diff --git a/constraints.txt b/constraints.txt
new file mode 100644
index 0000000..6194dab
--- /dev/null
+++ b/constraints.txt
@@ -0,0 +1,6 @@
+# because Python embeded with Galaxy is compiled with old openssl 1.1.0j which
+# is not compatibile with urllib3 2.0.0
+urllib3<2.0
+# toga dependency that caused error since version 3.0
+# possible to be fixed with a toga upgrade
+pythonnet<3
\ No newline at end of file
diff --git a/requirements.txt b/requirements.txt
index 579a175..d991adf 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -1,3 +1,4 @@
+-c constraints.txt
 galaxy.plugin.api==0.65
 sentry-sdk==1.5.8
 psutil==5.6.6