diff --git a/pkgs/development/interpreters/python/cpython/default.nix b/pkgs/development/interpreters/python/cpython/default.nix
index 13ede05bf2b72..b0fd13b6a928c 100644
--- a/pkgs/development/interpreters/python/cpython/default.nix
+++ b/pkgs/development/interpreters/python/cpython/default.nix
@@ -152,8 +152,6 @@ let
 
   passthru =
     let
-      # When we override the interpreter we also need to override the spliced versions of the interpreter
-      inputs' = lib.filterAttrs (n: v: n != "passthruFun" && !lib.isDerivation v) inputs;
       # Memoization of the splices to avoid re-evaluating this function for all combinations of splices e.g.
       # python3.pythonOnBuildForHost.pythonOnBuildForTarget == python3.pythonOnBuildForTarget by consuming
       # __splices as an arg and using the cache if populated.
@@ -170,13 +168,9 @@ let
       override =
         attr:
         let
-          python = attr.override (
-            inputs'
-            // {
-              self = python;
-              __splices = splices;
-            }
-          );
+          python = attr.override {
+            self = python;
+          };
         in
         python;
     in
diff --git a/pkgs/development/python-modules/setuptools-rust/default.nix b/pkgs/development/python-modules/setuptools-rust/default.nix
index 79158cf1ea639..a13c0e7be526a 100644
--- a/pkgs/development/python-modules/setuptools-rust/default.nix
+++ b/pkgs/development/python-modules/setuptools-rust/default.nix
@@ -43,16 +43,11 @@ buildPythonPackage rec {
   # integrate the setup hook to set up the build environment for cross compilation
   # this hook is automatically propagated to consumers using setuptools-rust as build-system
   #
-  # No need for the setup hook when python.pythonOnTargetForTarget is empty,
-  # or when the host & target platforms are the same.
-  #
+  # Only include the setup hook if python.pythonOnTargetForTarget is not empty.
   # python.pythonOnTargetForTarget is not always available, for example in
   # pkgsLLVM.python3.pythonOnTargetForTarget. cross build with pkgsLLVM should not be affected.
   setupHook =
-    if
-      python.pythonOnTargetForTarget == { }
-      || (lib.systems.equals stdenv.hostPlatform stdenv.targetPlatform)
-    then
+    if python.pythonOnTargetForTarget == { } then
       null
     else
       replaceVars ./setuptools-rust-hook.sh {