diff --git a/crates/ty_python_semantic/resources/mdtest/metaclass.md b/crates/ty_python_semantic/resources/mdtest/metaclass.md
index 3c4762fe8fefe..2a05f779f1061 100644
--- a/crates/ty_python_semantic/resources/mdtest/metaclass.md
+++ b/crates/ty_python_semantic/resources/mdtest/metaclass.md
@@ -247,6 +247,58 @@ class A[T: str](metaclass=M): ...
 reveal_type(A.__class__)  # revealed: <class 'M'>
 ```
 
+## Generic metaclass
+
+### Fully specialized
+
+A generic metaclass fully specialized with concrete types is fine:
+
+```toml
+[environment]
+python-version = "3.13"
+```
+
+```py
+class Foo[T](type):
+    x: T
+
+class Bar(metaclass=Foo[int]): ...
+
+reveal_type(Bar.__class__)  # revealed: <class 'Foo[int]'>
+```
+
+### Parameterized by type variables (legacy)
+
+A generic metaclass parameterized by type variables is not supported:
+
+```py
+from typing import TypeVar, Generic
+
+T = TypeVar("T")
+
+class GenericMeta(type, Generic[T]): ...
+
+# error: [invalid-metaclass] "Generic metaclasses are not supported"
+class GenericMetaInstance(metaclass=GenericMeta[T]): ...
+```
+
+### Parameterized by type variables (PEP 695)
+
+The same applies using PEP 695 syntax:
+
+```toml
+[environment]
+python-version = "3.13"
+```
+
+```py
+class Foo[T](type):
+    x: T
+
+# error: [invalid-metaclass]
+class Bar[T](metaclass=Foo[T]): ...
+```
+
 ## Metaclasses of metaclasses
 
 ```py
diff --git a/crates/ty_python_semantic/src/types/class.rs b/crates/ty_python_semantic/src/types/class.rs
index 2316040ea8878..6532df131e769 100644
--- a/crates/ty_python_semantic/src/types/class.rs
+++ b/crates/ty_python_semantic/src/types/class.rs
@@ -2883,6 +2883,23 @@ impl<'db> StaticClassLiteral<'db> {
         let module = parsed_module(db, self.file(db)).load(db);
 
         let explicit_metaclass = self.explicit_metaclass(db, &module);
+
+        // Generic metaclasses parameterized by type variables are not supported.
+        // `metaclass=Meta[int]` is fine, but `metaclass=Meta[T]` is not.
+        // See: https://typing.python.org/en/latest/spec/generics.html#generic-metaclasses
+        if let Some(Type::GenericAlias(alias)) = explicit_metaclass {
+            let specialization_has_typevars = alias
+                .specialization(db)
+                .types(db)
+                .iter()
+                .any(|ty| ty.has_typevar_or_typevar_instance(db));
+            if specialization_has_typevars {
+                return Err(MetaclassError {
+                    kind: MetaclassErrorKind::GenericMetaclass,
+                });
+            }
+        }
+
         let (metaclass, class_metaclass_was_from) = if let Some(metaclass) = explicit_metaclass {
             (metaclass, self)
         } else if let Some(base_class) = base_classes.next() {
@@ -8276,6 +8293,8 @@ pub(super) enum MetaclassErrorKind<'db> {
         /// inferred metaclass of a base class. This helps us give better error messages in diagnostics.
         candidate1_is_base_class: bool,
     },
+    /// The metaclass is a parameterized generic class, which is not supported.
+    GenericMetaclass,
     /// The metaclass is not callable
     NotCallable(Type<'db>),
     /// The metaclass is of a union type whose some members are not callable
diff --git a/crates/ty_python_semantic/src/types/infer/builder.rs b/crates/ty_python_semantic/src/types/infer/builder.rs
index 9d1c6670c624d..1d89d403771a3 100644
--- a/crates/ty_python_semantic/src/types/infer/builder.rs
+++ b/crates/ty_python_semantic/src/types/infer/builder.rs
@@ -1222,6 +1222,13 @@ impl<'db, 'ast> TypeInferenceBuilder<'db, 'ast> {
                             ));
                         }
                     }
+                    MetaclassErrorKind::GenericMetaclass => {
+                        if let Some(builder) =
+                            self.context.report_lint(&INVALID_METACLASS, class_node)
+                        {
+                            builder.into_diagnostic("Generic metaclasses are not supported");
+                        }
+                    }
                     MetaclassErrorKind::NotCallable(ty) => {
                         if let Some(builder) =
                             self.context.report_lint(&INVALID_METACLASS, class_node)