diff --git a/crates/ruff_python_formatter/resources/test/fixtures/ruff/statement/import_from.py b/crates/ruff_python_formatter/resources/test/fixtures/ruff/statement/import_from.py
index 879fe9aeffb03..31555cb2b6e20 100644
--- a/crates/ruff_python_formatter/resources/test/fixtures/ruff/statement/import_from.py
+++ b/crates/ruff_python_formatter/resources/test/fixtures/ruff/statement/import_from.py
@@ -37,3 +37,7 @@
 )
 
 from tqdm .  auto import tqdm
+
+# Regression test for https://github.com/astral-sh/ruff/issues/19138
+from y import(e as#
+r)
diff --git a/crates/ruff_python_formatter/src/comments/placement.rs b/crates/ruff_python_formatter/src/comments/placement.rs
index 0ec2aa6d2fbe3..33fdab92313b3 100644
--- a/crates/ruff_python_formatter/src/comments/placement.rs
+++ b/crates/ruff_python_formatter/src/comments/placement.rs
@@ -312,6 +312,7 @@ fn handle_enclosed_comment<'a>(
             handle_leading_class_with_decorators_comment(comment, class_def)
         }
         AnyNodeRef::StmtImportFrom(import_from) => handle_import_from_comment(comment, import_from),
+        AnyNodeRef::Alias(alias) => handle_alias_from_comment(comment, alias, source),
         AnyNodeRef::StmtWith(with_) => handle_with_comment(comment, with_),
         AnyNodeRef::ExprCall(_) => handle_call_comment(comment),
         AnyNodeRef::ExprStringLiteral(_) => match comment.enclosing_parent() {
@@ -1967,6 +1968,29 @@ fn handle_import_from_comment<'a>(
     }
 }
 
+fn handle_alias_from_comment<'a>(
+    comment: DecoratedComment<'a>,
+    alias: &'a ast::Alias,
+    source: &str,
+) -> CommentPlacement<'a> {
+    if let Some(asname) = alias.asname.as_ref() {
+        // Determine if the comment is between the `as` token and the alias name.
+        let mut tokens =
+            SimpleTokenizer::new(source, TextRange::new(alias.name.end(), asname.start()))
+                .skip_trivia();
+
+        if let Some(as_token) = tokens.find(|t| t.kind() == SimpleTokenKind::As)
+            && (comment.line_position().is_end_of_line() || comment.line_position().is_own_line())
+            && as_token.end() <= comment.start()
+            && comment.end() <= asname.start()
+        {
+            return CommentPlacement::trailing(alias, comment);
+        }
+    }
+
+    CommentPlacement::Default(comment)
+}
+
 /// Attach an enclosed end-of-line comment to a [`ast::StmtWith`].
 ///
 /// For example, given:
diff --git a/crates/ruff_python_formatter/tests/snapshots/format@statement__import_from.py.snap b/crates/ruff_python_formatter/tests/snapshots/format@statement__import_from.py.snap
index 45626f76cd8cf..ee5b2a47bf923 100644
--- a/crates/ruff_python_formatter/tests/snapshots/format@statement__import_from.py.snap
+++ b/crates/ruff_python_formatter/tests/snapshots/format@statement__import_from.py.snap
@@ -44,6 +44,10 @@ from a import \
 )
 
 from tqdm .  auto import tqdm
+
+# Regression test for https://github.com/astral-sh/ruff/issues/19138
+from y import(e as#
+r)
 ```
 
 ## Output
@@ -120,4 +124,9 @@ from a import (  # comment
 )
 
 from tqdm.auto import tqdm
+
+# Regression test for https://github.com/astral-sh/ruff/issues/19138
+from y import (
+    e as r,  #
+)
 ```