diff --git a/CHANGELOG.rst b/CHANGELOG.rst
index ac713b8a7c..28be6f0c86 100644
--- a/CHANGELOG.rst
+++ b/CHANGELOG.rst
@@ -37,6 +37,9 @@ Changed
 
   Contributed by @Kami and @shital.
 
+* Import ABC from collections.abc for Python 3.10 compatibility. (#5007)
+  Contributed by @tirkarthi
+
 3.4.0 - March 02, 2021
 ----------------------
 
diff --git a/st2client/st2client/utils/types.py b/st2client/st2client/utils/types.py
index ad70f078b9..98298119c7 100644
--- a/st2client/st2client/utils/types.py
+++ b/st2client/st2client/utils/types.py
@@ -18,12 +18,12 @@
 """
 
 from __future__ import absolute_import
-import collections
+from collections.abc import MutableSet
 
 __all__ = ["OrderedSet"]
 
 
-class OrderedSet(collections.MutableSet):
+class OrderedSet(MutableSet):
     def __init__(self, iterable=None):
         self.end = end = []
         end += [None, end, end]  # sentinel node for doubly linked list
diff --git a/st2common/st2common/util/db.py b/st2common/st2common/util/db.py
index 09191e0c28..2ead2c81cd 100644
--- a/st2common/st2common/util/db.py
+++ b/st2common/st2common/util/db.py
@@ -15,10 +15,11 @@
 
 from __future__ import absolute_import
 
-import collections
 import mongoengine
 import six
 
+from collections.abc import Mapping
+
 
 def mongodb_to_python_types(value):
     # Convert MongoDB BaseDict and BaseList types to python dict and list types.
@@ -30,7 +31,7 @@ def mongodb_to_python_types(value):
     # functions used to convert JSON/YAML objects/strings will errored. This is caused
     # by the PR StackStorm/orquesta#191 which converts dict to collections.Mapping
     # in YAQL related functions.
-    elif isinstance(value, collections.Mapping):
+    elif isinstance(value, Mapping):
         value = dict(value)
 
     # Recursively traverse the dict and list to convert values.
diff --git a/st2common/st2common/util/misc.py b/st2common/st2common/util/misc.py
index 6a1027e9fe..8c73e1332c 100644
--- a/st2common/st2common/util/misc.py
+++ b/st2common/st2common/util/misc.py
@@ -20,10 +20,10 @@
 import os
 import re
 import sys
-import collections
 import functools
 
 import six
+from collections.abc import Mapping
 
 __all__ = [
     "prefix_dict_keys",
@@ -137,7 +137,7 @@ def deep_update(d, u):
     """
 
     for k, v in six.iteritems(u):
-        if isinstance(v, collections.Mapping):
+        if isinstance(v, Mapping):
             r = deep_update(d.get(k, {}), v)
             d[k] = r
         else:
diff --git a/st2common/st2common/util/pack.py b/st2common/st2common/util/pack.py
index 43dde60051..4dadba87cb 100644
--- a/st2common/st2common/util/pack.py
+++ b/st2common/st2common/util/pack.py
@@ -17,10 +17,10 @@
 
 import os
 import re
-import collections
 
 import six
 
+from collections.abc import Iterable
 from st2common.util import schema as util_schema
 from st2common.constants.pack import MANIFEST_FILE_NAME
 from st2common.constants.pack import PACK_REF_WHITELIST_REGEX
@@ -167,7 +167,7 @@ def validate_config_against_schema(
     except jsonschema.ValidationError as e:
         attribute = getattr(e, "path", [])
 
-        if isinstance(attribute, (tuple, list, collections.Iterable)):
+        if isinstance(attribute, (tuple, list, Iterable)):
             attribute = [str(item) for item in attribute]
             attribute = ".".join(attribute)
         else:
diff --git a/st2common/st2common/util/types.py b/st2common/st2common/util/types.py
index ad70f078b9..98298119c7 100644
--- a/st2common/st2common/util/types.py
+++ b/st2common/st2common/util/types.py
@@ -18,12 +18,12 @@
 """
 
 from __future__ import absolute_import
-import collections
+from collections.abc import MutableSet
 
 __all__ = ["OrderedSet"]
 
 
-class OrderedSet(collections.MutableSet):
+class OrderedSet(MutableSet):
     def __init__(self, iterable=None):
         self.end = end = []
         end += [None, end, end]  # sentinel node for doubly linked list