diff --git a/cloudpickle/cloudpickle.py b/cloudpickle/cloudpickle.py
index ad8166121..f3e2b93e0 100644
--- a/cloudpickle/cloudpickle.py
+++ b/cloudpickle/cloudpickle.py
@@ -339,7 +339,13 @@ def save_function(self, obj, name=None):
         Determines what kind of function obj is (e.g. lambda, defined at
         interactive prompt, etc) and handles the pickling appropriately.
         """
-        if obj in _BUILTIN_TYPE_CONSTRUCTORS:
+        try:
+            should_special_case = obj in _BUILTIN_TYPE_CONSTRUCTORS
+        except TypeError:
+            # Methods of builtin types aren't hashable in python 2.
+            should_special_case = False
+
+        if should_special_case:
             # We keep a special-cased cache of built-in type constructors at
             # global scope, because these functions are structured very
             # differently in different python versions and implementations (for
diff --git a/tests/cloudpickle_test.py b/tests/cloudpickle_test.py
index 44bb93709..e7b139266 100644
--- a/tests/cloudpickle_test.py
+++ b/tests/cloudpickle_test.py
@@ -877,6 +877,12 @@ def test_pickle_reraise(self):
             with pytest.raises((exc_type, pickle.PicklingError)):
                 cloudpickle.dumps(obj)
 
+    def test_unhashable_function(self):
+        d = {'a': 1}
+        depickled_method = pickle_depickle(d.get)
+        self.assertEquals(depickled_method('a'), 1)
+        self.assertEquals(depickled_method('b'), None)
+
 
 class Protocol2CloudPickleTest(CloudPickleTest):