diff --git a/.github/workflows/therock-multi-arch-ci-asan-nightly.yml b/.github/workflows/therock-multi-arch-ci-asan-nightly.yml
index dcba50b4b30f..945c3507b112 100644
--- a/.github/workflows/therock-multi-arch-ci-asan-nightly.yml
+++ b/.github/workflows/therock-multi-arch-ci-asan-nightly.yml
@@ -32,6 +32,10 @@ jobs:
     with:
       build_variant: "asan"
       linux_amdgpu_families: "gfx94X,gfx950,gfx125X"
+      # Python/PyTorch/JAX builds are not supported with ASAN yet
+      build_python_packages: false
+      build_pytorch: false
+      build_jax: false
       repository: ROCm/TheRock
       ref: 3c4ec014374d4d32243334ef229093fe7b38c5b2 # 2026-08-31
       external_repo: '{"repository":"${{ github.repository }}","ref":"${{ github.sha }}"}'