-
Notifications
You must be signed in to change notification settings - Fork 5
/
1218.tumor.suppressor.gene.txt
1217 lines (1217 loc) · 7.48 KB
/
1218.tumor.suppressor.gene.txt
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
478
479
480
481
482
483
484
485
486
487
488
489
490
491
492
493
494
495
496
497
498
499
500
501
502
503
504
505
506
507
508
509
510
511
512
513
514
515
516
517
518
519
520
521
522
523
524
525
526
527
528
529
530
531
532
533
534
535
536
537
538
539
540
541
542
543
544
545
546
547
548
549
550
551
552
553
554
555
556
557
558
559
560
561
562
563
564
565
566
567
568
569
570
571
572
573
574
575
576
577
578
579
580
581
582
583
584
585
586
587
588
589
590
591
592
593
594
595
596
597
598
599
600
601
602
603
604
605
606
607
608
609
610
611
612
613
614
615
616
617
618
619
620
621
622
623
624
625
626
627
628
629
630
631
632
633
634
635
636
637
638
639
640
641
642
643
644
645
646
647
648
649
650
651
652
653
654
655
656
657
658
659
660
661
662
663
664
665
666
667
668
669
670
671
672
673
674
675
676
677
678
679
680
681
682
683
684
685
686
687
688
689
690
691
692
693
694
695
696
697
698
699
700
701
702
703
704
705
706
707
708
709
710
711
712
713
714
715
716
717
718
719
720
721
722
723
724
725
726
727
728
729
730
731
732
733
734
735
736
737
738
739
740
741
742
743
744
745
746
747
748
749
750
751
752
753
754
755
756
757
758
759
760
761
762
763
764
765
766
767
768
769
770
771
772
773
774
775
776
777
778
779
780
781
782
783
784
785
786
787
788
789
790
791
792
793
794
795
796
797
798
799
800
801
802
803
804
805
806
807
808
809
810
811
812
813
814
815
816
817
818
819
820
821
822
823
824
825
826
827
828
829
830
831
832
833
834
835
836
837
838
839
840
841
842
843
844
845
846
847
848
849
850
851
852
853
854
855
856
857
858
859
860
861
862
863
864
865
866
867
868
869
870
871
872
873
874
875
876
877
878
879
880
881
882
883
884
885
886
887
888
889
890
891
892
893
894
895
896
897
898
899
900
901
902
903
904
905
906
907
908
909
910
911
912
913
914
915
916
917
918
919
920
921
922
923
924
925
926
927
928
929
930
931
932
933
934
935
936
937
938
939
940
941
942
943
944
945
946
947
948
949
950
951
952
953
954
955
956
957
958
959
960
961
962
963
964
965
966
967
968
969
970
971
972
973
974
975
976
977
978
979
980
981
982
983
984
985
986
987
988
989
990
991
992
993
994
995
996
997
998
999
1000
ACHE
ACY1
ADARB1
ADPRH
PARP1
AGTR1
AHR
AIF1
AKR1B1
ALOX15
ALOX15B
ALPL
AMH
BIN1
ANXA1
ANXA7
APAF1
APC
FAS
ARF1
ARG1
RHOA
RHOB
RND3
PHOX2A
ARNTL
ASCL1
ASS1
ZFHX3
ATF3
ATM
ATR
AZGP1
BARD1
BAX
BCR
CEACAM1
BIK
PRDM1
BLM
BMP2
BMP4
BMPR1A
BMPR2
BNIP3L
FOXL2
BRCA1
BRCA2
ZFP36L2
KLF5
BTK
CAPG
CASP2
CASP5
CASP8
CAT
CAV1
RUNX2
RUNX1
CBFA2T3
RUNX3
CBL
KRIT1
CCNC
CD4
CD44
CDH1
CDH4
CDH5
CDH11
CDH13
CDH17
CDK2
CDK6
CDKN1A
CDKN1B
CDKN1C
CDKN2A
CDKN2B
CDKN2C
CDO1
CDX2
CEBPA
CEBPD
CFTR
CHD1
CHEK1
CHUK
CLU
CNN1
KLF6
MAP3K8
CREBBP
CREM
CSF2
CSNK1A1
CST5
CST6
CTGF
CTNNA2
CTNND1
CUX1
CYB5A
CYLD
DAB2
DACH1
DAPK1
DAPK3
BRINP1
DCC
DCN
DDB2
GADD45A
DDX3X
DEFB1
DFFA
DFNA5
DLG1
DMBT1
DMD
DNMT1
DNMT3A
DNMT3B
DOK1
DPH1
DPP4
DSC3
DSP
DUSP1
DUSP5
DUSP6
DUSP9
E2F1
E2F2
E2F3
ECT2
EDNRB
EEF1A1
EFNA5
EGR1
EGR2
EPHA2
EMP1
EMP2
EPAS1
EPB41
EPHA1
EPHA3
EPHB2
EPHB3
EPHB4
EPHB6
ERBB4
EYA4
ERF
ESR1
ESR2
ESRRB
ETS2
ETV6
EXT1
EXT2
EXTL1
EXTL2
EXTL3
EZH1
EZH2
FABP3
FANCG
FBLN1
FAT1
FBP1
GPC5
FH
FHIT
FHL1
FOXC1
FOXO1
FOXO3
FLNA
FLT3
FXN
FRK
FUS
GALR1
GAS1
GATA4
GBP1
GJA1
GJB2
GPC3
GLI1
GNAT1
SFN
GPX3
GRIN2A
GSK3B
GSN
GSTP1
GSTT1
BRF1
GUCY2C
H2AFX
HDAC1
HIC1
HIF1A
HINT1
HIVEP1
ZBTB48
NR4A1
FOXA1
FOXA2
HNF4A
ONECUT1
HPGD
HRG
HSPD1
DNAJB1
IRF8
ID4
IDH1
IFI16
IGF1
IGF2R
IGFALS
IGFBP3
IGFBP4
IGFBP5
IGFBP7
CXCR2
IL17A
ILK
ING1
ING2
CXCL10
PDX1
IRF1
IRF3
IRF4
IRF5
ITGA5
ITGA7
ITGAV
ITGB1
ITGB3
JUP
CD82
KISS1
KRT19
LGALS7
LIFR
LLGL1
VWA5A
LOX
LRMP
LSAMP
LTF
MARCKS
SMAD2
SMAD4
MAL
MAT2A
MAX
MCC
MAP3K4
MEN1
MLH1
FOXO4
MME
MNT
MSH2
MSMB
MST1
MST1R
MT1F
MT1G
MT1M
MT2A
MTAP
MXI1
GADD45B
MYH9
MYO1A
NBN
NDN
NEDD4
NF1
NF2
NFATC2
NFKB1
NGFR
NINJ1
NKX3-1
NNAT
NME1
CNOT3
NOTCH1
NOTCH2
NOTCH3
NOV
NPAS2
NPM1
NRCAM
NRF1
NTRK3
ROR2
DDR2
NUP98
OPCML
PEBP1
PAEP
PAFAH1B1
PARK2
PAWR
PAX4
PAX5
PAX6
PCDHGC3
PCDH8
PCDH9
PDGFRL
PEG3
PF4
PFN1
PGR
PHB
SERPINB5
SERPINI2
PIN1
PKD1
PKNOX1
PLA2G2A
PLAGL1
PLCB3
PLCD1
PLD1
PLK1
PML
PNN
4-Sep
PPARA
PPARG
PPM1A
PPP1CA
PPP2CA
PPP2CB
PPP2R1B
PPP2R2C
PPP2R4
PPP2R5C
PPP3CC
PRKAA1
PRKAA2
PRKAR1A
PRKCB
PRKCD
PRKCE
MAPK9
MAPK10
PRODH
PROX1
KLK6
HTRA1
KLK10
PTCH1
PTEN
PTGDR
PTPN1
PTPN2
PTPN6
PTPN11
PTPN12
PTPN13
PTPRC
PTPRD
PTPRJ
PTPRK
RAD23B
RAD51C
RAP1A
RAP1GAP
RARB
RARRES3
RB1
KDM5A
RBBP7
RBBP8
RBL1
RBL2
RBM4
RBP1
RNASEL
RNH1
ROBO1
RPA1
RPL5
RPL10
RPL11
RPS6KA2
S100A2
S100A11
SAA1
SAFB
SALL2
CXCL12
SDHA
SDHB
SDHD
SEMA3F
MAP2K4
SFRP1
SFRP2
SFRP4
SFRP5
SIAH1
SKIL
SKP2
SMARCA2
HLTF
SMARCA4
SMARCB1
SMARCC1
SOD2
SOX1
SOX11
SOX15
SP100
SPARC
SPI1
SPTBN1
ST5
ST13
STAT1
STAT3
STAT5A
STK10
STK11
SYK
TAGLN
TAT
TBX5
TCEB3
TCF4
TCF3
TCF7L2
TDGF1
TFAP2A
TGFB1
LEFTY2
TGFBI
TGFBR2
TGFBR3
TGM3
THBD
THBS1
THRA
THRB
THY1
KLF10
TIMP3
TNFAIP3
TP53
TP53BP1
TP53BP2
TP73
NR2C2
HSP90B1
TSC1
TSC2
TSG101
PHLDA2
TTC4
TTF1
HIRA
UCHL1
KDM6A
UVRAG
VDR
VEGFA
VHL
VIL1
VIM
VSNL1
LAT2
WNT5A
WNT7A
WNT11
WT1
XRCC5
ZFP36
ZIC1
PCGF2
ZBTB16
ZNF185
ZYX
PRDM2
BTG2
SEMA3B
RAB7A
PLA2G7
AIMP2
TFPI2
ST7
NR4A3
NCOA4
CUL5
CDK2AP1
IFT88
ANP32A
MIA
ARID1A
AXIN1
AXIN2
BAP1
MAD1L1
SPARCL1
SPOP
SRPX
NR0B2
RECK
RASAL1
CUL2
CUL1
PIAS1
MADD
PDLIM4
TMEFF1
TP63
UNC5C
RNASET2
PTCH2
NUMB
SOCS1
EIF3F
BECN1
PEA15
TNK1
EED
TNFSF12
TNFSF9
FADD
TNFRSF18
DLK1
TNFRSF10B
TNFRSF10A
TRIM24
INPP4B
WISP3
HDAC3
DLEU2
TSC22D1
ALDH1A2
NR1I2
PER2
IER3
BCL10
MBD4
SELENBP1
LIMD1
SOCS3
RNF8
DOK2
AIP
GPRC5A
CLDN1
DIRAS3
DNAJA3
LATS1
PDCD5
NEURL1
AIMP1
KLF4
COPS2
SLIT2
KL
SLC9A3R1
ARHGAP29
ABCG2
AIM2
HOMER2
RASAL2
CHST10
LITAF
EEF1E1
EI24
CXCL14
AKAP12
ISG15
MDC1
SAFB2
RASSF2
RNF144A
MTSS1
RB1CC1
NUAK1
SRGAP3
DCLRE1A
DLEC1
DMTF1
TANK
BCL2L11
SH2B3
RANBP9
TSPAN32
TSSC4
ABI2
PLXNC1
RBM6
RBM5
TRIM13
TOPORS
CTDSPL
SPRY2
STUB1
UBE4B
DLEU1
IKZF1
MRVI1
CITED2
DLC1
NDRG1
GNB2L1
BASP1
YAP1
PGRMC2
RBM14
ZBTB18
HOXB13
MYBBP1A
KAT5
ARL6IP5
HTATIP2
OLFM4
TRIM3
TXNIP
RASL10A
LEFTY1
NPRL2
SPINT2
CTCF
AHCYL1
PLK2
ZMYND11
IQGAP2
FRS3
BLCAP
GADD45G
BTG3
IL24
GLIPR1
CYB561D2
TRIM31
DNAJB4
DIDO1
ADAMTS8
PRDM5
PRDM4
PTPRT
PLA2G16
LZTS1
MAP4K1
RASSF1
PTENP1
WIF1
CHEK2
TREX2
RASSF8
POU6F2
PARK7
TUSC2
GABARAP
IKZF3
IKZF2
ZHX2
PLA2R1
SIRT2
DKK1
TRIM32
USP33
PHLPP2
ZNF292
PDS5B
TRIM35
KIF1B
EPB41L3
CIC
KANK1
GANAB
RHOBTB2
PHLPP1
CAMTA1
ATMIN
NEDD4L
SASH1
SYNM
SMCHD1
ARHGEF12
UFL1
DICER1
SIRT4
SIRT3
SIRT1
CBX5
SUZ12
SCRIB
SEC14L2
GTPBP4
CCNDBP1
DDX58
DAPK2
PHLDA3
SSBP2
TMEFF2
CADM1
CIZ1
POU2F3
BRMS1
RCHY1
PTPN23
LRIG1
CHD5
CNTNAP2
TES
NKX2-8
FBXO25
EHF
LHX6
NUPR1
INTS6
LATS2
GREM1
TBL2
SNORD50A
HBP1
FOXD3
MLH3
TSPAN13
FOXP1
BBC3
DKK3
HSPB7
CPNE7
GLS2
SLC39A1
GNMT
PDCD4
PCDH17
BMP10
RBMS3
RBMX
RPS6KA6
HTRA2
HIPK2
SETD2
PYCARD
BRD7
CTNNA3
BLNK
UBIAD1
OSGIN1
NRBP1
GLTSCR2
GLTSCR1
EHD3
CRNN
G0S2
1-Dec
FOXP3
SH3GLB1
ANGPTL4
ING4
PLEKHO1
PLCE1
ZDHHC2
MZB1
PAIP2
TNFRSF12A
DACT1
FZR1
ZMYND10
NOL7
DCDC2
LIMA1
CXXC5
SIRT6
SUFU
HECA
CYB5R2
UIMC1
WWOX
KDM3B
LRP1B
ERRFI1
ING3
EGLN1
XAF1
IL17RD
BTG4
RNF111
TET2
TRIT1
ESRP1
WHSC1L1
BANP
HRASLS2
PINX1
PIWIL2
SHQ1
PBRM1
TRIM62
MOB1A
CASC1
VPS53
FBXW7
MEG3
CAMK2N1
RBM38
VEZT
PRR5
SLC39A4
TMEM127
WDR11
DNAJC11
CHFR
CNDP2
CCAR1
CACNA2D3
KDM3A
EAF2
THSD1
AJAP1
GKN1
RPRM
DIABLO
PANX2
TCEAL7
LXN
DUSP22
NIT2
PRDM11
CTNNBIP1
ADAMTS9
PDSS2
RAB25
RTN4
SALL4
SCYL1
NDRG2
AHRR
MTUS1
XPO5
HACE1
PCDH10
SYT13
WDR48
ZBTB4
NCOA5
SCUBE2
CCAR2
CADM3
WFDC1
KMT2C
HIVEP3
EDA2R
RINT1
GAS5
BCORL1
LRRC4
RFWD2
CSMD1
NDST4
CSRNP1
ANAPC1
CCDC136
CDCP1
NDRG4
WNK2
PHACTR4
DUSP26
AHNAK
IRX1
BHLHE41
CDC73
TNFAIP8L2
FAT4
MCPH1
PALB2
ZNF668
FBXO31
ARMC5
KDM8
GGNBP2
DOK3
DENND2D
PHC3
FAM188A
NRSN2
MUS81
CXXC4
SPRY4
RASSF5
SOX7
YPEL3
MARVELD1
ARMC10
RASSF4
FAM172A
PPP1R1B
TCHP
ING5
PHF6
C2orf40
BRSK1
SLX4
HOPX
AFAP1L2
SPINK7
MYO18B
BEX2
RTN4IP1
ZC3H10
MFSD2A
TBRG1
ZNF382
RITA1
EAF1
TSLP
TRIM15
LHX4
UNC5A
BMF
GADD45GIP1
STARD13
CREB3L1
L3MBTL4
RASL10B
CABLES1
SCGB3A1
STRADA
GORAB
MOB1B
TPTE2
HTRA3
TP53INP1
EGLN3
PRKCDBP
CYGB
SMYD4
FBXO32
UHRF2
ARL11
BATF2
LRRC3B
CMTM5
MIA2
TWIST2
LRIG3
JDP2
DCUN1D3
CMTM3
PLK5
OSCP1
ACVR1C
UBE2QL1
PACRG
CLDN23
UNC5D
AMER1
GATA5
CTCFL
PRICKLE1
TOM1L2
DIRAS1
PYHIN1
SIK1
PPM1L
SHISA3
DAB2IP
CCDC67
LMNTD1
SLC5A8
TMPRSS6
ZNF366
ADAMTS18
ASXL1
SYNPO2
ARID2
CADM4
GKN2
FLCN
ZBTB7C
SAMD9L
USP12
UNC5B
HEPACAM
FBXL13
NAPEPLD
CADM2
EBF3
MCM9