diff --git a/easybuild/easyconfigs/f/Flye/Flye-2.8.3-GCC-10.2.0.eb b/easybuild/easyconfigs/f/Flye/Flye-2.8.3-GCC-10.2.0.eb
index fbfc9e597899..6ab5c7765273 100644
--- a/easybuild/easyconfigs/f/Flye/Flye-2.8.3-GCC-10.2.0.eb
+++ b/easybuild/easyconfigs/f/Flye/Flye-2.8.3-GCC-10.2.0.eb
@@ -18,6 +18,9 @@ dependencies = [('Python', '3.8.6')]
 download_dep_fail = True
 use_pip = True
 
+if ARCH == "aarch64":
+    preinstallopts = 'export arm_neon=1 && export aarch64=1 && '
+
 sanity_check_paths = {
     'files': ['bin/flye'],
     'dirs': ['lib/python%(pyshortver)s/site-packages'],