RxnID reaction Name Slope gene Reaction formula 'r_0173' "'aldehyde dehydrogenase (acetaldehyde, NADP)'" 1.882949481 'YPL061W' 'acetaldehyde[c] + H2O[c] + NADP(+)[c] + 5.5981 prot_P54115[c] => acetate[c] + 2 H+[c] + NADPH[c]' 'r_0959_EXP_1' 'pyruvate decarboxylase' 1.376670968 'YGR087C' 'H+[c] + pyruvate[c] + 0.26316 prot_P26263[c] => acetaldehyde[c] + carbon dioxide[c]' 'r_0961' 'pyruvate dehydrogenase' 0.71407914 'YBR221C and YER178W and YFL018C and YGR193C and YNL071W' '''coenzyme A[m] + NAD[m] + pyruvate[m] + 0.31585 prot_P09624[c] + 0.15151 prot_P12695[c] + 0.27101 prot_P16387[c] + 0.13264 prot_P...'' ' 'r_0962_EXP_1' 'pyruvate kinase' 0.66879413 'YAL038W' 'ADP[c] + H+[c] + phosphoenolpyruvate[c] + 0.065308 prot_P00549[c] => ATP[c] + pyruvate[c]' 'r_0300_EXP_2' 'citrate synthase' 0.627260514 'YPR001W' 'acetyl-CoA[m] + H2O[m] + oxaloacetate[m] + 0.10579 prot_P43635[c] => citrate[m] + coenzyme A[m] + H+[m]' 'r_0713' 'malate dehydrogenase' 0.627260514 'YKL085W' '(S)-malate[m] + NAD[m] + 0.05201 prot_P17505[c] => H+[m] + NADH[m] + oxaloacetate[m]' 'r_0366_EXP_4' 'enolase' 0.614038608 'YMR323W' '2-phospho-D-glyceric acid[c] + 0.67745 prot_P42222[c] => H2O[c] + phosphoenolpyruvate[c]' 'r_0893_EXP_1' 'phosphoglycerate mutase' 0.614038608 'YOR283W' '3-phosphonato-D-glycerate(3-)[c] + 7.4932 prot_Q12040[c] => 2-phospho-D-glyceric acid[c]' 'r_4262' 'citrate hydroxymutase' 0.593526763 'YJL200C' 'citrate[m] + 0.18549 prot_P39533[c] => isocitrate[m]' 'r_1021_EXP_2' 'succinate dehydrogenase (ubiquinone-6)' 0.540260207 'YDR178W and YKL141W and YKL148C and YLL041C' '''succinate[m] + ubiquinone-6[m] + 0.038292 prot_P21801[c] + 0.027953 prot_P33421[c] + 0.025649 prot_P37298[c] + 0.088956 prot_Q00...'' ' 'r_0486_EXP_1' 'glyceraldehyde-3-phosphate dehydrogenase' 0.530549945 'YGR192C' "'glyceraldehyde 3-phosphate[c] + NAD[c] + phosphate[c] + 1.0912 prot_P00359[c] => 1,3-bisphospho-D-glycerate[c] + H+[c] + NADH[c]'" 'r_0892' 'phosphoglycerate kinase' 0.530549945 'YCR012W' "'1,3-bisphospho-D-glycerate[c] + ADP[c] + 0.035105 prot_P00560[c] => 3-phosphonato-D-glycerate(3-)[c] + ATP[c]'" 'r_0148_EXP_2' 'adenylate kinase' 0.488099146 'YDR226W' 'AMP[c] + ATP[c] + 0.0076606 prot_P07170[c] => 2 ADP[c]' 'r_0467' 'glucose-6-phosphate isomerase' 0.467806412 'YBR196C' 'D-glucose 6-phosphate[c] + 0.024858 prot_P12709[c] => D-fructose 6-phosphate[c]' 'r_0450' 'fructose-bisphosphate aldolase' 0.425335766 'YKL060C' "'D-fructose 1,6-bisphosphate[c] + 0.16932 prot_P14540[c] => dihydroxyacetone phosphate[c] + glyceraldehyde 3-phosphate[c]'" 'r_0886' 'phosphofructokinase' 0.425335766 'YGR240C and YMR205C' "'''ATP[c] + D-fructose 6-phosphate[c] + 0.18686 prot_P16861[c] + 0.18106 prot_P16862[c] => ADP[c] + D-fructose 1,6-bisphosphate[c] ...'' '" 'r_1054' 'triose-phosphate isomerase' 0.316170318 'YDR050C' 'dihydroxyacetone phosphate[c] + 0.014886 prot_P00942[c] => glyceraldehyde 3-phosphate[c]' 'r_0982' 'ribose-5-phosphate isomerase' 0.158079813 'YOR095C' 'D-ribulose 5-phosphate[c] + 0.13203 prot_Q12189[c] => ribose-5-phosphate[c]' 'r_0811' 'nucleoside-diphosphate kinase (ATP:UDP)' 0.100792219 'YKL067W' 'ATP[c] + UDP[c] + 0.0022871 prot_P36010[c] => ADP[c] + UTP[c]' 'r_0888_EXP_2' 'phosphoglucomutase' 0.097582897 'YKL127W' 'D-glucose 6-phosphate[c] + 0.0746 prot_P33401[c] => D-glucose 1-phosphate[c]' 'r_1084_EXP_2' 'UTP-glucose-1-phosphate uridylyltransferase' 0.097582897 'YKL035W' 'D-glucose 1-phosphate[c] + H+[c] + UTP[c] + 0.57601 prot_P32861[c] => diphosphate[c] + UDP-D-glucose[c]' 'r_0112_EXP_1' 'acetyl-CoA synthetase' 0.091558917 'YAL054C' 'acetate[c] + ATP[c] + coenzyme A[c] + 0.3523 prot_Q01574[c] => acetyl-CoA[c] + AMP[c] + diphosphate[c]' 'r_0476' 'glutamine synthetase' 0.087668494 'YPR035W' 'ammonium[c] + ATP[c] + L-glutamate[c] + 0.22015 prot_P32288[c] => ADP[c] + H+[c] + L-glutamine[c] + phosphate[c]' 'r_0109' "'acetyl-CoA carboxylase, reaction'" 0.077110917 'YNR016C' 'acetyl-CoA[c] + ATP[c] + bicarbonate[c] + 2.7817 prot_Q00955[c] => ADP[c] + H+[c] + malonyl-CoA[c] + phosphate[c]' 'r_2131' 'isocitrate dehydrogenase' 0.068420785 'YDL066W' 'isocitrate[m] + NADP(+)[m] + 0.47808 prot_P21954[c] => 2-oxoglutarate[m] + carbon dioxide[m] + NADPH[m]' 'r_0800' 'nucleoside diphosphate kinase' 0.062080994 'YKL067W' 'ATP[c] + GDP[c] + 0.0022871 prot_P36010[c] => ADP[c] + GTP[c]' 'r_0714_REV' "'malate dehydrogenase, cytoplasmic (reversible)'" 0.056820053 'YOL126C' 'H+[c] + NADH[c] + oxaloacetate[c] + 9.3044e-05 prot_P22133[c] => (S)-malate[c] + NAD[c]' 'r_0005_EXP_3' "'1,3-beta-glucan synthase'" 0.048750191 'YPR165W and YMR306W' 'UDP-D-glucose[c] + 2.2611 prot_P06780[c] + 20.263 prot_Q04952[c] => (1->3)-beta-D-glucan[ce] + H+[c] + UDP[c]' 'r_0502' 'glycine hydroxymethyltransferase' 0.048239999 'YLR058C' "'L-serine[c] + THF[c] + 0.022664 prot_P37291[c] => 5,10-methylenetetrahydrofolate[c] + H2O[c] + L-glycine[c]'" 'r_0361' 'dolichyl-phosphate D-mannosyltransferase' 0.046302939 'YPR183W' 'dolichyl phosphate[c] + GDP-alpha-D-mannose[c] + 0.11895 prot_P14020[c] => dolichyl D-mannosyl phosphate[er] + GDP[c] + H+[c]' 'r_0362_EXP_1' 'dolichyl-phosphate-mannose--protein mannosyltransferase' 0.046302939 'YAL023C and YDL095W' 'dolichyl D-mannosyl phosphate[er] + 0.34035 prot_P31382[c] + 0.36309 prot_P33775[c] => dolichyl phosphate[er] + mannan[er]' 'r_0722' 'mannose-1-phosphate guanylyltransferase' 0.046302939 'YDL055C' 'D-mannose 1-phosphate[c] + GTP[c] + H+[c] + 0.27274 prot_P41940[c] => diphosphate[c] + GDP-alpha-D-mannose[c]' 'r_0723_REV' 'mannose-6-phosphate isomerase (reversible)' 0.046302939 'YER003C' 'D-fructose 6-phosphate[c] + 0.094935 prot_P29952[c] => D-mannose 6-phosphate[c]' 'r_0902_REV' 'phosphomannomutase (reversible)' 0.046302939 'YFL045C' 'D-mannose 6-phosphate[c] + 2.9511 prot_P07283[c] => D-mannose 1-phosphate[c]' 'r_0916_EXP_5' 'phosphoribosylpyrophosphate synthetase' 0.043159767 'YBL068W and YOL061W' 'ATP[c] + ribose-5-phosphate[c] + 0.24028 prot_P38063[c] + 0.35992 prot_Q12265[c] => AMP[c] + H+[c] + PRPP[c]' 'r_0096' 'acetohydroxy acid isomeroreductase' 0.041982102 'YLR355C' "'2-acetyllactic acid[m] + H+[m] + NADPH[m] + 0.67347 prot_P06168[c] => (R)-2,3-dihydroxy-3-methylbutanoate[m] + NADP(+)[m]'" 'r_0097_EXP_1' 'acetolactate synthase' 0.041982102 'YCL009C and YMR108W' 'H+[m] + 2 pyruvate[m] + 0.34406 prot_P07342[c] + 0.15605 prot_P25605[c] => 2-acetyllactic acid[m] + carbon dioxide[m]' 'r_0352' "'dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylbutanoate)'" 0.041982102 'YJR016C' "'(R)-2,3-dihydroxy-3-methylbutanoate[m] + 5.2245 prot_P39522[c] => 3-methyl-2-oxobutanoate[m] + H2O[m]'" 'r_0452' "'fumarase, cytoplasmic'" 0.041606044 'YPL262W' 'fumarate[c] + H2O[c] + 0.014265 prot_P08417[c] => (S)-malate[c]'