diff --git a/sql/core/src/main/scala/org/apache/spark/sql/execution/command/ddl.scala b/sql/core/src/main/scala/org/apache/spark/sql/execution/command/ddl.scala
index c0ccdca98e05..76f65e21190d 100644
--- a/sql/core/src/main/scala/org/apache/spark/sql/execution/command/ddl.scala
+++ b/sql/core/src/main/scala/org/apache/spark/sql/execution/command/ddl.scala
@@ -679,7 +679,8 @@ case class AlterTableSetLocationCommand(
           } else {
             table.withNewStorage(locationUri = Some(location))
           }
-        catalog.alterTable(newTable)
+        val newTableWithInvalidatedStats = newTable.copy(stats = None)
+        catalog.alterTable(newTableWithInvalidatedStats)
     }
     Seq.empty[Row]
   }
diff --git a/sql/hive/src/test/scala/org/apache/spark/sql/hive/StatisticsSuite.scala b/sql/hive/src/test/scala/org/apache/spark/sql/hive/StatisticsSuite.scala
index 9956706929cd..6a9945c87d20 100644
--- a/sql/hive/src/test/scala/org/apache/spark/sql/hive/StatisticsSuite.scala
+++ b/sql/hive/src/test/scala/org/apache/spark/sql/hive/StatisticsSuite.scala
@@ -290,6 +290,27 @@ class StatisticsSuite extends QueryTest with TestHiveSingleton with SQLTestUtils
     }
   }
 
+  test("alter table set location after analyze table") {
+    val textTable = "textTable"
+    withTable(textTable) {
+      sql(s"CREATE TABLE $textTable (key STRING, value STRING) STORED AS TEXTFILE")
+      sql(s"INSERT INTO TABLE $textTable SELECT * FROM src")
+      sql(s"ANALYZE TABLE $textTable COMPUTE STATISTICS")
+      checkStats(
+        textTable, isDataSourceTable = false, hasSizeInBytes = true, expectedRowCounts = Some(500))
+
+      withTempDir { tmpDir =>
+        val path = tmpDir.getCanonicalPath
+        sql(s"ALTER TABLE $textTable SET LOCATION '$path'")
+        checkStats(
+          textTable,
+          isDataSourceTable = false,
+          hasSizeInBytes = false,
+          expectedRowCounts = None)
+      }
+    }
+  }
+
   test("test table-level statistics for data source table created in HiveExternalCatalog") {
     val parquetTable = "parquetTable"
     withTable(parquetTable) {