diff --git a/crates/ruff_linter/resources/test/fixtures/pyupgrade/UP017.py b/crates/ruff_linter/resources/test/fixtures/pyupgrade/UP017.py
index b4a4aa96ccf30..1a49d2a844204 100644
--- a/crates/ruff_linter/resources/test/fixtures/pyupgrade/UP017.py
+++ b/crates/ruff_linter/resources/test/fixtures/pyupgrade/UP017.py
@@ -26,3 +26,14 @@ def func():
     import datetime as dt
 
     print(dt.timezone.utc)
+
+
+def func():
+    import datetime
+
+    print((
+        datetime
+        .timezone  # text
+        .utc
+    ))
+
diff --git a/crates/ruff_linter/src/rules/pyupgrade/rules/datetime_utc_alias.rs b/crates/ruff_linter/src/rules/pyupgrade/rules/datetime_utc_alias.rs
index c37281831f64a..b229be1e4866d 100644
--- a/crates/ruff_linter/src/rules/pyupgrade/rules/datetime_utc_alias.rs
+++ b/crates/ruff_linter/src/rules/pyupgrade/rules/datetime_utc_alias.rs
@@ -1,3 +1,4 @@
+use ruff_diagnostics::Applicability;
 use ruff_python_ast::Expr;
 
 use ruff_macros::{ViolationMetadata, derive_message_formats};
@@ -28,6 +29,9 @@ use crate::{Edit, Fix, FixAvailability, Violation};
 /// datetime.UTC
 /// ```
 ///
+/// ## Fix safety
+/// This rule's fix is marked as safe, unless the expression contains comments.
+///
 /// ## Options
 /// - `target-version`
 ///
@@ -67,7 +71,18 @@ pub(crate) fn datetime_utc_alias(checker: &Checker, expr: &Expr) {
                 checker.semantic(),
             )?;
             let reference_edit = Edit::range_replacement(binding, expr.range());
-            Ok(Fix::safe_edits(import_edit, [reference_edit]))
+
+            let applicability = if checker.comment_ranges().intersects(expr.range()) {
+                Applicability::Unsafe
+            } else {
+                Applicability::Safe
+            };
+
+            Ok(Fix::applicable_edits(
+                import_edit,
+                [reference_edit],
+                applicability,
+            ))
         });
     }
 }
diff --git a/crates/ruff_linter/src/rules/pyupgrade/snapshots/ruff_linter__rules__pyupgrade__tests__datetime_utc_alias_py311.snap b/crates/ruff_linter/src/rules/pyupgrade/snapshots/ruff_linter__rules__pyupgrade__tests__datetime_utc_alias_py311.snap
index 1f92bdb01b70e..f2318a22c878a 100644
--- a/crates/ruff_linter/src/rules/pyupgrade/snapshots/ruff_linter__rules__pyupgrade__tests__datetime_utc_alias_py311.snap
+++ b/crates/ruff_linter/src/rules/pyupgrade/snapshots/ruff_linter__rules__pyupgrade__tests__datetime_utc_alias_py311.snap
@@ -79,3 +79,28 @@ help: Convert to `datetime.UTC` alias
 27 | 
    -     print(dt.timezone.utc)
 28 +     print(dt.UTC)
+29 | 
+30 | 
+31 | def func():
+
+UP017 [*] Use `datetime.UTC` alias
+  --> UP017.py:35:9
+   |
+34 |       print((
+35 | /         datetime
+36 | |         .timezone  # text
+37 | |         .utc
+   | |____________^
+38 |       ))
+   |
+help: Convert to `datetime.UTC` alias
+32 |     import datetime
+33 | 
+34 |     print((
+   -         datetime
+   -         .timezone  # text
+   -         .utc
+35 +         datetime.UTC
+36 |     ))
+37 | 
+note: This is an unsafe fix and may change runtime behavior