diff --git a/docs/src/common_links.inc b/docs/src/common_links.inc
index d9df15be8b..fcd66e0017 100644
--- a/docs/src/common_links.inc
+++ b/docs/src/common_links.inc
@@ -28,6 +28,7 @@
 .. _Read the Docs: https://scitools-iris.readthedocs.io/en/latest/
 .. _readthedocs.yml: https://github.com/SciTools/iris/blob/master/requirements/ci/readthedocs.yml
 .. _SciTools: https://github.com/SciTools
+.. _scitools-iris: https://pypi.org/project/scitools-iris/
 .. _sphinx: https://www.sphinx-doc.org/en/master/
 .. _test-iris-imagehash: https://github.com/SciTools/test-iris-imagehash
 .. _using git: https://docs.github.com/en/github/using-git
diff --git a/docs/src/developers_guide/release.rst b/docs/src/developers_guide/release.rst
index 90938b32d3..0802d5de22 100644
--- a/docs/src/developers_guide/release.rst
+++ b/docs/src/developers_guide/release.rst
@@ -1,3 +1,5 @@
+.. include:: ../common_links.inc
+
 .. _iris_development_releases:
 
 Releases
@@ -82,14 +84,59 @@ Once all checks are complete, the release is cut by the creation of a new tag
 in the ``SciTools/iris`` repository.
 
 
-Conda Recipe
-------------
+Update conda-forge
+------------------
 
 Once a release is cut on GitHub, update the Iris conda recipe on the
 `conda-forge iris-feedstock`_ for the release. This will build and publish the
 conda package on the `conda-forge Anaconda channel`_.
 
 
+.. _update_pypi:
+
+Update PyPI
+-----------
+
+Update the `scitools-iris`_ project on PyPI with the latest Iris release.
+
+To do this perform the following steps.
+
+Create a conda environment with the appropriate conda packages to build the
+source distribution (``sdist``) and pure Python wheel (``bdist_wheel``)::
+
+    > conda create -n iris-pypi -c conda-forge --yes pip pyke python setuptools twine wheel
+    > . activate iris-pypi
+
+Checkout the lastest Iris ``<release>`` tag::
+
+    > git fetch --tags
+    > git checkout <release>
+
+Build the source distribution and wheel from the Iris root directory::
+
+    > python setup.py sdist bdist_wheel
+
+This ``./dist`` directory should now be populated with the source archive
+``.tar.gz`` file, and built distribution ``.whl`` file.
+
+Sufficient maintainer privileges will be required to upload these artifacts
+to `scitools-iris`_ on PyPI::
+
+    > python -m twine upload --repository-url https://upload.pypi.org/legecy/ ./dist/*
+
+Ensure that the artifacts are successfully uploaded and available on
+`scitools-iris`_ before creating a conda test environment to install Iris
+from PyPI::
+
+    > conda deactivate
+    > conda env create --file ./requrements/ci/iris.yml
+    > . activate iris-dev
+    > conda install -c conda-forge pip
+    > python -m pip install --no-deps scitools-iris
+
+For futher details on how to test Iris, see :ref:`developer_running_tests`.
+
+
 Merge Back
 ----------
 
@@ -179,7 +226,6 @@ Post Release Steps
 #. Merge back to ``master``
 
 
-.. _Read The Docs: https://readthedocs.org/projects/scitools-iris/builds/
 .. _SciTools/iris: https://github.com/SciTools/iris
 .. _tag on the SciTools/Iris: https://github.com/SciTools/iris/releases
 .. _conda-forge Anaconda channel: https://anaconda.org/conda-forge/iris
diff --git a/docs/src/whatsnew/latest.rst b/docs/src/whatsnew/latest.rst
index 6fcdcfb7bc..689a41ac53 100644
--- a/docs/src/whatsnew/latest.rst
+++ b/docs/src/whatsnew/latest.rst
@@ -106,6 +106,9 @@ This document explains the changes made to Iris for this release
    development documentation if being viewed on `Read the Docs`_.
    (:pull:`3999`)
 
+#. `@bjlittle`_ added post-release instructions on how to :ref:`update_pypi`
+   with `scitools-iris`_. (:pull:`4038`)
+
 
 💼 Internal
 ===========