diff --git a/easybuild/easyconfigs/f/Flye/Flye-2.8.3-GCC-10.2.0.eb b/easybuild/easyconfigs/f/Flye/Flye-2.8.3-GCC-10.2.0.eb
index 6ab5c7765273..3511a76c9ea7 100644
--- a/easybuild/easyconfigs/f/Flye/Flye-2.8.3-GCC-10.2.0.eb
+++ b/easybuild/easyconfigs/f/Flye/Flye-2.8.3-GCC-10.2.0.eb
@@ -11,7 +11,11 @@ toolchain = {'name': 'GCC', 'version': '10.2.0'}
 
 source_urls = ['https://github.com/fenderglass/Flye/archive/']
 sources = ['%(version)s.tar.gz']
-checksums = ['070f9fbee28eef8e8f87aaecc048053f50a8102a3715e71b16c9c46819a4e07c']
+patches = ['Flye-2.8.3_fix-aarch64.patch']
+checksums = [
+    '070f9fbee28eef8e8f87aaecc048053f50a8102a3715e71b16c9c46819a4e07c',  # 2.8.3.tar.gz
+    '938cc6fc8206c3cb5ed1ad8e7071494c4887f7a298980a931fe094e1a9eb3a0b',  # Flye-2.8.3_fix-aarch64.patch
+]
 
 dependencies = [('Python', '3.8.6')]
 
diff --git a/easybuild/easyconfigs/f/Flye/Flye-2.8.3_fix-aarch64.patch b/easybuild/easyconfigs/f/Flye/Flye-2.8.3_fix-aarch64.patch
new file mode 100644
index 000000000000..f8ef59e01d1d
--- /dev/null
+++ b/easybuild/easyconfigs/f/Flye/Flye-2.8.3_fix-aarch64.patch
@@ -0,0 +1,11 @@
+diff -ru Flye.orig/src/Makefile Flye/src/Makefile
+--- Flye.orig/src/Makefile	2021-06-14 16:02:46.709190000 +0200
++++ Flye/src/Makefile	2021-06-14 16:03:31.146916000 +0200
+@@ -1,6 +1,6 @@
+ .PHONY: all clean debug profile
+ 
+-CXXFLAGS += -Wall -Wextra -pthread -std=c++11 -g
++CXXFLAGS += -Wall -Wextra -pthread -std=c++11 -g -fsigned-char
+ LDFLAGS += -pthread -std=c++11 -rdynamic
+ 
+ MODULES_BIN := ${BIN_DIR}/flye-modules