diff --git a/crates/uv-python/src/interpreter.rs b/crates/uv-python/src/interpreter.rs
index 5795031d5cb..b2c48a1900f 100644
--- a/crates/uv-python/src/interpreter.rs
+++ b/crates/uv-python/src/interpreter.rs
@@ -27,6 +27,7 @@ use uv_pep508::{MarkerEnvironment, StringVersion};
 use uv_platform::{Arch, Libc, Os};
 use uv_platform_tags::{Platform, Tags, TagsError, TagsOptions};
 use uv_pypi_types::{ResolverMarkerEnvironment, Scheme};
+use uv_static::EnvVars;
 
 use crate::implementation::LenientImplementationName;
 use crate::managed::ManagedPythonInstallations;
@@ -1149,6 +1150,8 @@ impl InterpreterInfo {
         };
 
         let canonical = canonicalize_executable(&absolute).map_err(handle_io_error)?;
+        let python_executable = env::var_os(EnvVars::PYTHONEXECUTABLE).map(PathBuf::from);
+        let pyvenv_launcher = env::var_os(EnvVars::PYVENV_LAUNCHER).map(PathBuf::from);
 
         let cache_entry = cache.entry(
             CacheBucket::Interpreter,
@@ -1170,7 +1173,13 @@ impl InterpreterInfo {
             // absolute path refers to different interpreters with matching ctimes, e.g., if you
             // have a `.venv/bin/python` pointing to both Python 3.12 and Python 3.13 that were
             // modified at the same time.
-            format!("{}.msgpack", cache_digest(&(&absolute, &canonical))),
+            //
+            // Launcher overrides can also change the reported executable and virtual environment
+            // without changing either executable path.
+            format!(
+                "{}.msgpack",
+                cache_digest(&(&absolute, &canonical, &python_executable, &pyvenv_launcher))
+            ),
         );
 
         // We check the timestamp of the canonicalized executable to check if an underlying
diff --git a/crates/uv-static/src/env_vars.rs b/crates/uv-static/src/env_vars.rs
index 6bddc4ca443..6be14772915 100644
--- a/crates/uv-static/src/env_vars.rs
+++ b/crates/uv-static/src/env_vars.rs
@@ -1077,6 +1077,11 @@ impl EnvVars {
     #[attr_added_in("0.7.13")]
     pub const PYTHONHOME: &'static str = "PYTHONHOME";
 
+    /// Overrides the executable Python uses to determine its environment.
+    #[attr_hidden]
+    #[attr_added_in("next release")]
+    pub const PYTHONEXECUTABLE: &'static str = "PYTHONEXECUTABLE";
+
     /// Used to correctly detect virtual environments when using trampolines.
     #[attr_hidden]
     #[attr_added_in("0.7.13")]
diff --git a/crates/uv/tests/python/python_find.rs b/crates/uv/tests/python/python_find.rs
index adbc33f45af..d4436da2184 100644
--- a/crates/uv/tests/python/python_find.rs
+++ b/crates/uv/tests/python/python_find.rs
@@ -146,7 +146,7 @@ fn python_find_cached_launcher_override() {
     // `PYTHONEXECUTABLE` makes the requested `other` interpreter report `.venv`.
     uv_snapshot!(context.filters(), context.python_find()
         .arg(&requested_python)
-        .env("PYTHONEXECUTABLE", &override_python), @"
+        .env(EnvVars::PYTHONEXECUTABLE, &override_python), @"
     exit_code: 0 (success)
     ----- stdout -----
     [VENV]/bin/python3
@@ -155,10 +155,10 @@ fn python_find_cached_launcher_override() {
     // Without `PYTHONEXECUTABLE`, this should return `other`, not the cached `.venv`.
     uv_snapshot!(context.filters(), context.python_find()
         .arg(&requested_python)
-        .env_remove("PYTHONEXECUTABLE"), @"
+        .env_remove(EnvVars::PYTHONEXECUTABLE), @"
     exit_code: 0 (success)
     ----- stdout -----
-    [VENV]/bin/python3
+    [TEMP_DIR]/other/bin/python3
     ");
 }
 
diff --git a/hawk.toml b/hawk.toml
index f8627f16a10..434c1cbe198 100644
--- a/hawk.toml
+++ b/hawk.toml
@@ -207,15 +207,6 @@ kind = "inherent_associated_constant"
 level = "expect"
 reason = "read by generated activation scripts"
 
-[[override]]
-lint = "hawk::dead_public"
-crate = "uv_static"
-item = "env_vars::EnvVars::PYVENV_LAUNCHER"
-kind = "inherent_associated_constant"
-level = "expect"
-target = "cfg(not(windows))"
-reason = "used by Windows trampoline launchers"
-
 [[override]]
 lint = "hawk::dead_public"
 crate = "uv_static"