diff --git a/pkgs/by-name/ni/nixos-rebuild-ng/src/nixos_rebuild/nix.py b/pkgs/by-name/ni/nixos-rebuild-ng/src/nixos_rebuild/nix.py
index dc95b914b360b..344350687774c 100644
--- a/pkgs/by-name/ni/nixos-rebuild-ng/src/nixos_rebuild/nix.py
+++ b/pkgs/by-name/ni/nixos-rebuild-ng/src/nixos_rebuild/nix.py
@@ -86,7 +86,18 @@ def build_flake(
         flake.to_attr(attr),
         *dict_to_flags(flake_build_flags),
     ]
-    r = run_wrapper(run_args, stdout=PIPE, stderr=PIPE if quiet else None)
+    r = run_wrapper(
+        run_args,
+        stdout=PIPE,
+        stderr=PIPE if quiet else None,
+        # Running build inside tmpdir thanks to this nasty bug from `nix`
+        # that happens when `nix build` is run from a symlink pointing to the
+        # nix store (e.g., /run/opengl-driver/lib)
+        # See:
+        # - https://github.com/NixOS/nix/issues/13367
+        # - https://github.com/NixOS/nixpkgs/issues/144811
+        cwd=tmpdir.TMPDIR_PATH,
+    )
     return Path(r.stdout.strip())
 
 
diff --git a/pkgs/by-name/ni/nixos-rebuild-ng/src/nixos_rebuild/process.py b/pkgs/by-name/ni/nixos-rebuild-ng/src/nixos_rebuild/process.py
index 462c4178e8f7a..43800e50ba091 100644
--- a/pkgs/by-name/ni/nixos-rebuild-ng/src/nixos_rebuild/process.py
+++ b/pkgs/by-name/ni/nixos-rebuild-ng/src/nixos_rebuild/process.py
@@ -7,6 +7,7 @@
 import subprocess
 from collections.abc import Sequence
 from dataclasses import dataclass
+from pathlib import Path
 from typing import Final, Self, TypedDict, Unpack
 
 from . import tmpdir
@@ -67,6 +68,7 @@ def _validate_opts(opts: list[str], ask_sudo_password: bool | None) -> None:
 # Not exhaustive, but we can always extend it later.
 class RunKwargs(TypedDict, total=False):
     capture_output: bool
+    cwd: str | Path | None
     stderr: int | None
     stdout: int | None
 
diff --git a/pkgs/by-name/ni/nixos-rebuild-ng/src/tests/test_main.py b/pkgs/by-name/ni/nixos-rebuild-ng/src/tests/test_main.py
index 22b7054000a89..914dac8211b7d 100644
--- a/pkgs/by-name/ni/nixos-rebuild-ng/src/tests/test_main.py
+++ b/pkgs/by-name/ni/nixos-rebuild-ng/src/tests/test_main.py
@@ -11,6 +11,7 @@
 from pytest import MonkeyPatch
 
 import nixos_rebuild as nr
+from nixos_rebuild import tmpdir
 
 from .helpers import get_qualified_name
 
@@ -409,6 +410,7 @@ def run_side_effect(args: list[str], **kwargs: Any) -> CompletedProcess[str]:
                 check=True,
                 stdout=PIPE,
                 stderr=None,
+                cwd=tmpdir.TMPDIR_PATH,
                 **DEFAULT_RUN_KWARGS,
             ),
             call(
@@ -477,6 +479,7 @@ def run_side_effect(args: list[str], **kwargs: Any) -> CompletedProcess[str]:
                 check=True,
                 stdout=PIPE,
                 stderr=None,
+                cwd=tmpdir.TMPDIR_PATH,
                 **DEFAULT_RUN_KWARGS,
             ),
             call(
@@ -768,6 +771,7 @@ def run_side_effect(args: list[str], **kwargs: Any) -> CompletedProcess[str]:
                 check=True,
                 stdout=PIPE,
                 stderr=None,
+                cwd=tmpdir.TMPDIR_PATH,
                 **DEFAULT_RUN_KWARGS,
             ),
             call(
@@ -1076,6 +1080,7 @@ def run_side_effect(args: list[str], **kwargs: Any) -> CompletedProcess[str]:
                 check=True,
                 stdout=PIPE,
                 stderr=None,
+                cwd=tmpdir.TMPDIR_PATH,
                 **DEFAULT_RUN_KWARGS,
             ),
             call(
diff --git a/pkgs/by-name/ni/nixos-rebuild-ng/src/tests/test_nix.py b/pkgs/by-name/ni/nixos-rebuild-ng/src/tests/test_nix.py
index 195f929aaf534..661a19e0b2bf0 100644
--- a/pkgs/by-name/ni/nixos-rebuild-ng/src/tests/test_nix.py
+++ b/pkgs/by-name/ni/nixos-rebuild-ng/src/tests/test_nix.py
@@ -79,6 +79,7 @@ def test_build_flake(mock_run: Mock, monkeypatch: MonkeyPatch, tmpdir: Path) ->
         ],
         stdout=PIPE,
         stderr=None,
+        cwd=ANY,
     )
 
     assert n.build_flake(
@@ -98,6 +99,7 @@ def test_build_flake(mock_run: Mock, monkeypatch: MonkeyPatch, tmpdir: Path) ->
         ],
         stdout=PIPE,
         stderr=PIPE,
+        cwd=ANY,
     )