diff --git a/build_tools/github_actions/configure_asan_env.py b/build_tools/github_actions/configure_asan_env.py
index bc024fed32d..765704e99f4 100644
--- a/build_tools/github_actions/configure_asan_env.py
+++ b/build_tools/github_actions/configure_asan_env.py
@@ -114,9 +114,28 @@ def _resolve_symbolizer(artifacts_dir: Path) -> tuple[Optional[Path], Optional[s
     return symbolizer.resolve(), None
 
 
-def _resolve_library_path(artifacts_dir: Path) -> str:
+def get_asan_runtime_path(artifacts_dir: Path) -> Path:
+    """Returns the configured runtime, or discovers it for standalone launchers."""
+    configured = os.environ.get("ASAN_RUNTIME_PATH")
+    if configured:
+        runtime = Path(configured)
+        if not runtime.is_file():
+            raise FileNotFoundError(f"ASAN_RUNTIME_PATH does not exist: {runtime}")
+        return runtime.resolve()
+
+    runtime, warning = _resolve_asan_runtime(artifacts_dir)
+    if runtime is None:
+        raise FileNotFoundError(warning)
+    return runtime
+
+
+def _resolve_library_path(artifacts_dir: Path, runtime: Path | None = None) -> str:
     lib_dir = (artifacts_dir / "lib").resolve()
     parts = [str(lib_dir), str(lib_dir / "rocm_sysdeps" / "lib")]
+    # -shared-libsan binaries and Python extensions need the clang resource
+    # directory as well as ROCm/lib, even when they do not preload ASan.
+    if runtime:
+        parts.append(str(runtime.parent))
     existing = os.environ.get("LD_LIBRARY_PATH")
     if existing:
         parts.append(existing)
@@ -140,7 +159,7 @@ def resolve_asan_env(artifacts_dir: Path) -> tuple[dict[str, str], list[str]]:
     if warning:
         warnings.append(warning)
 
-    env["LD_LIBRARY_PATH"] = _resolve_library_path(artifacts_dir)
+    env["LD_LIBRARY_PATH"] = _resolve_library_path(artifacts_dir, runtime)
 
     return env, warnings
 
diff --git a/build_tools/github_actions/test_executable_scripts/test_hiptests.py b/build_tools/github_actions/test_executable_scripts/test_hiptests.py
index 1f5d91faa53..6d3897b6b07 100644
--- a/build_tools/github_actions/test_executable_scripts/test_hiptests.py
+++ b/build_tools/github_actions/test_executable_scripts/test_hiptests.py
@@ -27,6 +27,7 @@
 # Importing is_asan from amdgpu_family_matrix.py
 sys.path.append(str(THEROCK_DIR / "build_tools" / "github_actions"))
 from amdgpu_family_matrix import is_asan
+from configure_asan_env import get_asan_runtime_path
 
 env = os.environ.copy()
 
@@ -107,17 +108,7 @@
 
 
 def get_asan_lib_path():
-    arch = platform.machine()
-    CLANG_PATH = str(Path(THEROCK_BIN_DIR).parent / "lib" / "llvm" / "bin" / "clang++")
-    cmd = [f"{CLANG_PATH}", f"--print-file-name=libclang_rt.asan-{arch}.so"]
-    logging.info(f"++ Exec [{CLANG_PATH}]$ {shlex.join(cmd)}")
-    result = subprocess.run(
-        cmd,
-        check=True,
-        text=True,
-        capture_output=True,
-    )
-    return result.stdout.strip()
+    return str(get_asan_runtime_path(THEROCK_BIN_DIR.resolve().parent))
 
 
 def copy_dlls_exe_path():
diff --git a/build_tools/github_actions/test_executable_scripts/test_rocprofiler_sdk.py b/build_tools/github_actions/test_executable_scripts/test_rocprofiler_sdk.py
index bb94de8d0ff..348acc74a0a 100644
--- a/build_tools/github_actions/test_executable_scripts/test_rocprofiler_sdk.py
+++ b/build_tools/github_actions/test_executable_scripts/test_rocprofiler_sdk.py
@@ -25,6 +25,7 @@
 THEROCK_DIR = SCRIPT_DIR.parent.parent.parent
 sys.path.append(str(THEROCK_DIR / "build_tools" / "github_actions"))
 from amdgpu_family_matrix import is_asan
+from configure_asan_env import get_asan_runtime_path
 
 # Base Paths
 THEROCK_BIN_DIR = os.getenv("THEROCK_BIN_DIR")
@@ -97,29 +98,7 @@
 
 def get_asan_runtime_library():
     """Return the clang AddressSanitizer runtime path."""
-    machine = platform.machine()
-    if machine in ("x86_64", "AMD64"):
-        arch = "x86_64"
-    elif machine == "aarch64":
-        arch = "aarch64"
-    else:
-        raise RuntimeError(f"Unsupported ASan runtime architecture: {machine}")
-
-    asan_lib = f"libclang_rt.asan-{arch}.so"
-    result = subprocess.run(
-        [str(THEROCK_CLANG_PLUS_PATH), f"-print-file-name={asan_lib}"],
-        check=True,
-        capture_output=True,
-        text=True,
-        env=environ_vars,
-    )
-    resolved = result.stdout.strip()
-    if not resolved or resolved == asan_lib or not Path(resolved).is_file():
-        raise FileNotFoundError(
-            f"Could not locate ASan runtime '{asan_lib}' via {THEROCK_CLANG_PLUS_PATH} "
-            f"(got: '{resolved}')"
-        )
-    return str(Path(resolved).resolve())
+    return str(get_asan_runtime_path(THEROCK_PATH))
 
 
 def setup_env():
@@ -134,7 +113,7 @@ def setup_env():
 
     if is_asan():
         # Installed test binaries are built with -shared-libsan, so the clang
-        # resource dir holding libclang_rt.asan-<arch>.so must be on the loader
+        # resource dir holding the ASan runtime must be on the loader
         # search path. Match rocprofiler-sdk sanitizer defaults for launchers.
         ld_lib_paths.append(str(Path(get_asan_runtime_library()).parent))
 
diff --git a/build_tools/github_actions/tests/configure_asan_env_test.py b/build_tools/github_actions/tests/configure_asan_env_test.py
index 47493d7d994..796dcf429b6 100644
--- a/build_tools/github_actions/tests/configure_asan_env_test.py
+++ b/build_tools/github_actions/tests/configure_asan_env_test.py
@@ -56,6 +56,10 @@ def test_resolves_runtime_and_symbolizer(self):
             self.assertEqual(warnings, [])
             self.assertTrue(env["ASAN_RUNTIME_PATH"].endswith("asan.so"))
             self.assertTrue(env["ASAN_SYMBOLIZER_PATH"].endswith("llvm-symbolizer"))
+            self.assertIn(
+                str(Path(env["ASAN_RUNTIME_PATH"]).parent),
+                env["LD_LIBRARY_PATH"].split(":"),
+            )
 
     def test_static_values_are_always_exported(self):
         with tempfile.TemporaryDirectory() as tmp:
diff --git a/build_tools/github_actions/tests/rocprofiler_sdk_dashboard_test.py b/build_tools/github_actions/tests/rocprofiler_sdk_dashboard_test.py
index 6aa6fe64786..aa101f0665a 100644
--- a/build_tools/github_actions/tests/rocprofiler_sdk_dashboard_test.py
+++ b/build_tools/github_actions/tests/rocprofiler_sdk_dashboard_test.py
@@ -88,13 +88,18 @@ def test_asan_dashboard_preserves_mainline_configuration_and_exclusions(self):
             patch.object(test_rocprofiler_sdk, "is_asan", return_value=True),
             patch.object(
                 test_rocprofiler_sdk,
-                "get_asan_runtime_library",
-                return_value="/tmp/libclang_rt.asan-x86_64.so",
+                "get_asan_runtime_path",
+                return_value=Path("/tmp/libclang_rt.asan.so"),
             ),
         ):
             dashboard = self._generate()
+            command = test_rocprofiler_sdk.get_cmake_config_cmd()
 
         self.assertIn("-DROCPROFILER_MEMCHECK=AddressSanitizer", dashboard)
+        self.assertIn(
+            f"-DROCPROFILER_MEMCHECK_PRELOAD_ENV=LD_PRELOAD={Path('/tmp/libclang_rt.asan.so')}",
+            command,
+        )
         self.assertIn(
             'EXCLUDE "rocprofiler_sdk.unit.spm_core.check_packet_generation|',
             dashboard,