diff --git a/src/GCModeller/data/KEGG/app.config b/src/GCModeller/data/KEGG/app.config
index 1157a93ac79..444a05c04a2 100644
--- a/src/GCModeller/data/KEGG/app.config
+++ b/src/GCModeller/data/KEGG/app.config
@@ -26,15 +26,15 @@
       </dependentAssembly>
       <dependentAssembly>
         <assemblyIdentity name="System.Buffers" publicKeyToken="cc7b13ffcd2ddd51" culture="neutral" />
-        <bindingRedirect oldVersion="0.0.0.0-4.0.3.0" newVersion="4.0.3.0" />
+        <bindingRedirect oldVersion="0.0.0.0-4.0.5.0" newVersion="4.0.5.0" />
       </dependentAssembly>
       <dependentAssembly>
         <assemblyIdentity name="System.Memory" publicKeyToken="cc7b13ffcd2ddd51" culture="neutral" />
-        <bindingRedirect oldVersion="0.0.0.0-4.0.1.1" newVersion="4.0.1.1" />
+        <bindingRedirect oldVersion="0.0.0.0-4.0.5.0" newVersion="4.0.5.0" />
       </dependentAssembly>
       <dependentAssembly>
         <assemblyIdentity name="Renci.SshNet" publicKeyToken="1cee9f8bde3db106" culture="neutral" />
-        <bindingRedirect oldVersion="0.0.0.0-2020.0.1.0" newVersion="2020.0.1.0" />
+        <bindingRedirect oldVersion="0.0.0.0-2026.0.0.1" newVersion="2026.0.0.1" />
       </dependentAssembly>
       <dependentAssembly>
         <assemblyIdentity name="BouncyCastle.Crypto" publicKeyToken="0e99375e54769942" culture="neutral" />
@@ -42,15 +42,15 @@
       </dependentAssembly>
       <dependentAssembly>
         <assemblyIdentity name="System.Threading.Tasks.Extensions" publicKeyToken="cc7b13ffcd2ddd51" culture="neutral" />
-        <bindingRedirect oldVersion="0.0.0.0-4.2.0.1" newVersion="4.2.0.1" />
+        <bindingRedirect oldVersion="0.0.0.0-4.2.4.0" newVersion="4.2.4.0" />
       </dependentAssembly>
       <dependentAssembly>
         <assemblyIdentity name="K4os.Compression.LZ4" publicKeyToken="2186fa9121ef231d" culture="neutral" />
-        <bindingRedirect oldVersion="0.0.0.0-1.2.6.0" newVersion="1.2.6.0" />
+        <bindingRedirect oldVersion="0.0.0.0-1.2.10.0" newVersion="1.2.10.0" />
       </dependentAssembly>
       <dependentAssembly>
         <assemblyIdentity name="System.Runtime.CompilerServices.Unsafe" publicKeyToken="b03f5f7f11d50a3a" culture="neutral" />
-        <bindingRedirect oldVersion="0.0.0.0-6.0.0.0" newVersion="6.0.0.0" />
+        <bindingRedirect oldVersion="0.0.0.0-6.0.3.0" newVersion="6.0.3.0" />
       </dependentAssembly>
       <dependentAssembly>
         <assemblyIdentity name="K4os.Compression.LZ4.Streams" publicKeyToken="2186fa9121ef231d" culture="neutral" />
diff --git a/src/GCModeller/data/KEGG/jp_kegg2.vbproj b/src/GCModeller/data/KEGG/jp_kegg2.vbproj
index e6f6587131f..b1f687581e2 100644
--- a/src/GCModeller/data/KEGG/jp_kegg2.vbproj
+++ b/src/GCModeller/data/KEGG/jp_kegg2.vbproj
@@ -212,6 +212,10 @@
     <Reference Include="BouncyCastle.Crypto, Version=1.8.9.0, Culture=neutral, PublicKeyToken=0e99375e54769942">
       <HintPath>..\..\..\packages\BouncyCastle.1.8.9\lib\BouncyCastle.Crypto.dll</HintPath>
     </Reference>
+    <Reference Include="BouncyCastle.Cryptography, Version=2.0.0.0, Culture=neutral, PublicKeyToken=072edcf4a5328938">
+      <HintPath>..\..\..\packages\BouncyCastle.Cryptography.2.7.0\lib\net461\BouncyCastle.Cryptography.dll</HintPath>
+      <Private>True</Private>
+    </Reference>
     <Reference Include="EntityFramework, Version=6.0.0.0, Culture=neutral, PublicKeyToken=b77a5c561934e089, processorArchitecture=MSIL">
       <HintPath>..\..\..\packages\EntityFramework.6.4.4\lib\net45\EntityFramework.dll</HintPath>
     </Reference>
@@ -230,19 +234,37 @@
     <Reference Include="K4os.Hash.xxHash, Version=1.0.6.0, Culture=neutral, PublicKeyToken=32cd54395057cec3, processorArchitecture=MSIL">
       <HintPath>..\..\..\packages\K4os.Hash.xxHash.1.0.6\lib\net46\K4os.Hash.xxHash.dll</HintPath>
     </Reference>
+    <Reference Include="Microsoft.Bcl.AsyncInterfaces, Version=10.0.0.11, Culture=neutral, PublicKeyToken=cc7b13ffcd2ddd51">
+      <HintPath>..\..\..\packages\Microsoft.Bcl.AsyncInterfaces.10.0.11\lib\net462\Microsoft.Bcl.AsyncInterfaces.dll</HintPath>
+      <Private>True</Private>
+    </Reference>
+    <Reference Include="Microsoft.Bcl.Cryptography, Version=10.0.0.11, Culture=neutral, PublicKeyToken=cc7b13ffcd2ddd51">
+      <HintPath>..\..\..\packages\Microsoft.Bcl.Cryptography.10.0.11\lib\net462\Microsoft.Bcl.Cryptography.dll</HintPath>
+      <Private>True</Private>
+    </Reference>
     <Reference Include="Microsoft.CSharp" />
+    <Reference Include="Microsoft.Extensions.DependencyInjection.Abstractions, Version=10.0.0.11, Culture=neutral, PublicKeyToken=adb9793829ddae60">
+      <HintPath>..\..\..\packages\Microsoft.Extensions.DependencyInjection.Abstractions.10.0.11\lib\net462\Microsoft.Extensions.DependencyInjection.Abstractions.dll</HintPath>
+      <Private>True</Private>
+    </Reference>
+    <Reference Include="Microsoft.Extensions.Logging.Abstractions, Version=10.0.0.11, Culture=neutral, PublicKeyToken=adb9793829ddae60">
+      <HintPath>..\..\..\packages\Microsoft.Extensions.Logging.Abstractions.10.0.11\lib\net462\Microsoft.Extensions.Logging.Abstractions.dll</HintPath>
+      <Private>True</Private>
+    </Reference>
     <Reference Include="MySql.Data, Version=8.0.25.0, Culture=neutral, PublicKeyToken=c5687fc88969c44d, processorArchitecture=MSIL">
       <HintPath>..\..\..\packages\MySql.Data.8.0.25\lib\net48\MySql.Data.dll</HintPath>
     </Reference>
     <Reference Include="mysql.data.entity.EF6, Version=6.8.3.0, Culture=neutral, PublicKeyToken=c5687fc88969c44d, processorArchitecture=MSIL">
       <HintPath>..\..\..\packages\MySql.Data.Entities.6.8.3.0\lib\net45\mysql.data.entity.EF6.dll</HintPath>
     </Reference>
-    <Reference Include="Renci.SshNet, Version=2020.0.1.0, Culture=neutral, PublicKeyToken=1cee9f8bde3db106, processorArchitecture=MSIL">
-      <HintPath>..\..\..\packages\SSH.NET.2020.0.1\lib\net40\Renci.SshNet.dll</HintPath>
+    <Reference Include="Renci.SshNet, Version=2026.0.0.1, Culture=neutral, PublicKeyToken=1cee9f8bde3db106">
+      <HintPath>..\..\..\packages\SSH.NET.2026.0.0\lib\net462\Renci.SshNet.dll</HintPath>
+      <Private>True</Private>
     </Reference>
     <Reference Include="System" />
-    <Reference Include="System.Buffers, Version=4.0.3.0, Culture=neutral, PublicKeyToken=cc7b13ffcd2ddd51, processorArchitecture=MSIL">
-      <HintPath>..\..\..\packages\System.Buffers.4.5.1\lib\net461\System.Buffers.dll</HintPath>
+    <Reference Include="System.Buffers, Version=4.0.5.0, Culture=neutral, PublicKeyToken=cc7b13ffcd2ddd51">
+      <HintPath>..\..\..\packages\System.Buffers.4.6.1\lib\net462\System.Buffers.dll</HintPath>
+      <Private>True</Private>
     </Reference>
     <Reference Include="System.ComponentModel" />
     <Reference Include="System.ComponentModel.DataAnnotations" />
@@ -250,16 +272,31 @@
     <Reference Include="System.Configuration.Install" />
     <Reference Include="System.Data" />
     <Reference Include="System.Data.Linq" />
+    <Reference Include="System.Diagnostics.DiagnosticSource, Version=10.0.0.11, Culture=neutral, PublicKeyToken=cc7b13ffcd2ddd51">
+      <HintPath>..\..\..\packages\System.Diagnostics.DiagnosticSource.10.0.11\lib\net462\System.Diagnostics.DiagnosticSource.dll</HintPath>
+      <Private>True</Private>
+    </Reference>
+    <Reference Include="System.Formats.Asn1, Version=10.0.0.11, Culture=neutral, PublicKeyToken=cc7b13ffcd2ddd51">
+      <HintPath>..\..\..\packages\System.Formats.Asn1.10.0.11\lib\net462\System.Formats.Asn1.dll</HintPath>
+      <Private>True</Private>
+    </Reference>
     <Reference Include="System.Management" />
-    <Reference Include="System.Memory, Version=4.0.1.1, Culture=neutral, PublicKeyToken=cc7b13ffcd2ddd51, processorArchitecture=MSIL">
-      <HintPath>..\..\..\packages\System.Memory.4.5.4\lib\net461\System.Memory.dll</HintPath>
+    <Reference Include="System.Memory, Version=4.0.5.0, Culture=neutral, PublicKeyToken=cc7b13ffcd2ddd51">
+      <HintPath>..\..\..\packages\System.Memory.4.6.3\lib\net462\System.Memory.dll</HintPath>
+      <Private>True</Private>
     </Reference>
     <Reference Include="System.Numerics" />
-    <Reference Include="System.Numerics.Vectors, Version=4.1.4.0, Culture=neutral, PublicKeyToken=b03f5f7f11d50a3a, processorArchitecture=MSIL">
-      <HintPath>..\..\..\packages\System.Numerics.Vectors.4.5.0\lib\net46\System.Numerics.Vectors.dll</HintPath>
+    <Reference Include="System.Numerics.Vectors, Version=4.1.6.0, Culture=neutral, PublicKeyToken=b03f5f7f11d50a3a">
+      <HintPath>..\..\..\packages\System.Numerics.Vectors.4.6.1\lib\net462\System.Numerics.Vectors.dll</HintPath>
+      <Private>True</Private>
+    </Reference>
+    <Reference Include="System.Runtime.CompilerServices.Unsafe, Version=6.0.3.0, Culture=neutral, PublicKeyToken=b03f5f7f11d50a3a">
+      <HintPath>..\..\..\packages\System.Runtime.CompilerServices.Unsafe.6.1.2\lib\net462\System.Runtime.CompilerServices.Unsafe.dll</HintPath>
+      <Private>True</Private>
     </Reference>
-    <Reference Include="System.Runtime.CompilerServices.Unsafe, Version=6.0.0.0, Culture=neutral, PublicKeyToken=b03f5f7f11d50a3a, processorArchitecture=MSIL">
-      <HintPath>..\..\..\packages\System.Runtime.CompilerServices.Unsafe.6.0.0-preview.3.21201.4\lib\net45\System.Runtime.CompilerServices.Unsafe.dll</HintPath>
+    <Reference Include="System.Threading.Tasks.Extensions, Version=4.2.4.0, Culture=neutral, PublicKeyToken=cc7b13ffcd2ddd51">
+      <HintPath>..\..\..\packages\System.Threading.Tasks.Extensions.4.6.3\lib\net462\System.Threading.Tasks.Extensions.dll</HintPath>
+      <Private>True</Private>
     </Reference>
     <Reference Include="System.Transactions" />
     <Reference Include="System.Xml" />
@@ -375,6 +412,8 @@
     </PropertyGroup>
     <Error Condition="!Exists('..\..\..\packages\EntityFramework.6.4.4\build\EntityFramework.props')" Text="$([System.String]::Format('$(ErrorText)', '..\..\..\packages\EntityFramework.6.4.4\build\EntityFramework.props'))" />
     <Error Condition="!Exists('..\..\..\packages\EntityFramework.6.4.4\build\EntityFramework.targets')" Text="$([System.String]::Format('$(ErrorText)', '..\..\..\packages\EntityFramework.6.4.4\build\EntityFramework.targets'))" />
+    <Error Condition="!Exists('..\..\..\packages\System.ValueTuple.4.6.2\build\net471\System.ValueTuple.targets')" Text="$([System.String]::Format('$(ErrorText)', '..\..\..\packages\System.ValueTuple.4.6.2\build\net471\System.ValueTuple.targets'))" />
   </Target>
   <Import Project="..\..\..\packages\EntityFramework.6.4.4\build\EntityFramework.targets" Condition="Exists('..\..\..\packages\EntityFramework.6.4.4\build\EntityFramework.targets')" />
+  <Import Project="..\..\..\packages\System.ValueTuple.4.6.2\build\net471\System.ValueTuple.targets" Condition="Exists('..\..\..\packages\System.ValueTuple.4.6.2\build\net471\System.ValueTuple.targets')" />
 </Project>
\ No newline at end of file
diff --git a/src/GCModeller/data/KEGG/packages.config b/src/GCModeller/data/KEGG/packages.config
index cdead87ca69..30b314f135b 100644
--- a/src/GCModeller/data/KEGG/packages.config
+++ b/src/GCModeller/data/KEGG/packages.config
@@ -1,16 +1,25 @@
 <?xml version="1.0" encoding="utf-8"?>
 <packages>
   <package id="BouncyCastle" version="1.8.9" targetFramework="net48" />
+  <package id="BouncyCastle.Cryptography" version="2.7.0" targetFramework="net48" />
   <package id="EntityFramework" version="6.4.4" targetFramework="net48" />
   <package id="Google.Protobuf" version="3.17.0" targetFramework="net48" />
   <package id="K4os.Compression.LZ4" version="1.2.10-beta" targetFramework="net48" />
   <package id="K4os.Compression.LZ4.Streams" version="1.2.10-beta" targetFramework="net48" />
   <package id="K4os.Hash.xxHash" version="1.0.6" targetFramework="net48" />
+  <package id="Microsoft.Bcl.AsyncInterfaces" version="10.0.11" targetFramework="net48" />
+  <package id="Microsoft.Bcl.Cryptography" version="10.0.11" targetFramework="net48" />
+  <package id="Microsoft.Extensions.DependencyInjection.Abstractions" version="10.0.11" targetFramework="net48" />
+  <package id="Microsoft.Extensions.Logging.Abstractions" version="10.0.11" targetFramework="net48" />
   <package id="MySql.Data" version="8.0.25" targetFramework="net48" />
   <package id="MySql.Data.Entities" version="6.8.3.0" targetFramework="net48" />
-  <package id="SSH.NET" version="2020.0.2" targetFramework="net48" />
-  <package id="System.Buffers" version="4.5.1" targetFramework="net48" />
-  <package id="System.Memory" version="4.5.4" targetFramework="net48" />
-  <package id="System.Numerics.Vectors" version="4.5.0" targetFramework="net48" />
-  <package id="System.Runtime.CompilerServices.Unsafe" version="6.0.0-preview.3.21201.4" targetFramework="net48" />
+  <package id="SSH.NET" version="2026.0.0" targetFramework="net48" />
+  <package id="System.Buffers" version="4.6.1" targetFramework="net48" />
+  <package id="System.Diagnostics.DiagnosticSource" version="10.0.11" targetFramework="net48" />
+  <package id="System.Formats.Asn1" version="10.0.11" targetFramework="net48" />
+  <package id="System.Memory" version="4.6.3" targetFramework="net48" />
+  <package id="System.Numerics.Vectors" version="4.6.1" targetFramework="net48" />
+  <package id="System.Runtime.CompilerServices.Unsafe" version="6.1.2" targetFramework="net48" />
+  <package id="System.Threading.Tasks.Extensions" version="4.6.3" targetFramework="net48" />
+  <package id="System.ValueTuple" version="4.6.2" targetFramework="net48" />
 </packages>
\ No newline at end of file