diff --git a/crates/ruff_linter/resources/test/fixtures/flake8_executable/EXE003_uv.py b/crates/ruff_linter/resources/test/fixtures/flake8_executable/EXE003_uv.py
index 30c64dc45b750..7b112690ae3fd 100755
--- a/crates/ruff_linter/resources/test/fixtures/flake8_executable/EXE003_uv.py
+++ b/crates/ruff_linter/resources/test/fixtures/flake8_executable/EXE003_uv.py
@@ -1,3 +1,23 @@
 #!/usr/bin/env -S uv run
 print("hello world")
 
+#!/usr/bin/env uv --offline run
+print("offline")
+
+#!/usr/bin/env uv --color=auto run
+print("color")
+
+#!/usr/bin/env uv --quiet run --script
+print("quiet run script")
+
+#!/usr/bin/env uv tool run
+print("uv tool")
+
+#!/usr/bin/env uvx
+print("uvx")
+
+#!/usr/bin/env uvx --quiet
+print("uvx quiet")
+
+#!/usr/bin/env uv_not_really_run
+print("this should fail")
diff --git a/crates/ruff_linter/src/rules/flake8_executable/mod.rs b/crates/ruff_linter/src/rules/flake8_executable/mod.rs
index 765810d4103b7..76e79aefa58e7 100644
--- a/crates/ruff_linter/src/rules/flake8_executable/mod.rs
+++ b/crates/ruff_linter/src/rules/flake8_executable/mod.rs
@@ -14,24 +14,24 @@ mod tests {
     use crate::test::test_path;
     use crate::{assert_diagnostics, settings};
 
-    #[test_case(Path::new("EXE001_1.py"))]
-    #[test_case(Path::new("EXE001_2.py"))]
-    #[test_case(Path::new("EXE001_3.py"))]
-    #[test_case(Path::new("EXE002_1.py"))]
-    #[test_case(Path::new("EXE002_2.py"))]
-    #[test_case(Path::new("EXE002_3.py"))]
-    #[test_case(Path::new("EXE003.py"))]
-    #[test_case(Path::new("EXE003_uv.py"))]
-    #[test_case(Path::new("EXE003_uv_tool.py"))]
-    #[test_case(Path::new("EXE003_uvx.py"))]
-    #[test_case(Path::new("EXE004_1.py"))]
-    #[test_case(Path::new("EXE004_2.py"))]
-    #[test_case(Path::new("EXE004_3.py"))]
-    #[test_case(Path::new("EXE004_4.py"))]
-    #[test_case(Path::new("EXE005_1.py"))]
-    #[test_case(Path::new("EXE005_2.py"))]
-    #[test_case(Path::new("EXE005_3.py"))]
-    fn rules(path: &Path) -> Result<()> {
+    #[test_case(Rule::ShebangNotExecutable, Path::new("EXE001_1.py"))]
+    #[test_case(Rule::ShebangNotExecutable, Path::new("EXE001_2.py"))]
+    #[test_case(Rule::ShebangNotExecutable, Path::new("EXE001_3.py"))]
+    #[test_case(Rule::ShebangMissingExecutableFile, Path::new("EXE002_1.py"))]
+    #[test_case(Rule::ShebangMissingExecutableFile, Path::new("EXE002_2.py"))]
+    #[test_case(Rule::ShebangMissingExecutableFile, Path::new("EXE002_3.py"))]
+    #[test_case(Rule::ShebangMissingPython, Path::new("EXE003.py"))]
+    #[test_case(Rule::ShebangMissingPython, Path::new("EXE003_uv.py"))]
+    #[test_case(Rule::ShebangMissingPython, Path::new("EXE003_uv_tool.py"))]
+    #[test_case(Rule::ShebangMissingPython, Path::new("EXE003_uvx.py"))]
+    #[test_case(Rule::ShebangLeadingWhitespace, Path::new("EXE004_1.py"))]
+    #[test_case(Rule::ShebangLeadingWhitespace, Path::new("EXE004_2.py"))]
+    #[test_case(Rule::ShebangLeadingWhitespace, Path::new("EXE004_3.py"))]
+    #[test_case(Rule::ShebangLeadingWhitespace, Path::new("EXE004_4.py"))]
+    #[test_case(Rule::ShebangNotFirstLine, Path::new("EXE005_1.py"))]
+    #[test_case(Rule::ShebangNotFirstLine, Path::new("EXE005_2.py"))]
+    #[test_case(Rule::ShebangNotFirstLine, Path::new("EXE005_3.py"))]
+    fn rules(rule: Rule, path: &Path) -> Result<()> {
         if is_wsl::is_wsl() {
             // these rules are always ignored on WSL, so skip testing them in a WSL environment
             // see https://github.com/astral-sh/ruff/pull/21724 for latest discussion
@@ -41,13 +41,7 @@ mod tests {
         let snapshot = path.to_string_lossy().into_owned();
         let diagnostics = test_path(
             Path::new("flake8_executable").join(path).as_path(),
-            &settings::LinterSettings::for_rules(vec![
-                Rule::ShebangNotExecutable,
-                Rule::ShebangMissingExecutableFile,
-                Rule::ShebangLeadingWhitespace,
-                Rule::ShebangNotFirstLine,
-                Rule::ShebangMissingPython,
-            ]),
+            &settings::LinterSettings::for_rule(rule),
         )?;
         assert_diagnostics!(snapshot, diagnostics);
         Ok(())
diff --git a/crates/ruff_linter/src/rules/flake8_executable/rules/shebang_missing_python.rs b/crates/ruff_linter/src/rules/flake8_executable/rules/shebang_missing_python.rs
index 968e5340cae9d..b3666c21c6413 100644
--- a/crates/ruff_linter/src/rules/flake8_executable/rules/shebang_missing_python.rs
+++ b/crates/ruff_linter/src/rules/flake8_executable/rules/shebang_missing_python.rs
@@ -1,11 +1,30 @@
-use ruff_text_size::TextRange;
+use std::sync::LazyLock;
 
+use regex::Regex;
 use ruff_macros::{ViolationMetadata, derive_message_formats};
+use ruff_text_size::TextRange;
 
 use crate::Violation;
 use crate::checkers::ast::LintContext;
 use crate::comments::shebang::ShebangDirective;
 
+static UV_RUN_REGEX: LazyLock<Regex> = LazyLock::new(|| {
+    Regex::new(
+        r"(?x)
+        \b
+        (?:
+            # Part A: uv or uv tool (these MUST be followed by run)
+            (?:uv|uv\s+tool) \s+ (?:--?[a-zA-Z][\w-]*(?:[=\s]\S+)?\s+)* run
+            |
+            # Part B: uvx (stands alone, run is optional/redundant)
+            uvx (?: \s+ .* )?
+        )
+        \b
+    ",
+    )
+    .unwrap()
+});
+
 /// ## What it does
 /// Checks for a shebang directive in `.py` files that does not contain `python`,
 /// `pytest`, or `uv run`.
@@ -48,12 +67,7 @@ pub(crate) fn shebang_missing_python(
     shebang: &ShebangDirective,
     context: &LintContext,
 ) {
-    if shebang.contains("python")
-        || shebang.contains("pytest")
-        || shebang.contains("uv run")
-        || shebang.contains("uvx")
-        || shebang.contains("uv tool run")
-    {
+    if shebang.contains("python") || shebang.contains("pytest") || UV_RUN_REGEX.is_match(shebang) {
         return;
     }
 
diff --git a/crates/ruff_linter/src/rules/flake8_executable/snapshots/ruff_linter__rules__flake8_executable__tests__EXE003_uv.py.snap b/crates/ruff_linter/src/rules/flake8_executable/snapshots/ruff_linter__rules__flake8_executable__tests__EXE003_uv.py.snap
index 26e075ae3eb6e..6ac799eb3f8b7 100644
--- a/crates/ruff_linter/src/rules/flake8_executable/snapshots/ruff_linter__rules__flake8_executable__tests__EXE003_uv.py.snap
+++ b/crates/ruff_linter/src/rules/flake8_executable/snapshots/ruff_linter__rules__flake8_executable__tests__EXE003_uv.py.snap
@@ -1,4 +1,12 @@
 ---
 source: crates/ruff_linter/src/rules/flake8_executable/mod.rs
 ---
-
+EXE003 Shebang should contain `python`, `pytest`, or `uv run`
+  --> EXE003_uv.py:22:1
+   |
+20 | print("uvx quiet")
+21 |
+22 | #!/usr/bin/env uv_not_really_run
+   | ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
+23 | print("this should fail")
+   |
diff --git a/crates/ruff_linter/src/rules/flake8_executable/snapshots/ruff_linter__rules__flake8_executable__tests__EXE004_3.py.snap b/crates/ruff_linter/src/rules/flake8_executable/snapshots/ruff_linter__rules__flake8_executable__tests__EXE004_3.py.snap
index 14bb184162e14..26e075ae3eb6e 100644
--- a/crates/ruff_linter/src/rules/flake8_executable/snapshots/ruff_linter__rules__flake8_executable__tests__EXE004_3.py.snap
+++ b/crates/ruff_linter/src/rules/flake8_executable/snapshots/ruff_linter__rules__flake8_executable__tests__EXE004_3.py.snap
@@ -1,9 +1,4 @@
 ---
 source: crates/ruff_linter/src/rules/flake8_executable/mod.rs
 ---
-EXE005 Shebang should be at the beginning of the file
- --> EXE004_3.py:2:7
-  |
-2 | pass  #!/usr/bin/env python
-  |       ^^^^^^^^^^^^^^^^^^^^^
-  |
+