diff --git a/pkgs/applications/audio/ncmpc/default.nix b/pkgs/applications/audio/ncmpc/default.nix
index ef0bb75b2ec00..cb0f35ebc156c 100644
--- a/pkgs/applications/audio/ncmpc/default.nix
+++ b/pkgs/applications/audio/ncmpc/default.nix
@@ -1,11 +1,7 @@
 { stdenv, fetchFromGitHub, meson, ninja, pkgconfig, glib, ncurses
 , mpd_clientlib, gettext }:
 
-let
-  rpath = stdenv.lib.makeLibraryPath [
-    glib ncurses mpd_clientlib
-  ];
-in stdenv.mkDerivation rec {
+stdenv.mkDerivation rec {
   name = "ncmpc-${version}";
   version = "0.28";
 
@@ -19,12 +15,6 @@ in stdenv.mkDerivation rec {
   buildInputs = [ glib ncurses mpd_clientlib ];
   nativeBuildInputs = [ meson ninja pkgconfig gettext ];
 
-  postFixup = ''
-    for elf in "$out"/bin/*; do
-      patchelf --set-rpath '${rpath}':"$out/lib" "$elf"
-    done
-  '';
-
   meta = with stdenv.lib; {
     description = "Curses-based interface for MPD (music player daemon)";
     homepage    = http://www.musicpd.org/clients/ncmpc/;
diff --git a/pkgs/development/libraries/appstream-glib/default.nix b/pkgs/development/libraries/appstream-glib/default.nix
index e07e1fc390877..1c97b879a1894 100644
--- a/pkgs/development/libraries/appstream-glib/default.nix
+++ b/pkgs/development/libraries/appstream-glib/default.nix
@@ -3,15 +3,7 @@
 , gobjectIntrospection, sqlite, libsoup, gcab, attr, acl, docbook_xsl
 , libuuid, json_glib, autoconf-archive, meson, gperf, ninja, gdk_pixbuf
 }:
-let rpath = stdenv.lib.makeLibraryPath
-      [ libuuid.out
-        glib
-        libsoup
-        gdk_pixbuf
-        libarchive.lib
-        gcab
-      ];
-in stdenv.mkDerivation rec {
+stdenv.mkDerivation rec {
   name = "appstream-glib-0.7.2";
 
   src = fetchFromGitHub {
@@ -28,12 +20,6 @@ in stdenv.mkDerivation rec {
   propagatedBuildInputs = [ gtk3 ];
   mesonFlags = [ "-Denable-rpm=false" "-Denable-stemmer=false" "-Denable-dep11=false" ];
 
-  postFixup = ''
-    for elf in "$out"/bin/* "$out"/lib/*.so; do
-      patchelf --set-rpath '${rpath}':"$out/lib" "$elf"
-    done
-  '';
-
   meta = with stdenv.lib; {
     description = "Objects and helper methods to read and write AppStream metadata";
     homepage    = https://github.com/hughsie/appstream-glib;
diff --git a/pkgs/tools/filesystems/sshfs-fuse/default.nix b/pkgs/tools/filesystems/sshfs-fuse/default.nix
index 7d251d2e00d02..eebe3076c98a7 100644
--- a/pkgs/tools/filesystems/sshfs-fuse/default.nix
+++ b/pkgs/tools/filesystems/sshfs-fuse/default.nix
@@ -4,7 +4,6 @@
 
 let
   inherit (stdenv.lib) optional;
-  rpath = stdenv.lib.makeLibraryPath [ fuse3 glib ];
 in stdenv.mkDerivation rec {
   version = "3.3.1";
   name = "sshfs-fuse-${version}";
@@ -30,10 +29,6 @@ in stdenv.mkDerivation rec {
     ln -sf $out/bin/sshfs $out/sbin/mount.sshfs
   '';
 
-  postFixup = ''
-       patchelf --set-rpath '${rpath}' "$out/bin/sshfs"
-  '';
-
   meta = with stdenv.lib; {
     inherit (src.meta) homepage;
     description = "FUSE-based filesystem that allows remote filesystems to be mounted over SSH";