diff --git a/crates/uv-installer/src/site_packages.rs b/crates/uv-installer/src/site_packages.rs
index 065b81bf92d1e..267113d01596d 100644
--- a/crates/uv-installer/src/site_packages.rs
+++ b/crates/uv-installer/src/site_packages.rs
@@ -287,17 +287,17 @@ impl SitePackages {
         constraints: &[NameRequirementSpecification],
         markers: &ResolverMarkerEnvironment,
     ) -> Result<SatisfiesResult> {
-        // Collect the constraints.
-        let constraints: FxHashMap<&PackageName, Vec<&Requirement>> =
-            constraints
-                .iter()
-                .fold(FxHashMap::default(), |mut constraints, constraint| {
-                    constraints
-                        .entry(&constraint.requirement.name)
-                        .or_default()
-                        .push(&constraint.requirement);
-                    constraints
-                });
+        // Collect the constraints, filtering them by their marker environment.
+        let constraints: FxHashMap<&PackageName, Vec<&Requirement>> = constraints
+            .iter()
+            .filter(|constraint| constraint.requirement.evaluate_markers(Some(markers), &[]))
+            .fold(FxHashMap::default(), |mut constraints, constraint| {
+                constraints
+                    .entry(&constraint.requirement.name)
+                    .or_default()
+                    .push(&constraint.requirement);
+                constraints
+            });
 
         let mut stack = Vec::with_capacity(requirements.len());
         let mut seen = FxHashSet::with_capacity_and_hasher(requirements.len(), FxBuildHasher);
diff --git a/crates/uv/tests/it/pip_install.rs b/crates/uv/tests/it/pip_install.rs
index 5bc1a0d946d18..7b8a702ea6f4e 100644
--- a/crates/uv/tests/it/pip_install.rs
+++ b/crates/uv/tests/it/pip_install.rs
@@ -3288,6 +3288,56 @@ fn install_constraints_respects_offline_mode() {
     );
 }
 
+/// Test that constraint markers are respected when validating the current environment (i.e., we
+/// skip resolution entirely).
+#[test]
+fn install_constraints_with_markers() -> Result<()> {
+    let context = TestContext::new("3.12");
+    let requirements_txt = context.temp_dir.child("requirements.txt");
+    requirements_txt.write_str("pytest")?;
+
+    // Create a constraints file with a marker that is not relevant to the current environment.
+    let constraints_txt = context.temp_dir.child("constraints.txt");
+    constraints_txt.write_str("pytest==8.0.0; sys_platform == 'nonexistent-platform'")?;
+
+    uv_snapshot!(context.pip_install()
+        .arg("-r")
+        .arg("requirements.txt")
+        .arg("--constraint")
+        .arg("constraints.txt"), @r###"
+    success: true
+    exit_code: 0
+    ----- stdout -----
+
+    ----- stderr -----
+    Resolved 4 packages in [TIME]
+    Prepared 4 packages in [TIME]
+    Installed 4 packages in [TIME]
+     + iniconfig==2.0.0
+     + packaging==24.0
+     + pluggy==1.4.0
+     + pytest==8.1.1
+    "###
+    );
+
+    // We should only see "Audited" here; no need to resolve.
+    uv_snapshot!(context.pip_install()
+        .arg("-r")
+        .arg("requirements.txt")
+        .arg("--constraint")
+        .arg("constraints.txt"), @r###"
+    success: true
+    exit_code: 0
+    ----- stdout -----
+
+    ----- stderr -----
+    Audited 1 package in [TIME]
+    "###
+    );
+
+    Ok(())
+}
+
 /// Tests that we can install `polars==0.14.0`, which has this odd dependency
 /// requirement in its wheel metadata: `pyarrow>=4.0.*; extra == 'pyarrow'`.
 ///