diff --git a/pkgs/applications/networking/cluster/nixops/default.nix b/pkgs/applications/networking/cluster/nixops/default.nix
index d9d31d94ac96b..88c426565fc4e 100644
--- a/pkgs/applications/networking/cluster/nixops/default.nix
+++ b/pkgs/applications/networking/cluster/nixops/default.nix
@@ -19,13 +19,13 @@ let
     };
 
     plugins = ps: _super: with ps; rec {
-      nixops-aws = callPackage ./plugins/nixops-aws.nix { };
       nixops-digitalocean = callPackage ./plugins/nixops-digitalocean.nix { };
       nixops-encrypted-links = callPackage ./plugins/nixops-encrypted-links.nix { };
       nixops-hercules-ci = callPackage ./plugins/nixops-hercules-ci.nix { };
       nixops-vbox = callPackage ./plugins/nixops-vbox.nix { };
       nixos-modules-contrib = callPackage ./plugins/nixos-modules-contrib.nix { };
 
+      nixops-aws = throw "nixops-aws was broken and was removed from nixpkgs";
       nixops-gce = throw "nixops-gce was broken and was removed from nixpkgs";
       nixops-libvirtd = throw "nixops-libvirtd was broken and was removed from nixpkgs";
       nixops-hetzner = throw "nixops-hetzner was broken and was removed from nixpkgs";
@@ -42,7 +42,7 @@ let
     selectedPlugins = [];
 
     # selector is a function mapping pythonPackages to a list of plugins
-    # e.g. nixops_unstable.withPlugins (ps: with ps; [ nixops-aws ])
+    # e.g. nixops_unstable.withPlugins (ps: with ps; [ nixops-digitalocean ])
     withPlugins = selector:
       this.extend (this: _old: {
         selectedPlugins = selector this.availablePlugins;
@@ -109,8 +109,6 @@ in
 
   # Not recommended; too fragile.
   nixops_unstable_full = minimal.withPlugins (ps: [
-    # currently broken
-    # ps.nixops-aws
     ps.nixops-digitalocean
     ps.nixops-encrypted-links
     ps.nixops-hercules-ci
diff --git a/pkgs/applications/networking/cluster/nixops/plugins/nixops-aws.nix b/pkgs/applications/networking/cluster/nixops/plugins/nixops-aws.nix
deleted file mode 100644
index 895794d3e0f66..0000000000000
--- a/pkgs/applications/networking/cluster/nixops/plugins/nixops-aws.nix
+++ /dev/null
@@ -1,59 +0,0 @@
-{ lib
-, buildPythonPackage
-, fetchFromGitHub
-, unstableGitUpdater
-, poetry-core
-, boto
-, boto3
-, nixops
-, nixos-modules-contrib
-, typing-extensions
-}:
-
-buildPythonPackage {
-  pname = "nixops-aws";
-  version = "1.0.0-unstable-2024-02-29";
-  pyproject = true;
-
-  src = fetchFromGitHub {
-    owner = "NixOS";
-    repo = "nixops-aws";
-    rev = "d173b2f14ec767d782ceab45fb22b32fe3b5a1f7";
-    hash = "sha256-ocTtc7POt1bugb9Bki2ew2Eh5uc933GftNw1twoOJsc=";
-  };
-
-  postPatch = ''
-    substituteInPlace pyproject.toml \
-    --replace poetry.masonry.api poetry.core.masonry.api \
-    --replace "poetry>=" "poetry-core>="
-  '';
-
-  nativeBuildInputs = [
-    poetry-core
-  ];
-
-  buildInputs = [
-    nixops
-  ];
-
-  propagatedBuildInputs = [
-    boto
-    boto3
-    nixos-modules-contrib
-    typing-extensions
-  ];
-
-  pythonImportsCheck = [ "nixops_aws" ];
-
-  passthru.updateScript = unstableGitUpdater {
-    tagPrefix = "v";
-  };
-
-  meta = with lib; {
-    description = "AWS plugin for NixOps";
-    homepage = "https://github.com/NixOS/nixops-aws";
-    license = licenses.lgpl3Only;
-    broken = true; # fails with `nose-1.3.7 not supported for interpreter python3.12`
-    maintainers = nixops.meta.maintainers;
-  };
-}
diff --git a/pkgs/applications/science/misc/toil/default.nix b/pkgs/applications/science/misc/toil/default.nix
deleted file mode 100644
index 9142676fff48d..0000000000000
--- a/pkgs/applications/science/misc/toil/default.nix
+++ /dev/null
@@ -1,90 +0,0 @@
-{ lib
-, fetchFromGitHub
-, python3
-, rsync
-}:
-
-python3.pkgs.buildPythonApplication rec {
-  pname = "toil";
-  version = "5.12.0";
-  format = "setuptools";
-
-  src = fetchFromGitHub {
-    owner = "DataBiosphere";
-    repo = pname;
-    rev = "refs/tags/releases/${version}";
-    hash = "sha256-cTpbQo9tPZifUO59vbnIa3XUinFJ2/5Slfe4yszglFM=";
-  };
-
-  propagatedBuildInputs = with python3.pkgs; [
-    addict
-    dill
-    docker
-    enlighten
-    psutil
-    py-tes
-    pypubsub
-    python-dateutil
-    pytz
-    pyyaml
-    requests
-    typing-extensions
-  ];
-
-  nativeCheckInputs = [
-    rsync
-  ] ++ (with python3.pkgs; [
-    boto
-    botocore
-    flask
-    pytestCheckHook
-    stubserver
-  ]);
-
-  pytestFlagsArray = [
-    "src/toil/test"
-  ];
-
-  pythonImportsCheck = [
-    "toil"
-  ];
-
-  disabledTestPaths = [
-    # Tests are reaching their timeout
-    "src/toil/test/docs/scriptsTest.py"
-    "src/toil/test/jobStores/jobStoreTest.py"
-    "src/toil/test/provisioners/aws/awsProvisionerTest.py"
-    "src/toil/test/src"
-    "src/toil/test/wdl"
-    "src/toil/test/utils/utilsTest.py"
-    "src/toil/test/cwl/cwlTest.py"
-    "src/toil/test/lib/test_ec2.py"
-    "src/toil/test/lib/aws/test_iam.py"
-    "src/toil/test/lib/aws/test_s3.py"
-  ];
-
-  disabledTests = [
-    # Tests fail starting with 5.7.1
-    "testServices"
-    "testConcurrencyWithDisk"
-    "testJobConcurrency"
-    "testNestedResourcesDoNotBlock"
-    "test_omp_threads"
-    "testFileSingle"
-    "testFileSingle10000"
-    "testFileSingleCheckpoints"
-    "testFileSingleNonCaching"
-    "testFetchJobStoreFiles"
-    "testFetchJobStoreFilesWSymlinks"
-    "testJobStoreContents"
-    "test_cwl_on_arm"
-    "test_cwl_toil_kill"
-  ];
-
-  meta = with lib; {
-    description = "Workflow engine written in pure Python";
-    homepage = "https://toil.ucsc-cgl.org/";
-    license = with licenses; [ asl20 ];
-    maintainers = with maintainers; [ veprbl ];
-  };
-}
diff --git a/pkgs/development/python-modules/boto/0005-Don-t-mock-list-subclass.patch b/pkgs/development/python-modules/boto/0005-Don-t-mock-list-subclass.patch
deleted file mode 100644
index 4add58640d7ae..0000000000000
--- a/pkgs/development/python-modules/boto/0005-Don-t-mock-list-subclass.patch
+++ /dev/null
@@ -1,21 +0,0 @@
-From: Jochen Sprickerhof <jspricke@debian.org>
-Date: Thu, 15 Dec 2022 07:44:54 +0100
-Subject: Don't mock list subclass
-
----
- tests/unit/ec2/test_volume.py | 2 +-
- 1 file changed, 1 insertion(+), 1 deletion(-)
-
-diff --git a/tests/unit/ec2/test_volume.py b/tests/unit/ec2/test_volume.py
-index 81d7f55..d4d8e4f 100644
---- a/tests/unit/ec2/test_volume.py
-+++ b/tests/unit/ec2/test_volume.py
-@@ -55,7 +55,7 @@ class VolumeTests(unittest.TestCase):
-     @mock.patch("boto.resultset.ResultSet")
-     def test_startElement_with_name_tagSet_calls_ResultSet(self, ResultSet, startElement):
-         startElement.return_value = None
--        result_set = mock.Mock(ResultSet([("item", Tag)]))
-+        result_set = ResultSet([("item", Tag)])
-         volume = Volume()
-         volume.tags = result_set
-         retval = volume.startElement("tagSet", None, None)
diff --git a/pkgs/development/python-modules/boto/bug-953970_python3.8-compat.patch b/pkgs/development/python-modules/boto/bug-953970_python3.8-compat.patch
deleted file mode 100644
index ac56210423753..0000000000000
--- a/pkgs/development/python-modules/boto/bug-953970_python3.8-compat.patch
+++ /dev/null
@@ -1,53 +0,0 @@
-Index: python-boto/tests/unit/utils/test_utils.py
-===================================================================
---- python-boto.orig/tests/unit/utils/test_utils.py
-+++ python-boto/tests/unit/utils/test_utils.py
-@@ -85,7 +85,7 @@ class TestPassword(unittest.TestCase):
-         def hmac_hashfunc(cls, msg):
-             if not isinstance(msg, bytes):
-                 msg = msg.encode('utf-8')
--            return hmac.new(b'mysecretkey', msg)
-+            return hmac.new(b'mysecretkey', msg, digestmod='sha256')
-
-         class HMACPassword(Password):
-             hashfunc = hmac_hashfunc
-@@ -95,15 +95,15 @@ class TestPassword(unittest.TestCase):
-         password.set('foo')
-
-         self.assertEquals(str(password),
--                          hmac.new(b'mysecretkey', b'foo').hexdigest())
-+                          hmac.new(b'mysecretkey', b'foo', digestmod='sha256').hexdigest())
-
-     def test_constructor(self):
--        hmac_hashfunc = lambda msg: hmac.new(b'mysecretkey', msg)
-+        hmac_hashfunc = lambda msg: hmac.new(b'mysecretkey', msg, digestmod='sha256')
-
-         password = Password(hashfunc=hmac_hashfunc)
-         password.set('foo')
-         self.assertEquals(password.str,
--                          hmac.new(b'mysecretkey', b'foo').hexdigest())
-+                          hmac.new(b'mysecretkey', b'foo', digestmod='sha256').hexdigest())
-
-
- class TestPythonizeName(unittest.TestCase):
-Index: python-boto/boto/ecs/item.py
-===================================================================
---- python-boto.orig/boto/ecs/item.py
-+++ python-boto/boto/ecs/item.py
-@@ -22,6 +22,7 @@
-
- import xml.sax
- import cgi
-+from html import escape
- from boto.compat import six, StringIO
-
- class ResponseGroup(xml.sax.ContentHandler):
-@@ -67,7 +68,7 @@ class ResponseGroup(xml.sax.ContentHandl
-         return None
-
-     def endElement(self, name, value, connection):
--        self._xml.write("%s</%s>" % (cgi.escape(value).replace("&amp;amp;", "&amp;"), name))
-+        self._xml.write("%s</%s>" % (escape(value).replace("&amp;amp;", "&amp;"), name))
-         if len(self._nodepath) == 0:
-             return
-         obj = None
diff --git a/pkgs/development/python-modules/boto/default.nix b/pkgs/development/python-modules/boto/default.nix
deleted file mode 100644
index 3549c6986cf13..0000000000000
--- a/pkgs/development/python-modules/boto/default.nix
+++ /dev/null
@@ -1,66 +0,0 @@
-{
-  lib,
-  buildPythonPackage,
-  fetchPypi,
-  python,
-  nose,
-  mock,
-  requests,
-  httpretty,
-}:
-
-buildPythonPackage rec {
-  pname = "boto";
-  version = "2.49.0";
-  format = "setuptools";
-
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "ea0d3b40a2d852767be77ca343b58a9e3a4b00d9db440efb8da74b4e58025e5a";
-  };
-
-  patches = [
-    # fixes hmac tests
-    # https://sources.debian.org/src/python-boto/2.49.0-4/debian/patches/bug-953970_python3.8-compat.patch/
-    ./bug-953970_python3.8-compat.patch
-    # fixes test_startElement_with_name_tagSet_calls_ResultSet
-    # https://sources.debian.org/src/python-boto/2.49.0-4.1/debian/patches/0005-Don-t-mock-list-subclass.patch/
-    ./0005-Don-t-mock-list-subclass.patch
-  ];
-
-  # boto is deprecated by upstream as of 2021-05-27 (https://github.com/boto/boto/commit/4980ac58764c3d401cb0b9552101f9c61c18f445)
-  # this patch is a bit simpler than https://github.com/boto/boto/pull/3898
-  # as we don't have to take care of pythonOlder "3.3".
-  postPatch = ''
-    substituteInPlace boto/dynamodb/types.py --replace 'from collections import Mapping' 'from collections.abc import Mapping'
-    substituteInPlace boto/mws/connection.py --replace 'import collections' 'import collections.abc as collections'
-  '';
-
-  checkPhase = ''
-    ${python.interpreter} tests/test.py default
-  '';
-
-  nativeCheckInputs = [
-    nose
-    mock
-  ];
-  propagatedBuildInputs = [
-    requests
-    httpretty
-  ];
-
-  meta = with lib; {
-    homepage = "https://github.com/boto/boto";
-    license = licenses.mit;
-    description = "Python interface to Amazon Web Services";
-    longDescription = ''
-      The boto module is an integrated interface to current and
-      future infrastructural services offered by Amazon Web
-      Services.  This includes S3, SQS, EC2, among others.
-    '';
-    maintainers = [ ];
-    # Unmaintained since 2020, archived in the beginning of May 2024 and broken
-    # https://github.com/boto/boto/issues/3951
-    broken = true;
-  };
-}
diff --git a/pkgs/development/python-modules/flask-admin/default.nix b/pkgs/development/python-modules/flask-admin/default.nix
index 38ab5efc74703..e9da4f44b6659 100644
--- a/pkgs/development/python-modules/flask-admin/default.nix
+++ b/pkgs/development/python-modules/flask-admin/default.nix
@@ -1,7 +1,6 @@
 {
   lib,
   azure-storage-blob,
-  boto,
   buildPythonPackage,
   fetchpatch,
   fetchFromGitHub,
@@ -53,7 +52,6 @@ buildPythonPackage rec {
   ];
 
   optional-dependencies = {
-    aws = [ boto ];
     azure = [ azure-storage-blob ];
   };
 
diff --git a/pkgs/development/python-modules/gcs-oauth2-boto-plugin/default.nix b/pkgs/development/python-modules/gcs-oauth2-boto-plugin/default.nix
deleted file mode 100644
index 0cb900cffb8d9..0000000000000
--- a/pkgs/development/python-modules/gcs-oauth2-boto-plugin/default.nix
+++ /dev/null
@@ -1,61 +0,0 @@
-{
-  lib,
-  boto,
-  buildPythonPackage,
-  fetchFromGitHub,
-  freezegun,
-  google-reauth,
-  httplib2,
-  oauth2client,
-  pyopenssl,
-  pytestCheckHook,
-  pythonOlder,
-  retry-decorator,
-  rsa,
-  six,
-}:
-
-buildPythonPackage rec {
-  pname = "gcs-oauth2-boto-plugin";
-  version = "3.0";
-  format = "setuptools";
-
-  disabled = pythonOlder "3.7";
-
-  src = fetchFromGitHub {
-    owner = "GoogleCloudPlatform";
-    repo = pname;
-    rev = "refs/tags/v${version}";
-    hash = "sha256-slTxh2j9VhLiSyiTmJIFFakzpzH/+mgilDRxx0VqqKQ=";
-  };
-
-  postPatch = ''
-    substituteInPlace setup.py \
-      --replace "rsa==4.7.2" "rsa" \
-      --replace "version='2.7'" "version='${version}'"
-  '';
-
-  propagatedBuildInputs = [
-    boto
-    freezegun
-    google-reauth
-    httplib2
-    oauth2client
-    pyopenssl
-    retry-decorator
-    rsa
-    six
-  ];
-
-  nativeCheckInputs = [ pytestCheckHook ];
-
-  pythonImportsCheck = [ "gcs_oauth2_boto_plugin" ];
-
-  meta = with lib; {
-    description = "Auth plugin allowing use the use of OAuth 2.0 credentials for Google Cloud Storage";
-    homepage = "https://github.com/GoogleCloudPlatform/gcs-oauth2-boto-plugin";
-    changelog = "https://github.com/GoogleCloudPlatform/gcs-oauth2-boto-plugin/releases/tag/v${version}";
-    license = with licenses; [ asl20 ];
-    maintainers = with maintainers; [ fab ];
-  };
-}
diff --git a/pkgs/development/python-modules/qds-sdk/default.nix b/pkgs/development/python-modules/qds-sdk/default.nix
deleted file mode 100644
index 34876b7aaa856..0000000000000
--- a/pkgs/development/python-modules/qds-sdk/default.nix
+++ /dev/null
@@ -1,51 +0,0 @@
-{
-  lib,
-  buildPythonPackage,
-  fetchFromGitHub,
-  setuptools,
-  boto,
-  inflection,
-  requests,
-  six,
-  urllib3,
-  mock,
-  pytestCheckHook,
-}:
-
-buildPythonPackage rec {
-  pname = "qds-sdk";
-  version = "1.16.1";
-  pyproject = true;
-
-  src = fetchFromGitHub {
-    owner = "qubole";
-    repo = "qds-sdk-py";
-    rev = "refs/tags/V${version}";
-    hash = "sha256-8aPIE2E3Fy2EiBM2FPRyjnJolIBdOzafI3Fvlod5hxU=";
-  };
-
-  nativeBuildInputs = [ setuptools ];
-
-  propagatedBuildInputs = [
-    boto
-    inflection
-    requests
-    six
-    urllib3
-  ];
-
-  nativeCheckInputs = [
-    pytestCheckHook
-    mock
-  ];
-
-  pythonImportsCheck = [ "qds_sdk" ];
-
-  meta = with lib; {
-    description = "Python module that provides the tools you need to authenticate with, and use the Qubole Data Service API";
-    homepage = "https://github.com/qubole/qds-sdk-py";
-    license = licenses.asl20;
-    maintainers = with maintainers; [ shahrukh330 ];
-    mainProgram = "qds.py";
-  };
-}
diff --git a/pkgs/tools/backup/wal-e/default.nix b/pkgs/tools/backup/wal-e/default.nix
deleted file mode 100644
index f1dda5da28093..0000000000000
--- a/pkgs/tools/backup/wal-e/default.nix
+++ /dev/null
@@ -1,37 +0,0 @@
-{ lib, fetchFromGitHub, python3Packages, lzop, postgresql, pv }:
-
-python3Packages.buildPythonApplication rec {
-  pname = "wal-e";
-  version = "1.1.1";
-
-  namePrefix = "";
-
-  src = fetchFromGitHub {
-    owner = "wal-e";
-    repo = "wal-e";
-    rev = "v${version}";
-    hash = "sha256-I6suHkAYzDtlNFNPH4SziY93Ryp+NTHkCBuojDvv+U4=";
-  };
-
-  # needs tox
-  doCheck = false;
-
-  propagatedBuildInputs = (with python3Packages; [
-    boto
-    gevent
-    google-cloud-storage
-  ]) ++ [
-    postgresql
-    lzop
-    pv
-  ];
-
-  meta = {
-    description = "Postgres WAL-shipping disaster recovery and replication toolkit";
-    mainProgram = "wal-e";
-    homepage = "https://github.com/wal-e/wal-e";
-    maintainers = [ ];
-    license = lib.licenses.bsd3;
-    platforms = lib.platforms.linux;
-  };
-}
diff --git a/pkgs/tools/misc/kargo/default.nix b/pkgs/tools/misc/kargo/default.nix
deleted file mode 100644
index 15310fb9350a8..0000000000000
--- a/pkgs/tools/misc/kargo/default.nix
+++ /dev/null
@@ -1,39 +0,0 @@
-{ lib, fetchurl, python3Packages }:
-
-with python3Packages;
-
-buildPythonApplication rec {
-  version = "0.4.8";
-  pname = "kargo";
-
-  src = fetchurl {
-    url = "mirror://pypi/k/kargo/${pname}-${version}.tar.gz";
-    sha256 = "1iq3vrmglag9gpsir03yz7556m0bz99nwb2mf594378cqzbr6db3";
-  };
-
-  propagatedBuildInputs = [
-    ansible-core
-    boto
-    cffi
-    cryptography
-    libcloud
-    markupsafe
-    netaddr
-    pyasn1
-    requests
-    setuptools
-  ];
-
-  checkPhase = ''
-    HOME=$TMPDIR $out/bin/kargo -v
-  '';
-
-  meta = with lib; {
-    homepage = "https://github.com/kubespray/kargo-cli";
-    description = "Tool helps to deploy a kubernetes cluster with Ansible";
-    platforms = platforms.all;
-    license = licenses.gpl3;
-    maintainers = [ ];
-    mainProgram = "kargo";
-  };
-}
diff --git a/pkgs/top-level/aliases.nix b/pkgs/top-level/aliases.nix
index b00cc4898cc30..5c26945985f4d 100644
--- a/pkgs/top-level/aliases.nix
+++ b/pkgs/top-level/aliases.nix
@@ -756,6 +756,7 @@ mapAliases ({
   kube3d = k3d; # Added 2022-0705
   kafkacat = kcat; # Added 2021-10-07
   kak-lsp = kakoune-lsp; # Added 2024-04-01
+  kargo = throw "kargo was removed as it is deprecated upstream and depends on the removed boto package"; # Added 2024-09-22
   kdbplus = throw "'kdbplus' has been removed from nixpkgs"; # Added 2024-05-06
   kdeconnect = plasma5Packages.kdeconnect-kde; # Added 2020-10-28
   keepassx = throw "KeePassX is no longer actively developed. Please consider KeePassXC as a maintained alternative."; # Added 2023-02-17
@@ -1558,6 +1559,7 @@ mapAliases ({
   tightvnc = throw "'tightvnc' has been removed as the version 1.3 is not maintained upstream anymore and is insecure"; # Added 2024-08-22
   tixati = throw "'tixati' has been removed from nixpkgs as it is unfree and unmaintained"; # Added 2023-03-17
   tkcvs = tkrev; # Added 2022-03-07
+  toil = throw "toil was removed as it was broken and requires obsolete versions of libraries"; # Added 2024-09-22
   tokodon = plasma5Packages.tokodon;
   tokyo-night-gtk = tokyonight-gtk-theme; # Added 2024-01-28
   tomcat_connectors = apacheHttpdPackages.mod_jk; # Added 2024-06-07
@@ -1651,6 +1653,7 @@ mapAliases ({
 
   ### W ###
   wakatime = wakatime-cli; # 2024-05-30
+  wal_e = throw "wal_e was removed as it is unmaintained upstream and depends on the removed boto package; upstream recommends using wal-g or pgbackrest"; # Added 2024-09-22
   waybar-hyprland = throw "waybar-hyprland has been removed: hyprland support is now built into waybar by default."; # Added 2023-08-21
   wayfireApplications-unwrapped = throw ''
     'wayfireApplications-unwrapped.wayfire' has been renamed to/replaced by 'wayfire'
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index 43b103ea11fae..c6d64eb987e26 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -9038,8 +9038,6 @@ with pkgs;
 
   k2pdfopt = callPackage ../applications/misc/k2pdfopt { };
 
-  kargo = callPackage ../tools/misc/kargo { };
-
   kazam = callPackage ../applications/video/kazam { };
 
   kalibrate-rtl = callPackage ../applications/radio/kalibrate-rtl { };
@@ -13582,8 +13580,6 @@ with pkgs;
 
   wego = callPackage ../applications/misc/wego { };
 
-  wal_e = callPackage ../tools/backup/wal-e { };
-
   wander = callPackage ../tools/admin/wander { };
 
   watchexec = callPackage ../tools/misc/watchexec {
@@ -18813,8 +18809,6 @@ with pkgs;
 
   todoist-electron = callPackage ../applications/misc/todoist-electron { };
 
-  toil = callPackage ../applications/science/misc/toil { };
-
   travis = callPackage ../development/tools/misc/travis { };
 
   tree-sitter = makeOverridable (callPackage ../development/tools/parsing/tree-sitter) {
@@ -37834,7 +37828,7 @@ with pkgs;
     # Not recommended; too fragile
     nixops_unstable_full;
 
-  # Useful with ofborg, e.g. commit prefix `nixops_unstablePlugins.nixops-aws: ...` to trigger automatically.
+  # Useful with ofborg, e.g. commit prefix `nixops_unstablePlugins.nixops-digitalocean: ...` to trigger automatically.
   nixops_unstablePlugins = recurseIntoAttrs nixops_unstable_minimal.availablePlugins;
 
   /*
diff --git a/pkgs/top-level/python-aliases.nix b/pkgs/top-level/python-aliases.nix
index 3bcb357458f85..e78e763003d7a 100644
--- a/pkgs/top-level/python-aliases.nix
+++ b/pkgs/top-level/python-aliases.nix
@@ -75,6 +75,7 @@ mapAliases ({
   bitcoin-price-api = throw "bitcoin-price-api has been removed, it was using setuptools 2to3 translation feautre, which has been removed in setuptools 58"; # added 2022-02-15
   BlinkStick = blinkstick; # added 2023-02-19
   blockdiagcontrib-cisco = throw "blockdiagcontrib-cisco is not compatible with blockdiag 2.0.0 and has been removed."; # added 2020-11-29
+  boto = throw "boto was removed as it is deprecated upstream, had not been updated since 2018, and failed to build; please use boto3 and botocore"; # Added 2024-09-22
   bsblan = python-bsblan; # added 2022-11-04
   btchip = btchip-python; # added 2023-03-03
   buildbot = throw "use pkgs.buildbot instead"; # added 2022-04-07
@@ -219,6 +220,7 @@ mapAliases ({
   fritzprofiles = throw "fritzprofiles was removed from nixpkgs, because it was removed as dependency of home-assistant for which it was pacakged."; # added 2024-01-05
   garages-amsterdam = throw "garages-amsterdam has been renamed odp-amsterdam."; # added 2023-01-04
   garminconnect-ha = garminconnect; # added 2022-02-05
+  gcs-oauth2-boto-plugin = throw "gcs-oauth2-boto-plugin was removed as it depends on the removed boto package"; # Added 2024-09-22
   gdtoolkit = throw "gdtoolkit has been promoted to a top-level attribute name: `pkgs.gdtoolkit`"; # added 2023-02-15
   GeoIP = geoip; # added 2023-02-19
   gigalixir = throw "gigalixir has been promoted to a top-level attribute name: `pkgs.gigalixir`"; # Added 2022-10-02
@@ -519,6 +521,7 @@ mapAliases ({
   pyxb = throw "pyxb has been removed, its last release was in 2017 and it has finally been archived in April 2023."; # added 2024-01-05
   pyzufall =  throw "pyzufall was removed, because it is no longer maintained"; # added 2024-05-14
   qasm2image = throw "qasm2image is no longer maintained (since November 2018), and is not compatible with the latest pythonPackages.qiskit versions."; # added 2020-12-09
+  qds-sdk = throw "qds-sdk was removed as it is unmaintained upstream and depends on the removed boto package"; # Added 2024-09-22
   qds_sdk = qds-sdk; # added 2023-10-21
   Quandl = quandl; # added 2023-02-19
   querystring_parser = querystring-parser; # added 2024-01-07
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index a9231aecd6e8e..78429d4584007 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -1790,8 +1790,6 @@ self: super: with self; {
 
   boto3-stubs = callPackage ../development/python-modules/boto3-stubs { };
 
-  boto = callPackage ../development/python-modules/boto { };
-
   botocore = callPackage ../development/python-modules/botocore { };
 
   botocore-stubs = callPackage ../development/python-modules/botocore-stubs { };
@@ -4873,8 +4871,6 @@ self: super: with self; {
 
   gcovr = callPackage ../development/python-modules/gcovr { };
 
-  gcs-oauth2-boto-plugin = callPackage ../development/python-modules/gcs-oauth2-boto-plugin { };
-
   gcsa = callPackage ../development/python-modules/gcsa { };
 
   gcsfs = callPackage ../development/python-modules/gcsfs { };
@@ -13153,8 +13149,6 @@ self: super: with self; {
 
   qdrant-client = callPackage ../development/python-modules/qdrant-client { };
 
-  qds-sdk = callPackage ../development/python-modules/qds-sdk { };
-
   qgrid = callPackage ../development/python-modules/qgrid { };
 
   qemu = callPackage ../development/python-modules/qemu {