diff --git a/easybuild/easyconfigs/m/Mathematica/Mathematica-14.1.0.eb b/easybuild/easyconfigs/m/Mathematica/Mathematica-14.1.0.eb
new file mode 100644
index 00000000000..16714c67742
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+++ b/easybuild/easyconfigs/m/Mathematica/Mathematica-14.1.0.eb
@@ -0,0 +1,25 @@
+name = "Mathematica"
+version = "14.1.0"
+
+homepage = "https://www.wolfram.com/mathematica"
+docurls = "https://reference.wolfram.com/language/"
+description = """
+    Mathematica is a computational software program
+    used in many scientific, engineering, mathematical and computing fields.
+"""
+download_instructions = "Download from https://user.wolfram.com/portal/myProducts.html"
+postinstallmsgs = [
+    "This Mathematica/Wolfram installer includes Qt6. Please ensure that your compute nodes ",
+    "have the necessary dependencies available (see https://support.wolfram.com/59044), or alternatively, ",
+    "load the Qt6 module together with this module. ",
+]
+modloadmsg = "To start the notebook interface, commonly called the front end, use the wolframnb CLI command."
+
+toolchain = SYSTEM
+
+sources = ["Wolfram_%(version)s_LIN.sh"]
+checksums = ["3c2a63c2a03a342fa2c2f63175d601966179faf97beabf8ca086002fdd56167b"]
+
+license_server = "license.example.com"
+
+moduleclass = "math"