diff --git a/crates/uv-cli/src/lib.rs b/crates/uv-cli/src/lib.rs
index 6befc34b95950..f135870a054de 100644
--- a/crates/uv-cli/src/lib.rs
+++ b/crates/uv-cli/src/lib.rs
@@ -2533,6 +2533,10 @@ pub struct PipFreezeArgs {
     #[arg(long)]
     pub exclude_editable: bool,
 
+    /// Exclude the specified package(s) from the output.
+    #[arg(long)]
+    pub r#exclude: Vec<PackageName>,
+
     /// Validate the Python environment, to detect packages with missing dependencies and other
     /// issues.
     #[arg(long, overrides_with("no_strict"))]
diff --git a/crates/uv/src/commands/pip/freeze.rs b/crates/uv/src/commands/pip/freeze.rs
index fd8f3cb177349..0d5f3d7054f5d 100644
--- a/crates/uv/src/commands/pip/freeze.rs
+++ b/crates/uv/src/commands/pip/freeze.rs
@@ -1,3 +1,4 @@
+use std::collections::HashSet;
 use std::fmt::Write;
 use std::path::PathBuf;
 
@@ -10,6 +11,7 @@ use uv_cache::Cache;
 use uv_distribution_types::{Diagnostic, InstalledDistKind, Name};
 use uv_fs::Simplified;
 use uv_installer::SitePackages;
+use uv_normalize::PackageName;
 use uv_preview::Preview;
 use uv_python::PythonPreference;
 use uv_python::{EnvironmentPreference, Prefix, PythonEnvironment, PythonRequest, Target};
@@ -21,6 +23,7 @@ use crate::printer::Printer;
 /// Enumerate the installed packages in the current environment.
 pub(crate) fn pip_freeze(
     exclude_editable: bool,
+    exclude: &HashSet<PackageName>,
     strict: bool,
     python: Option<&str>,
     system: bool,
@@ -80,7 +83,15 @@ pub(crate) fn pip_freeze(
     site_packages
         .iter()
         .flat_map(uv_installer::SitePackages::iter)
-        .filter(|dist| !(exclude_editable && dist.is_editable()))
+        .filter(|dist| {
+            if exclude_editable && dist.is_editable() {
+                return false;
+            }
+            if exclude.contains(dist.name()) {
+                return false;
+            }
+            true
+        })
         .sorted_unstable_by(|a, b| a.name().cmp(b.name()).then(a.version().cmp(b.version())))
         .map(|dist| match &dist.kind {
             InstalledDistKind::Registry(dist) => {
diff --git a/crates/uv/src/lib.rs b/crates/uv/src/lib.rs
index 3560faa27412d..4a37963efddbf 100644
--- a/crates/uv/src/lib.rs
+++ b/crates/uv/src/lib.rs
@@ -976,6 +976,7 @@ async fn run(mut cli: Cli) -> Result<ExitStatus> {
 
             commands::pip_freeze(
                 args.exclude_editable,
+                &args.exclude,
                 args.settings.strict,
                 args.settings.python.as_deref(),
                 args.settings.system,
diff --git a/crates/uv/src/settings.rs b/crates/uv/src/settings.rs
index 4a3da83f478af..ab7d288dcc67b 100644
--- a/crates/uv/src/settings.rs
+++ b/crates/uv/src/settings.rs
@@ -1,3 +1,4 @@
+use std::collections::HashSet;
 use std::env::VarError;
 use std::num::NonZeroUsize;
 use std::path::PathBuf;
@@ -3024,6 +3025,7 @@ impl PipUninstallSettings {
 #[derive(Debug, Clone)]
 pub(crate) struct PipFreezeSettings {
     pub(crate) exclude_editable: bool,
+    pub(crate) exclude: HashSet<PackageName>,
     pub(crate) paths: Option<Vec<PathBuf>>,
     pub(crate) settings: PipSettings,
 }
@@ -3037,6 +3039,7 @@ impl PipFreezeSettings {
     ) -> Self {
         let PipFreezeArgs {
             exclude_editable,
+            exclude,
             strict,
             no_strict,
             python,
@@ -3050,6 +3053,7 @@ impl PipFreezeSettings {
 
         Self {
             exclude_editable,
+            exclude: exclude.into_iter().collect(),
             paths,
             settings: PipSettings::combine(
                 PipOptions {
diff --git a/crates/uv/tests/it/pip_freeze.rs b/crates/uv/tests/it/pip_freeze.rs
index ce1ef8b1f6cd2..d4f4b9fc0ce76 100644
--- a/crates/uv/tests/it/pip_freeze.rs
+++ b/crates/uv/tests/it/pip_freeze.rs
@@ -574,3 +574,41 @@ fn freeze_prefix() -> Result<()> {
 
     Ok(())
 }
+
+#[test]
+fn freeze_exclude() {
+    let context = TestContext::new("3.12");
+
+    let prefix = context.temp_dir.child("prefix");
+
+    // Install packages to a prefix directory.
+    context
+        .pip_install()
+        .arg("MarkupSafe")
+        .arg("tomli")
+        .arg("--prefix")
+        .arg(prefix.path())
+        .assert()
+        .success();
+
+    // Run `pip freeze --exclude MarkupSafe`.
+    uv_snapshot!(context.filters(), context.pip_freeze().arg("--exclude").arg("MarkupSafe").arg("--prefix").arg(prefix.path()), @r###"
+    success: true
+    exit_code: 0
+    ----- stdout -----
+    tomli==2.0.1
+
+    ----- stderr -----
+    "###
+    );
+
+    // Run `pip freeze --exclude MarkupSafe --exclude tomli`.
+    uv_snapshot!(context.filters(), context.pip_freeze().arg("--exclude").arg("MarkupSafe").arg("--exclude").arg("tomli").arg("--prefix").arg(prefix.path()), @r###"
+    success: true
+    exit_code: 0
+    ----- stdout -----
+
+    ----- stderr -----
+    "###
+    );
+}