Sublineage of CH.1.1.3 with S:S486P(T23018C) and ORF1b:V1520L (G18025T) (36 seqs in 4 conturies)

[HynnSpylor]

Defining mutations: CH.1.1.3>C4900A(ORF1a:H1545Q)>T23018C (S:F486P), G18025T(ORF1b:V1520L), A21979G, C24358T
GISAID query: Spike_F486P, Spike_K444T, Spike_S255P
Earliest seq: 2023-02-24 (New Zealand, EPI_ISL_17252157)
Most recent seq: 2023-03-22 (Australia, EPI_ISL_17408871)
Countries detected: New Zealand (4), Australia (2), Singapore (1)
Usher Tree:

https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_323e_466550.json

Description:
Another attempt for CH* to get S:F486P. It has been observed in 3 countries, but still too small and needs to watch for a time.
Genomes:
EPI_ISL_17252157, EPI_ISL_17252184, EPI_ISL_17347132, EPI_ISL_17388946, EPI_ISL_17408871, EPI_ISL_17422917, EPI_ISL_17422938

[HynnSpylor]

11 seqs in 3 countries now (New Zealand 5, Australia 5, Singapore 1)

[FedeGueli]

@corneliusroemer this differently from others CH.1.1+486P seems going . If new seqs will come next week i would designate it.

[HynnSpylor]

23 seqs now

[FedeGueli]

Now this one has reached 36 and it is the first time we see 486P being able to spread significatively in a CH.1.1 backbone.
To be noticed a cluster that further changed S:T444 to M and another one from NZL with Orf7a:H47N

https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice77_genome_3238d_d9c900.json?label=id:node_7314370

And there was a very recent importation to England .

In my view even if it is not super fast it could deserve a designation.
cc @InfrPopGen @corneliusroemer

[HynnSpylor]

@FedeGueli Also notice that 5/7 of the ORF7a:H47N branch in New Zealand get S:G213E (site 213 is G in BA.2.75* lineages while E in almost XBB*)