diff --git a/pkgs/applications/video/vlc/default.nix b/pkgs/applications/video/vlc/default.nix
index 8f2358fdd6abb..cc19839bde742 100644
--- a/pkgs/applications/video/vlc/default.nix
+++ b/pkgs/applications/video/vlc/default.nix
@@ -44,7 +44,7 @@
 , libmtp
 , liboggz
 , libopus
-, libplacebo
+, libplacebo_5
 , libpulseaudio
 , libraw1394
 , librsvg
@@ -164,7 +164,7 @@ stdenv.mkDerivation (finalAttrs: {
     libmtp
     liboggz
     libopus
-    libplacebo
+    libplacebo_5
     libpulseaudio
     libraw1394
     librsvg
diff --git a/pkgs/development/libraries/ffmpeg/generic.nix b/pkgs/development/libraries/ffmpeg/generic.nix
index 5ae6469c74353..b6ef374626c54 100644
--- a/pkgs/development/libraries/ffmpeg/generic.nix
+++ b/pkgs/development/libraries/ffmpeg/generic.nix
@@ -213,6 +213,7 @@
 , libopenmpt
 , libopus
 , libplacebo
+, libplacebo_5
 , libpulseaudio
 , libraw1394
 , librsvg
@@ -577,7 +578,7 @@ stdenv.mkDerivation (finalAttrs: {
   ++ optionals withIconv [ libiconv ] # On Linux this should be in libc, do we really need it?
   ++ optionals withJack [ libjack2 ]
   ++ optionals withLadspa [ ladspaH ]
-  ++ optionals withLibplacebo [ libplacebo vulkan-headers ]
+  ++ optionals withLibplacebo [ (if (lib.versionAtLeast version "6.1") then libplacebo else libplacebo_5) vulkan-headers ]
   ++ optionals withLzma [ xz ]
   ++ optionals withMfx [ intel-media-sdk ]
   ++ optionals withModplug [ libmodplug ]
diff --git a/pkgs/development/libraries/libplacebo/5.nix b/pkgs/development/libraries/libplacebo/5.nix
new file mode 100644
index 0000000000000..f307a869e940b
--- /dev/null
+++ b/pkgs/development/libraries/libplacebo/5.nix
@@ -0,0 +1,77 @@
+{ lib
+, stdenv
+, fetchFromGitLab
+, meson
+, ninja
+, pkg-config
+, python3Packages
+, vulkan-headers
+, vulkan-loader
+, shaderc
+, lcms2
+, libGL
+, libX11
+, libunwind
+, libdovi
+}:
+
+stdenv.mkDerivation rec {
+  pname = "libplacebo";
+  version = "5.264.1";
+
+  src = fetchFromGitLab {
+    domain = "code.videolan.org";
+    owner = "videolan";
+    repo = pname;
+    rev = "v${version}";
+    hash = "sha256-YEefuEfJURi5/wswQKskA/J1UGzessQQkBpltJ0Spq8=";
+  };
+
+  nativeBuildInputs = [
+    meson
+    ninja
+    pkg-config
+    vulkan-headers
+    python3Packages.jinja2
+    python3Packages.glad2
+  ];
+
+  buildInputs = [
+    vulkan-loader
+    shaderc
+    lcms2
+    libGL
+    libX11
+    libunwind
+    libdovi
+  ];
+
+  mesonFlags = with lib; [
+    (mesonOption "vulkan-registry" "${vulkan-headers}/share/vulkan/registry/vk.xml")
+    (mesonBool "demos" false) # Don't build and install the demo programs
+    (mesonEnable "d3d11" false) # Disable the Direct3D 11 based renderer
+    (mesonEnable "glslang" false) # rely on shaderc for GLSL compilation instead
+  ] ++ optionals stdenv.isDarwin [
+    (mesonEnable "unwind" false) # libplacebo doesn’t build with `darwin.libunwind`
+  ];
+
+  postPatch = ''
+    substituteInPlace meson.build \
+      --replace 'python_env.append' '#'
+  '';
+
+  meta = with lib; {
+    description = "Reusable library for GPU-accelerated video/image rendering primitives";
+    longDescription = ''
+      Reusable library for GPU-accelerated image/view processing primitives and
+      shaders, as well a batteries-included, extensible, high-quality rendering
+      pipeline (similar to mpv's vo_gpu). Supports Vulkan, OpenGL and Metal (via
+      MoltenVK).
+    '';
+    homepage = "https://code.videolan.org/videolan/libplacebo";
+    changelog = "https://code.videolan.org/videolan/libplacebo/-/tags/v${version}";
+    license = licenses.lgpl21Plus;
+    maintainers = with maintainers; [ primeos tadeokondrak ];
+    platforms = platforms.all;
+  };
+}
diff --git a/pkgs/development/libraries/libplacebo/default.nix b/pkgs/development/libraries/libplacebo/default.nix
index 60a3f89895784..c303ffb295589 100644
--- a/pkgs/development/libraries/libplacebo/default.nix
+++ b/pkgs/development/libraries/libplacebo/default.nix
@@ -10,21 +10,22 @@
 , shaderc
 , lcms2
 , libGL
-, xorg
+, libX11
 , libunwind
 , libdovi
+, xxHash
 }:
 
 stdenv.mkDerivation rec {
   pname = "libplacebo";
-  version = "5.264.1";
+  version = "6.338.1";
 
   src = fetchFromGitLab {
     domain = "code.videolan.org";
     owner = "videolan";
     repo = pname;
     rev = "v${version}";
-    hash = "sha256-YEefuEfJURi5/wswQKskA/J1UGzessQQkBpltJ0Spq8=";
+    hash = "sha256-NZmwR3+lIC2PF+k+kqCjoMYkMM/PKOJmDwAq7t6YONY=";
   };
 
   nativeBuildInputs = [
@@ -41,18 +42,19 @@ stdenv.mkDerivation rec {
     shaderc
     lcms2
     libGL
-    xorg.libX11
+    libX11
     libunwind
     libdovi
+    xxHash
   ];
 
-  mesonFlags = [
-    "-Dvulkan-registry=${vulkan-headers}/share/vulkan/registry/vk.xml"
-    "-Ddemos=false" # Don't build and install the demo programs
-    "-Dd3d11=disabled" # Disable the Direct3D 11 based renderer
-    "-Dglslang=disabled" # rely on shaderc for GLSL compilation instead
-  ] ++ lib.optionals stdenv.isDarwin [
-    "-Dunwind=disabled" # libplacebo doesn’t build with `darwin.libunwind`
+  mesonFlags = with lib; [
+    (mesonOption "vulkan-registry" "${vulkan-headers}/share/vulkan/registry/vk.xml")
+    (mesonBool "demos" false) # Don't build and install the demo programs
+    (mesonEnable "d3d11" false) # Disable the Direct3D 11 based renderer
+    (mesonEnable "glslang" false) # rely on shaderc for GLSL compilation instead
+  ] ++ optionals stdenv.isDarwin [
+    (mesonEnable "unwind" false) # libplacebo doesn’t build with `darwin.libunwind`
   ];
 
   postPatch = ''
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index d9d15824e3e92..aec5a259a7d67 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -23418,6 +23418,7 @@ with pkgs;
     inherit (darwin.apple_sdk.frameworks) Foundation;
   };
 
+  libplacebo_5 = callPackage ../development/libraries/libplacebo/5.nix { };
   libplacebo = callPackage ../development/libraries/libplacebo { };
 
   libpng = callPackage ../development/libraries/libpng { };