diff --git a/crates/uv-client/src/base_client.rs b/crates/uv-client/src/base_client.rs
index 1421e95d10665..43a59139fa8c3 100644
--- a/crates/uv-client/src/base_client.rs
+++ b/crates/uv-client/src/base_client.rs
@@ -1,5 +1,5 @@
 use itertools::Itertools;
-use reqwest::{Client, ClientBuilder, Response};
+use reqwest::{Client, ClientBuilder, Proxy, Response};
 use reqwest_middleware::{ClientWithMiddleware, Middleware};
 use reqwest_retry::policies::ExponentialBackoff;
 use reqwest_retry::{
@@ -56,6 +56,7 @@ pub struct BaseClientBuilder<'a> {
     url_auth_policies: Option<UrlAuthPolicies>,
     default_timeout: Duration,
     extra_middleware: Option<ExtraMiddleware>,
+    proxies: Vec<Proxy>,
 }
 
 /// A list of user-defined middlewares to be applied to the client.
@@ -90,6 +91,7 @@ impl BaseClientBuilder<'_> {
             url_auth_policies: None,
             default_timeout: Duration::from_secs(30),
             extra_middleware: None,
+            proxies: vec![],
         }
     }
 }
@@ -161,6 +163,12 @@ impl<'a> BaseClientBuilder<'a> {
         self
     }
 
+    #[must_use]
+    pub fn proxy(mut self, proxy: Proxy) -> Self {
+        self.proxies.push(proxy);
+        self
+    }
+
     pub fn is_offline(&self) -> bool {
         matches!(self.connectivity, Connectivity::Offline)
     }
@@ -301,6 +309,13 @@ impl<'a> BaseClientBuilder<'a> {
             client_builder
         };
 
+        // apply proxies
+        let mut client_builder = client_builder;
+        for p in &self.proxies {
+            client_builder = client_builder.proxy(p.clone());
+        }
+        let client_builder = client_builder;
+
         client_builder
             .build()
             .expect("Failed to build HTTP client.")
diff --git a/crates/uv-client/src/registry_client.rs b/crates/uv-client/src/registry_client.rs
index 6f4c927f12523..ea476e1d7d95b 100644
--- a/crates/uv-client/src/registry_client.rs
+++ b/crates/uv-client/src/registry_client.rs
@@ -8,7 +8,7 @@ use async_http_range_reader::AsyncHttpRangeReader;
 use futures::{FutureExt, StreamExt, TryStreamExt};
 use http::HeaderMap;
 use itertools::Either;
-use reqwest::{Response, StatusCode};
+use reqwest::{Proxy, Response, StatusCode};
 use reqwest_middleware::ClientWithMiddleware;
 use tokio::sync::Semaphore;
 use tracing::{info_span, instrument, trace, warn, Instrument};
@@ -133,6 +133,12 @@ impl<'a> RegistryClientBuilder<'a> {
         self
     }
 
+    #[must_use]
+    pub fn proxy(mut self, proxy: Proxy) -> Self {
+        self.base_client_builder = self.base_client_builder.proxy(proxy);
+        self
+    }
+
     pub fn build(self) -> RegistryClient {
         // Build a base client
         let builder = self.base_client_builder;