diff --git a/projects/rocthrust/CHANGELOG.md b/projects/rocthrust/CHANGELOG.md
index ec4eeaeff72..e69d45b151c 100644
--- a/projects/rocthrust/CHANGELOG.md
+++ b/projects/rocthrust/CHANGELOG.md
@@ -8,6 +8,7 @@ Documentation for rocThrust available at
 ### Added
 
 * Added `thrust::unique_ptr` - a smart pointer for managing device memory with automatic cleanup.
+* Added a new cmake option, `BUILD_OFFLOAD_COMPRESS`. When rocThrust is build with this option enabled, the `--offload-compress` switch is passed to the compiler. This causes the compiler to compress the binary that it generates. Compression can be useful in cases where you are compiling for a large number of targets, since this often results in a large binary. Without compression, in some cases, the generated binary may become so large symbols are placed out of range, resulting in linking errors. The new `BUILD_OFFLOAD_COMPRESS` option is set to `ON` by default.
 
 ## rocThrust 4.1.0 for ROCm 7.1
 
diff --git a/projects/rocthrust/CMakeLists.txt b/projects/rocthrust/CMakeLists.txt
index 3ff52a91b32..4df30f528eb 100644
--- a/projects/rocthrust/CMakeLists.txt
+++ b/projects/rocthrust/CMakeLists.txt
@@ -59,6 +59,7 @@ option(BUILD_HIPSTDPAR_TEST_WITH_TBB "Build hipstdpar tests with TBB" OFF)
 option(BUILD_EXAMPLE "Build example" OFF)
 option(BUILD_BENCHMARK "Build benchmark" OFF)
 option(BUILD_ADDRESS_SANITIZER "Build with address sanitizer enabled" OFF)
+option(BUILD_OFFLOAD_COMPRESS "Build rocThrust with offload compression" ON)
 cmake_dependent_option(ENABLE_UPSTREAM_TESTS "Enable upstream (thrust) tests" ON BUILD_TEST OFF)
 cmake_dependent_option(USE_SYSTEM_LIB "Use existing system ROCm library installation when building tests" OFF BUILD_TEST OFF)
 option(EXTERNAL_DEPS_FORCE_DOWNLOAD "Force download of non-ROCm dependencies (eg. Google Test, Google Benchmark)" OFF)
@@ -66,6 +67,17 @@ option(EXTERNAL_DEPS_FORCE_DOWNLOAD "Force download of non-ROCm dependencies (eg
 check_language(HIP)
 cmake_dependent_option(USE_HIPCXX "Use CMake HIP language support" OFF CMAKE_HIP_COMPILER OFF)
 
+include(CheckCXXCompilerFlag)
+
+if(BUILD_OFFLOAD_COMPRESS)
+  check_cxx_compiler_flag("--offload-compress -x hip" CXX_COMPILER_SUPPORTS_OFFLOAD_COMPRESS)
+  if(CXX_COMPILER_SUPPORTS_OFFLOAD_COMPRESS)
+    set(CMAKE_CXX_FLAGS "${CMAKE_CXX_FLAGS} --offload-compress")
+  else()
+    message(STATUS "Warning: BUILD_OFFLOAD_COMPRESS=ON but flag not supported by compiler. Ignoring option.")
+  endif()
+endif()
+
 # Allow the user to optionally select offset type dispatch to fixed 32 or 64 bit types
 set(THRUST_DISPATCH_TYPE "Dynamic" CACHE STRING "Select Thrust offset type dispatch." FORCE)
 set_property(CACHE THRUST_DISPATCH_TYPE PROPERTY STRINGS "Dynamic" "Force32bit" "Force64bit")
@@ -127,6 +139,13 @@ else()
   endif()
 endif()
 
+# Compressed offload binaries are currently not working with the SPIR-V target
+if("amdgcnspirv" IN_LIST GPU_TARGETS)
+  if(BUILD_OFFLOAD_COMPRESS)
+    message(FATAL_ERROR "Cannot combine SPIR-V and BUILD_OFFLOAD_COMPRESS")
+  endif()
+endif()
+
 # Set up options for obtaining dependencies rocPRIM and rocRAND.
 # PACKAGE: Search for an install package that contains the dependency.
 # MONOREPO: Assume this is a monorepo checkout and search for the dependency in the directory at ../../projects/.
diff --git a/projects/rocthrust/cmake/Summary.cmake b/projects/rocthrust/cmake/Summary.cmake
index 9839ed543f3..c1abdaabb18 100644
--- a/projects/rocthrust/cmake/Summary.cmake
+++ b/projects/rocthrust/cmake/Summary.cmake
@@ -99,6 +99,7 @@ endif()
     message(STATUS "  BUILD_HIPSTDPAR_TEST_WITH_TBB   : ${BUILD_HIPSTDPAR_TEST_WITH_TBB}")
     message(STATUS "  BUILD_EXAMPLE                   : ${BUILD_EXAMPLE}")
     message(STATUS "  BUILD_BENCHMARK                 : ${BUILD_BENCHMARK}")
+    message(STATUS "  BUILD_OFFLOAD_COMPRESS          : ${BUILD_OFFLOAD_COMPRESS}")    
 if(BUILD_BENCHMARK)
     message(STATUS "  ROCRAND_FETCH_METHOD            : ${ROCRAND_FETCH_METHOD}")
 endif()
diff --git a/projects/rocthrust/rmake.py b/projects/rocthrust/rmake.py
index b2dec125510..02b8629dfec 100644
--- a/projects/rocthrust/rmake.py
+++ b/projects/rocthrust/rmake.py
@@ -42,6 +42,7 @@ def parse_args():
                         help='Set GPU architectures, e.g. all, gfx000, gfx803, gfx906:xnack-;gfx1030 (optional, default: all)')
     parser.add_argument('-v', '--verbose', required=False, default=False, action='store_true',
                         help='Verbose build (default: False)')
+    parser.add_argument('--no-offload-compress', required=False, default=False, action='store_true', help='Do not apply offload compression (defult: False)')                        
     return parser.parse_args()
 
 def os_detect():
@@ -159,6 +160,9 @@ def config_cmd():
     if args.build_clients:
         cmake_options.append( f"-DBUILD_TEST=ON -DBUILD_BENCHMARK=ON -DBUILD_DIR={build_dir}" )
 
+    if args.no_offload_compress:
+        cmake_options.append( f"-DBUILD_OFFLOAD_COMPRESS=OFF" )
+        
     cmake_options.append( f"-DAMDGPU_TARGETS={args.gpu_architecture}" )
 
     if args.cmake_dargs: