';
   const cssStyles = [styles.euiEmptyPrompt, styles[layout]];
+  const finalPaddingSize = (paddingSize ?? themePaddingSize) as PaddingSize;
   const mainStyles = [
     styles.main.euiEmptyPrompt__main,
     styles.main[layout],
-    styles.main[paddingSize],
-    layout === 'horizontal' && styles.main.horizontalPadding[paddingSize],
+    styles.main[finalPaddingSize],
+    layout === 'horizontal' && styles.main.horizontalPadding[finalPaddingSize],
   ];
   const contentStyles = [
     styles.content.euiEmptyPrompt__content,
@@ -161,7 +171,7 @@ export const EuiEmptyPrompt: FunctionComponent<EuiEmptyPromptProps> = ({
     if (!footer) return null;
     const footerStyles = [
       styles.footer.euiEmptyPrompt__footer,
-      styles.footer[paddingSize],
+      styles.footer[finalPaddingSize],
       styles.footer[color],
       color === 'transparent' && !hasBorder && styles.footer.roundedBorders,
     ];
@@ -170,7 +180,7 @@ export const EuiEmptyPrompt: FunctionComponent<EuiEmptyPromptProps> = ({
         {footer}
       </div>
     );
-  }, [footer, paddingSize, color, hasBorder, styles.footer]);
+  }, [footer, finalPaddingSize, color, hasBorder, styles.footer]);
 
   return (
     <EuiPanel
@@ -186,9 +196,11 @@ export const EuiEmptyPrompt: FunctionComponent<EuiEmptyPromptProps> = ({
         {iconNode}
         <div className="euiEmptyPrompt__content" css={contentStyles}>
           {title && <EuiTitle size={titleSize}>{title}</EuiTitle>}
-          {title && body && <EuiSpacer size="m" />}
+          {title && body && <EuiSpacer size={titleBodySpacing} />}
           {body && <EuiText color="subdued">{body}</EuiText>}
-          {actionsNode && (body || title) && <EuiSpacer size="l" />}
+          {actionsNode && (body || title) && (
+            <EuiSpacer size={bodyActionsSpacing} />
+          )}
           {actionsNode}
         </div>
       </div>