diff --git a/duckdb b/duckdb
index b8a06e4..24c295a 160000
--- a/duckdb
+++ b/duckdb
@@ -1 +1 @@
-Subproject commit b8a06e4a22672e254cd0baa68a3dbed2eb51c56e
+Subproject commit 24c295a9dd3f793222fc965f2f41ade148854526
diff --git a/src/httpfs.cpp b/src/httpfs.cpp
index 802581e..a11af95 100644
--- a/src/httpfs.cpp
+++ b/src/httpfs.cpp
@@ -729,7 +729,7 @@ void HTTPFileHandle::LoadFileInfo() {
 			return;
 		} else {
 			// HEAD request fail, use Range request for another try (read only one byte)
-			if (flags.OpenForReading() && res->status != HTTPStatusCode::NotFound_404) {
+			if (flags.OpenForReading() && res->status != HTTPStatusCode::NotFound_404 && res->status != HTTPStatusCode::MovedPermanently_301) {
 				auto range_res = hfs.GetRangeRequest(*this, path, {}, 0, nullptr, 2);
 				if (range_res->status != HTTPStatusCode::PartialContent_206 &&
 				    range_res->status != HTTPStatusCode::Accepted_202 && range_res->status != HTTPStatusCode::OK_200) {
diff --git a/src/httpfs_extension.cpp b/src/httpfs_extension.cpp
index 79d9923..9070621 100644
--- a/src/httpfs_extension.cpp
+++ b/src/httpfs_extension.cpp
@@ -70,7 +70,7 @@ static void LoadInternal(ExtensionLoader &loader) {
 	config.AddExtensionOption("ca_cert_file", "Path to a custom certificate file for self-signed certificates.",
 	                          LogicalType::VARCHAR, Value(""));
 	// Global S3 config
-	config.AddExtensionOption("s3_region", "S3 Region", LogicalType::VARCHAR, Value("us-east-1"));
+	config.AddExtensionOption("s3_region", "S3 Region", LogicalType::VARCHAR);
 	config.AddExtensionOption("s3_access_key_id", "S3 Access Key ID", LogicalType::VARCHAR);
 	config.AddExtensionOption("s3_secret_access_key", "S3 Access Key", LogicalType::VARCHAR);
 	config.AddExtensionOption("s3_session_token", "S3 Session Token", LogicalType::VARCHAR);
diff --git a/src/include/s3fs.hpp b/src/include/s3fs.hpp
index 525e0dd..a7e933e 100644
--- a/src/include/s3fs.hpp
+++ b/src/include/s3fs.hpp
@@ -231,7 +231,7 @@ class S3FileSystem : public HTTPFileSystem {
 		return true;
 	}
 
-	static string GetS3BadRequestError(S3AuthParams &s3_auth_params);
+	static string GetS3BadRequestError(S3AuthParams &s3_auth_params, string correct_region = "");
 	static string GetS3AuthError(S3AuthParams &s3_auth_params);
 	static string GetGCSAuthError(S3AuthParams &s3_auth_params);
 	static HTTPException GetS3Error(S3AuthParams &s3_auth_params, const HTTPResponse &response, const string &url);
diff --git a/src/s3fs.cpp b/src/s3fs.cpp
index cbdecba..72eddc3 100644
--- a/src/s3fs.cpp
+++ b/src/s3fs.cpp
@@ -872,6 +872,7 @@ void S3FileHandle::Initialize(optional_ptr<FileOpener> opener) {
 		ErrorData error(ex);
 		bool refreshed_secret = false;
 		if (error.Type() == ExceptionType::IO || error.Type() == ExceptionType::HTTP) {
+			// legacy endpoint (no region) returns 400
 			auto context = opener->TryGetClientContext();
 			if (context) {
 				auto transaction = CatalogTransaction::GetSystemCatalogTransaction(*context);
@@ -887,9 +888,13 @@ void S3FileHandle::Initialize(optional_ptr<FileOpener> opener) {
 			auto &extra_info = error.ExtraInfo();
 			auto entry = extra_info.find("status_code");
 			if (entry != extra_info.end()) {
-				if (entry->second == "400") {
-					// 400: BAD REQUEST
-					auto extra_text = S3FileSystem::GetS3BadRequestError(auth_params);
+				if (entry->second == "301" || entry->second == "400") {
+					auto new_region = extra_info.find("header_x-amz-bucket-region");
+					string correct_region = "";
+					if (new_region != extra_info.end()) {
+						correct_region = new_region->second;
+					}
+					auto extra_text = S3FileSystem::GetS3BadRequestError(auth_params, correct_region);
 					throw Exception(error.Type(), error.RawMessage() + extra_text, extra_info);
 				}
 				if (entry->second == "403") {
@@ -1138,12 +1143,15 @@ bool S3FileSystem::ListFiles(const string &directory, const std::function<void(c
 	return true;
 }
 
-string S3FileSystem::GetS3BadRequestError(S3AuthParams &s3_auth_params) {
+string S3FileSystem::GetS3BadRequestError(S3AuthParams &s3_auth_params, string correct_region) {
 	string extra_text = "\n\nBad Request - this can be caused by the S3 region being set incorrectly.";
 	if (s3_auth_params.region.empty()) {
 		extra_text += "\n* No region is provided.";
 	} else {
-		extra_text += "\n* Provided region is \"" + s3_auth_params.region + "\"";
+		extra_text += "\n* Provided region is: \"" + s3_auth_params.region + "\"";
+	}
+	if (!correct_region.empty()) {
+		extra_text += "\n* Correct region is: \"" + correct_region + "\"";
 	}
 	return extra_text;
 }
diff --git a/test/sql/copy/csv/test_csv_remote.test b/test/sql/copy/csv/test_csv_remote.test
index 4144082..9e51585 100644
--- a/test/sql/copy/csv/test_csv_remote.test
+++ b/test/sql/copy/csv/test_csv_remote.test
@@ -7,15 +7,26 @@ require httpfs
 statement ok
 PRAGMA enable_verification
 
+# Test load from url with query string
+query IIIIIIIIIIII
+FROM sniff_csv('https://github.com/duckdb/duckdb/raw/main/data/csv/customer.csv?v=1')
+----
+,	"	(empty)	\n	(empty)	0	0	[{'name': column00, 'type': BIGINT}, {'name': column01, 'type': VARCHAR}, {'name': column02, 'type': BIGINT}, {'name': column03, 'type': BIGINT}, {'name': column04, 'type': BIGINT}, {'name': column05, 'type': BIGINT}, {'name': column06, 'type': BIGINT}, {'name': column07, 'type': VARCHAR}, {'name': column08, 'type': VARCHAR}, {'name': column09, 'type': VARCHAR}, {'name': column10, 'type': VARCHAR}, {'name': column11, 'type': BIGINT}, {'name': column12, 'type': BIGINT}, {'name': column13, 'type': BIGINT}, {'name': column14, 'type': VARCHAR}, {'name': column15, 'type': VARCHAR}, {'name': column16, 'type': VARCHAR}, {'name': column17, 'type': BIGINT}]	NULL	NULL	NULL	FROM read_csv('https://github.com/duckdb/duckdb/raw/main/data/csv/customer.csv?v=1', auto_detect=false, delim=',', quote='"', escape='', new_line='\n', skip=0, comment='', header=false, columns={'column00': 'BIGINT', 'column01': 'VARCHAR', 'column02': 'BIGINT', 'column03': 'BIGINT', 'column04': 'BIGINT', 'column05': 'BIGINT', 'column06': 'BIGINT', 'column07': 'VARCHAR', 'column08': 'VARCHAR', 'column09': 'VARCHAR', 'column10': 'VARCHAR', 'column11': 'BIGINT', 'column12': 'BIGINT', 'column13': 'BIGINT', 'column14': 'VARCHAR', 'column15': 'VARCHAR', 'column16': 'VARCHAR', 'column17': 'BIGINT'});
+
+
+# This test abuses the LOCAL_EXTENSION_REPO env to make sure tests are only run when running extension tests
+# in duckdb/duckdb. Otherwise you need to pass a data dir when exex
+
+require-env LOCAL_EXTENSION_REPO
 
 # regular csv file
 query ITTTIITITTIIII nosort webpagecsv
-SELECT * FROM read_csv_auto('duckdb/data/csv/real/web_page.csv') ORDER BY 1;
+SELECT * FROM read_csv_auto('data/csv/real/web_page.csv') ORDER BY 1;
 ----
 
 # file with gzip
 query IIIIIIIIIIIIIII nosort lineitemcsv
-SELECT * FROM read_csv_auto('duckdb/data/csv/lineitem1k.tbl.gz') ORDER BY ALL;
+SELECT * FROM read_csv_auto('data/csv/lineitem1k.tbl.gz') ORDER BY ALL;
 ----
 
 query ITTTIITITTIIII nosort webpagecsv
@@ -25,10 +36,3 @@ SELECT * FROM read_csv_auto('https://raw.githubusercontent.com/duckdb/duckdb/mai
 query IIIIIIIIIIIIIII nosort lineitemcsv
 select * from read_csv_auto('https://raw.githubusercontent.com/duckdb/duckdb/main/data/csv/lineitem1k.tbl.gz') ORDER BY ALL;
 ----
-
-
-# Test load from url with query string
-query IIIIIIIIIIII
-FROM sniff_csv('https://github.com/duckdb/duckdb/raw/main/data/csv/customer.csv?v=1')
-----
-,	"	(empty)	\n	(empty)	0	0	[{'name': column00, 'type': BIGINT}, {'name': column01, 'type': VARCHAR}, {'name': column02, 'type': BIGINT}, {'name': column03, 'type': BIGINT}, {'name': column04, 'type': BIGINT}, {'name': column05, 'type': BIGINT}, {'name': column06, 'type': BIGINT}, {'name': column07, 'type': VARCHAR}, {'name': column08, 'type': VARCHAR}, {'name': column09, 'type': VARCHAR}, {'name': column10, 'type': VARCHAR}, {'name': column11, 'type': BIGINT}, {'name': column12, 'type': BIGINT}, {'name': column13, 'type': BIGINT}, {'name': column14, 'type': VARCHAR}, {'name': column15, 'type': VARCHAR}, {'name': column16, 'type': VARCHAR}, {'name': column17, 'type': BIGINT}]	NULL	NULL	NULL	FROM read_csv('https://github.com/duckdb/duckdb/raw/main/data/csv/customer.csv?v=1', auto_detect=false, delim=',', quote='"', escape='', new_line='\n', skip=0, comment='', header=false, columns={'column00': 'BIGINT', 'column01': 'VARCHAR', 'column02': 'BIGINT', 'column03': 'BIGINT', 'column04': 'BIGINT', 'column05': 'BIGINT', 'column06': 'BIGINT', 'column07': 'VARCHAR', 'column08': 'VARCHAR', 'column09': 'VARCHAR', 'column10': 'VARCHAR', 'column11': 'BIGINT', 'column12': 'BIGINT', 'column13': 'BIGINT', 'column14': 'VARCHAR', 'column15': 'VARCHAR', 'column16': 'VARCHAR', 'column17': 'BIGINT'});
diff --git a/test/sql/copy/s3/url_encode.test b/test/sql/copy/s3/url_encode.test
index 66cbd5c..f5a5912 100644
--- a/test/sql/copy/s3/url_encode.test
+++ b/test/sql/copy/s3/url_encode.test
@@ -132,12 +132,20 @@ set s3_endpoint='';
 statement error
 SELECT * FROM 's3://test-bucket/whatever.parquet';
 ----
-<REGEX>:.*Unknown error for HTTP HEAD to 'http://test-bucket.s3.eu-west-1.amazonaws.com/whatever.parquet'.*
+<REGEX>:.*HTTP Error: Unable to connect to URL .*http://test-bucket.s3.eu-west-1.amazonaws.com/whatever.parquet.*: 301 .Moved Permanently..*
+.*
+.*Bad Request - this can be caused by the S3 region being set incorrectly.*
+.*Provided region is: .eu-west-1.*
+.*Correct region is: .us-east-1.*
 
 statement error
 SELECT * FROM 'r2://test-bucket/whatever.parquet';
 ----
-<REGEX>:.*Unknown error for HTTP HEAD to 'http://test-bucket.s3.eu-west-1.amazonaws.com/whatever.parquet'.*
+<REGEX>:.*HTTP Error: Unable to connect to URL .*http://test-bucket.s3.eu-west-1.amazonaws.com/whatever.parquet.*: 301 .Moved Permanently..*
+.*
+.*Bad Request - this can be caused by the S3 region being set incorrectly.*
+.*Provided region is: .eu-west-1.*
+.*Correct region is: .us-east-1.*
 
 statement error
 SELECT * FROM 'gcs://test-bucket/whatever.parquet';