diff --git a/.github/workflows/CI.yml b/.github/workflows/CI.yml
index 9d4e266024..a89e25f686 100644
--- a/.github/workflows/CI.yml
+++ b/.github/workflows/CI.yml
@@ -95,6 +95,7 @@ jobs:
           {test_type: 'integration_testing', label: 'array'},
           {test_type: 'integration_testing', label: 'bijectors'},
           {test_type: 'integration_testing', label: 'diff_tests'},
+          {test_type: 'integration_testing', label: 'diffeq'},
           {test_type: 'integration_testing', label: 'dispatch_doctor'},
           {test_type: 'integration_testing', label: 'distributions'},
           {test_type: 'integration_testing', label: 'dynamicppl'},
diff --git a/test/integration_testing/diffeq/Project.toml b/test/integration_testing/diffeq/Project.toml
new file mode 100644
index 0000000000..98e015ff48
--- /dev/null
+++ b/test/integration_testing/diffeq/Project.toml
@@ -0,0 +1,6 @@
+[deps]
+Mooncake = "da2b9cff-9c12-43a0-ae48-6db2b0edb7d6"
+OrdinaryDiffEq = "1dea7af3-3e70-54e6-95c3-0bf5283fa5ed"
+SciMLSensitivity = "1ed8b502-d754-442c-8d5d-10ac956f44a1"
+StableRNGs = "860ef19b-820b-49d6-a774-d7a799459cd3"
+Test = "8dfed614-e22c-5e08-85e1-65c5234f0b40"
\ No newline at end of file
diff --git a/test/integration_testing/diffeq/diffeq.jl b/test/integration_testing/diffeq/diffeq.jl
new file mode 100644
index 0000000000..00ae9e1081
--- /dev/null
+++ b/test/integration_testing/diffeq/diffeq.jl
@@ -0,0 +1,53 @@
+using Pkg
+Pkg.activate(@__DIR__)
+Pkg.develop(; path=joinpath(@__DIR__, "..", "..", ".."))
+
+using OrdinaryDiffEq, SciMLSensitivity, Mooncake, StableRNGs, Test
+using Mooncake.TestUtils: test_rule
+
+# Helper function for Mooncake gradient computation  
+mooncake_gradient(f, x) = Mooncake.value_and_gradient!!(Mooncake.build_rrule(f, x), f, x)[2][2]
+
+# Define the ODE function from the original issue
+odef(du, u, p, t) = du .= u .* p
+
+# Define the sensitivity loss function from the original issue
+struct senseloss0{T}
+    sense::T
+end
+
+function (f::senseloss0)(u0p)
+    prob = ODEProblem{true}(odef, u0p[1:1], (0.0, 1.0), u0p[2:2])
+    sum(solve(prob, Tsit5(), abstol = 1e-12, reltol = 1e-12, saveat = 0.1))
+end
+
+@testset "diffeq" begin
+    rng = StableRNG(123456)
+    
+    # Test parameters from the original issue
+    u0p = [2.0, 3.0]
+    
+    @testset "senseloss0 with InterpolatingAdjoint" begin
+        sense_func = senseloss0(InterpolatingAdjoint())
+        
+        # First test that the function works
+        @testset "Function evaluation" begin
+            result = sense_func(u0p)
+            @test result isa Real
+            @test isfinite(result)
+        end
+        
+        # Test Mooncake gradient computation 
+        @testset "mooncake_gradient computation" begin
+            dup_mc = mooncake_gradient(sense_func, u0p)
+            @test dup_mc isa Vector
+            @test length(dup_mc) == 2
+            @test all(isfinite, dup_mc)
+        end
+        
+        # Test with Mooncake's test_rule
+        @testset "test_rule evaluation" begin
+            test_rule(rng, sense_func, u0p; is_primitive=false, unsafe_perturb=true)
+        end
+    end
+end
\ No newline at end of file