diff --git a/CHANGELOG.md b/CHANGELOG.md
index 231e242a658..07f9a112f0d 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -17,6 +17,7 @@
 - Increased column width on `EuiTableHeaderCellCheckbox` to prevent `EuiCheckbox`'s focus ring from getting clipped in `EuiBasicTable` ([#2770](https://github.com/elastic/eui/pull/2770))
 - Fixed the display of `EuiButton` within `EuiControlBar` when `fill={true}` to be more consistent with other buttons ([#2781](https://github.com/elastic/eui/pull/2781))
 - Fixed `EuiFormControlLayout` from overwriting className for `prepend` nodes.  ([#2796](https://github.com/elastic/eui/pull/2796))
+- Fixed `useRenderToText` and `EuiButtonToggle` from attempting state updates on unmounted components ([#2797](https://github.com/elastic/eui/pull/2797))
 
 **Deprecations**
 
diff --git a/src/components/inner_text/render_to_text.tsx b/src/components/inner_text/render_to_text.tsx
index 33ec51d591d..07f1e14135d 100644
--- a/src/components/inner_text/render_to_text.tsx
+++ b/src/components/inner_text/render_to_text.tsx
@@ -1,21 +1,34 @@
-import React, { ReactNode, useEffect } from 'react';
+import React, { ReactNode, useCallback, useEffect, useRef } from 'react';
 import { render, unmountComponentAtNode } from 'react-dom';
 import { useInnerText } from './inner_text';
 
 export function useRenderToText(node: ReactNode, placeholder = ''): string {
   const [ref, text] = useInnerText(placeholder);
+  const hostNode = useRef<Element | null>(null);
+
+  const onUnmount = () => {
+    if (hostNode.current) {
+      unmountComponentAtNode(hostNode.current);
+      hostNode.current = null;
+    }
+  };
+
+  const setRef = useCallback(
+    (node: Element | null) => {
+      if (hostNode.current) {
+        ref(node);
+      }
+    },
+    [ref]
+  );
 
   useEffect(() => {
-    const hostNode = (document.createDocumentFragment() as unknown) as Element;
-    render(<div ref={ref}>{node}</div>, hostNode);
+    hostNode.current = (document.createDocumentFragment() as unknown) as Element;
+    render(<div ref={setRef}>{node}</div>, hostNode.current);
     return () => {
-      // since we're in React's lifecycle via `useEffect`, wait a
-      // tick to escape otherwise React performs multiple unmounts 🤷
-      requestAnimationFrame(() => {
-        unmountComponentAtNode(hostNode);
-      });
+      onUnmount();
     };
-  }, [node, ref]);
+  }, [node, setRef]);
 
   return text || placeholder;
 }