diff --git a/pkgs/by-name/fr/fractal/package.nix b/pkgs/by-name/fr/fractal/package.nix
index 57e2d580238e1..66e3a059f61c8 100644
--- a/pkgs/by-name/fr/fractal/package.nix
+++ b/pkgs/by-name/fr/fractal/package.nix
@@ -29,6 +29,7 @@
   libseccomp,
   glycin-loaders,
   libwebp,
+  libglycin,
 }:
 
 stdenv.mkDerivation (finalAttrs: {
@@ -60,6 +61,14 @@ stdenv.mkDerivation (finalAttrs: {
       "target_dir / '${stdenv.hostPlatform.rust.cargoShortTarget}' / rust_target / meson.project_name()"
   '';
 
+  preConfigure = ''
+    # Dirty approach to add patches after cargoSetupPostUnpackHook
+    # We should eventually use a cargo vendor patch hook instead
+    pushd ../$(stripHash $cargoDeps)/glycin-3.*
+      patch -p3 < ${libglycin.passthru.glycin3PathsPatch}
+      patch -p3 < ${libglycin.passthru.glycin3OptionalUsrPatch}
+    popd
+  '';
   nativeBuildInputs = [
     glib
     grass-sass
@@ -102,7 +111,6 @@ stdenv.mkDerivation (finalAttrs: {
   preFixup = ''
     gappsWrapperArgs+=(
       --prefix XDG_DATA_DIRS : "${glycin-loaders}/share"
-      --prefix PATH : "${lib.makeBinPath [ bubblewrap ]}"
     )
   '';
 
diff --git a/pkgs/by-name/li/libglycin/glycin-3-optional-usr.patch b/pkgs/by-name/li/libglycin/glycin-3-optional-usr.patch
new file mode 100644
index 0000000000000..96a07d1627216
--- /dev/null
+++ b/pkgs/by-name/li/libglycin/glycin-3-optional-usr.patch
@@ -0,0 +1,13 @@
+diff --git a/vendor/glycin/src/sandbox.rs b/vendor/glycin/src/sandbox.rs
+index d840674..475d4be 100644
+--- a/vendor/glycin/src/sandbox.rs
++++ b/vendor/glycin/src/sandbox.rs
+@@ -292,7 +292,7 @@ impl Sandbox {
+             "--chdir",
+             "/",
+             // Make /usr available as read only
+-            "--ro-bind",
++            "--ro-bind-try",
+             "/usr",
+             "/usr",
+             // Make tmpfs dev available
diff --git a/pkgs/by-name/li/libglycin/package.nix b/pkgs/by-name/li/libglycin/package.nix
index 324c6ff988d2e..cc2db7bddc8b3 100644
--- a/pkgs/by-name/li/libglycin/package.nix
+++ b/pkgs/by-name/li/libglycin/package.nix
@@ -79,6 +79,7 @@ stdenv.mkDerivation (finalAttrs: {
 
   postPatch = ''
     patch -p2 < ${finalAttrs.passthru.glycin3PathsPatch}
+    patch -p2 < ${finalAttrs.passthru.glycin3OptionalUsrPatch}
 
     patchShebangs \
       build-aux/crates-version.py
@@ -120,6 +121,8 @@ stdenv.mkDerivation (finalAttrs: {
     glycin3PathsPatch = replaceVars ./fix-glycin-3-paths.patch {
       bwrap = "${bubblewrap}/bin/bwrap";
     };
+
+    glycin3OptionalUsrPatch = ./glycin-3-optional-usr.patch;
   };
 
   meta = {
diff --git a/pkgs/by-name/lo/loupe/package.nix b/pkgs/by-name/lo/loupe/package.nix
index 38a902de5a81f..85aab97d44743 100644
--- a/pkgs/by-name/lo/loupe/package.nix
+++ b/pkgs/by-name/lo/loupe/package.nix
@@ -69,6 +69,7 @@ stdenv.mkDerivation (finalAttrs: {
     # We should eventually use a cargo vendor patch hook instead
     pushd ../$(stripHash $cargoDeps)/glycin-3.*
       patch -p3 < ${libglycin.passthru.glycin3PathsPatch}
+      patch -p3 < ${libglycin.passthru.glycin3OptionalUsrPatch}
     popd
   '';
 
diff --git a/pkgs/by-name/sn/snapshot/package.nix b/pkgs/by-name/sn/snapshot/package.nix
index 8c8a480bfeb1c..f4e0e86222920 100644
--- a/pkgs/by-name/sn/snapshot/package.nix
+++ b/pkgs/by-name/sn/snapshot/package.nix
@@ -37,6 +37,8 @@ stdenv.mkDerivation (finalAttrs: {
   patches = [
     # Fix paths in glycin library
     libglycin.passthru.glycin3PathsPatch
+    # Make /usr optional in glycin library
+    libglycin.passthru.glycin3OptionalUsrPatch
   ];
 
   cargoVendorDir = "vendor";