diff --git a/easybuild/easyconfigs/q/Qt5/Qt5-5.12.3-GCCcore-8.2.0.eb b/easybuild/easyconfigs/q/Qt5/Qt5-5.12.3-GCCcore-8.2.0.eb
new file mode 100644
index 000000000000..441e75e10e5b
--- /dev/null
+++ b/easybuild/easyconfigs/q/Qt5/Qt5-5.12.3-GCCcore-8.2.0.eb
@@ -0,0 +1,48 @@
+easyblock = 'EB_Qt'
+
+name = 'Qt5'
+version = '5.12.3'
+
+homepage = 'http://qt.io/'
+description = "Qt is a comprehensive cross-platform C++ application framework."
+
+toolchain = {'name': 'GCCcore', 'version': '8.2.0'}
+# disabling use of -ftree-vectorize is required to avoid compilation failures on some systems (e.g. Intel Skylake X)
+toolchainopts = {'vectorize': False}
+
+source_urls = [
+    'http://download.qt.io/official_releases/qt/%(version_major_minor)s/%(version)s/single/',
+    'http://download.qt.io/archive/qt/%(version_major_minor)s/%(version)s/single/'
+]
+sources = ['qt-everywhere-src-%(version)s.tar.xz']
+patches = ['Qt5-%(version)s_fix-avx2.patch']
+checksums = [
+    '6462ac74c00ff466487d8ef8d0922971aa5b1d5b33c0753308ec9d57711f5a42',  # qt-everywhere-src-5.12.3.tar.xz
+    '6f46005f056bf9e6ff3e5d012a874d18ee03b33e685941f2979c970be91a9dbc',  # Qt5-5.12.3_fix-avx2.patch
+]
+
+builddependencies = [
+    ('binutils', '2.31.1'),
+    ('pkg-config', '0.29.2'),
+    ('Bison', '3.0.5'),
+    ('flex', '2.6.4'),
+    ('Python', '2.7.15'),
+]
+
+dependencies = [
+    ('GLib', '2.60.1'),
+    ('libpng', '1.6.36'),
+    ('X11', '20190311'),
+    ('libGLU', '9.0.0'),
+    ('NSS', '3.42.1'),
+    ('DBus', '1.13.8'),
+    ('gperf', '3.1'),
+]
+
+# qtgamepad needs recent kernel/libevdev (fails on RHEL 6.x)
+configopts = '-skip qtgamepad'
+
+# make sure QtWebEngine component is being built & installed
+check_qtwebengine = True
+
+moduleclass = 'devel'
diff --git a/easybuild/easyconfigs/q/Qt5/Qt5-5.12.3_fix-avx2.patch b/easybuild/easyconfigs/q/Qt5/Qt5-5.12.3_fix-avx2.patch
new file mode 100644
index 000000000000..a2c9a0cdf289
--- /dev/null
+++ b/easybuild/easyconfigs/q/Qt5/Qt5-5.12.3_fix-avx2.patch
@@ -0,0 +1,14 @@
+build qdrawhelper_avx2.cpp with -mavx2 rather than -march=core-avx2 to avoid compilation failures on non-AVX2 systems
+cfr. https://bugreports.qt.io/browse/QTBUG-71564 (and https://gcc.gnu.org/bugzilla/show_bug.cgi?id=69471)
+author: Kenneth Hoste (HPC-UGent)
+--- qt-everywhere-src-5.12.3.orig/qtbase/mkspecs/common/gcc-base.conf	2019-04-09 11:51:26.000000000 +0200
++++ qt-everywhere-src-5.12.3/qtbase/mkspecs/common/gcc-base.conf	2019-05-01 19:21:50.683489624 +0200
+@@ -109,7 +109,7 @@
+ QMAKE_CFLAGS_MIPS_DSPR2 += -mdspr2
+ 
+ # -march=haswell is supported as of GCC 4.9 and Clang 3.6
+-QMAKE_CFLAGS_ARCH_HASWELL           = -march=core-avx2
++QMAKE_CFLAGS_ARCH_HASWELL           = -mavx2
+ 
+ # Wrapper tools that understand .o/.a files with GIMPLE instead of machine code
+ QMAKE_AR_LTCG           = gcc-ar cqs