diff --git a/muted-tests.yml b/muted-tests.yml
index 75c7dc55f8a48..bbfb6a84179ec 100644
--- a/muted-tests.yml
+++ b/muted-tests.yml
@@ -258,24 +258,9 @@ tests:
 - class: org.elasticsearch.repositories.azure.AzureBlobContainerRetriesTests
   method: testWriteBlobWithRetries
   issue: https://github.com/elastic/elasticsearch/issues/144025
-- class: org.elasticsearch.test.apmintegration.MetricsApmIT
-  method: testJvmMetrics {withOTel=true}
-  issue: https://github.com/elastic/elasticsearch/issues/144166
-- class: org.elasticsearch.test.apmintegration.MetricsApmIT
-  method: testJvmMetrics {withOTel=false}
-  issue: https://github.com/elastic/elasticsearch/issues/144167
-- class: org.elasticsearch.test.apmintegration.MetricsApmIT
-  method: testApmIntegration {withOTel=false}
-  issue: https://github.com/elastic/elasticsearch/issues/144282
 - class: org.elasticsearch.reindex.management.ReindexGetRelocationIT
   method: testGetReindexFollowsRelocation
   issue: https://github.com/elastic/elasticsearch/issues/144364
-- class: org.elasticsearch.server.cli.APMJvmOptionsTests
-  method: testAPMAgentMetricsDisabledWhenOtelMetricsEnabled
-  issue: https://github.com/elastic/elasticsearch/issues/144357
-- class: org.elasticsearch.server.cli.APMJvmOptionsTests
-  method: testAPMAgentAlwaysAttached
-  issue: https://github.com/elastic/elasticsearch/issues/144358
 - class: org.elasticsearch.xpack.application.OpenAiServiceUpgradeIT
   method: testOpenAiEmbeddings {upgradedNodes=3}
   issue: https://github.com/elastic/elasticsearch/issues/144440
diff --git a/server/src/test/java/org/elasticsearch/monitor/metrics/SystemMetricsTests.java b/server/src/test/java/org/elasticsearch/monitor/metrics/SystemMetricsTests.java
index a87fb90b615ed..7126cb1815abf 100644
--- a/server/src/test/java/org/elasticsearch/monitor/metrics/SystemMetricsTests.java
+++ b/server/src/test/java/org/elasticsearch/monitor/metrics/SystemMetricsTests.java
@@ -10,6 +10,7 @@
 package org.elasticsearch.monitor.metrics;
 
 import org.elasticsearch.core.SuppressForbidden;
+import org.elasticsearch.monitor.process.ProcessProbe;
 import org.elasticsearch.telemetry.InstrumentType;
 import org.elasticsearch.telemetry.RecordingMeterRegistry;
 import org.elasticsearch.test.ESTestCase;
@@ -48,17 +49,19 @@ private static void testSystemMetrics(boolean emitOTelMetrics) {
             systemMetrics.start();
 
             List<String> registeredGauges = registry.getRecorder().getRegisteredMetrics(InstrumentType.LONG_GAUGE);
-            assertTrue("jvm.fd.used should always be registered", registeredGauges.contains("jvm.fd.used"));
-            assertTrue("jvm.fd.max should always be registered", registeredGauges.contains("jvm.fd.max"));
+            boolean openFdSupported = ProcessProbe.getOpenFileDescriptorCount() >= 0;
+            boolean maxFdSupported = ProcessProbe.getMaxFileDescriptorCount() >= 0;
+            assertEquals("jvm.fd.used should be registered if supported", openFdSupported, registeredGauges.contains("jvm.fd.used"));
+            assertEquals("jvm.fd.max should be registered if supported", maxFdSupported, registeredGauges.contains("jvm.fd.max"));
             assertEquals(
                 "jvm.file_descriptor.count should be registered if emitting OTel metrics",
-                registeredGauges.contains("jvm.file_descriptor.count"),
-                emitOTelMetrics
+                openFdSupported && emitOTelMetrics,
+                registeredGauges.contains("jvm.file_descriptor.count")
             );
             assertEquals(
                 "jvm.file_descriptor.limit should be registered if emitting OTel metrics",
-                registeredGauges.contains("jvm.file_descriptor.limit"),
-                emitOTelMetrics
+                maxFdSupported && emitOTelMetrics,
+                registeredGauges.contains("jvm.file_descriptor.limit")
             );
         }
     }
diff --git a/test/external-modules/apm-integration/src/javaRestTest/java/org/elasticsearch/test/apmintegration/AbstractMetricsIT.java b/test/external-modules/apm-integration/src/javaRestTest/java/org/elasticsearch/test/apmintegration/AbstractMetricsIT.java
index 7f44d655ff155..4d65a774d731f 100644
--- a/test/external-modules/apm-integration/src/javaRestTest/java/org/elasticsearch/test/apmintegration/AbstractMetricsIT.java
+++ b/test/external-modules/apm-integration/src/javaRestTest/java/org/elasticsearch/test/apmintegration/AbstractMetricsIT.java
@@ -9,6 +9,7 @@
 
 package org.elasticsearch.test.apmintegration;
 
+import org.apache.lucene.util.Constants;
 import org.elasticsearch.client.Request;
 import org.elasticsearch.logging.LogManager;
 import org.elasticsearch.logging.Logger;
@@ -179,6 +180,12 @@ public void testJvmMetrics() throws Exception {
             )
         );
 
+        if (Constants.WINDOWS) {
+            // JVM file descriptor metrics are not emitted on Windows.
+            valueAssertions.remove("jvm.fd.used");
+            valueAssertions.remove("jvm.fd.max");
+        }
+
         CountDownLatch finished = new CountDownLatch(1);
 
         Consumer<ReceivedTelemetry> messageConsumer = (ReceivedTelemetry msg) -> {