diff --git a/pkgs/development/python-modules/imageio/default.nix b/pkgs/development/python-modules/imageio/default.nix
index d919c00e74a6c..6989a12bf8650 100644
--- a/pkgs/development/python-modules/imageio/default.nix
+++ b/pkgs/development/python-modules/imageio/default.nix
@@ -26,7 +26,7 @@ buildPythonPackage rec {
     hash = "sha256-XbUIe+XIFOz34sfTChoVyX7Kl9jCbzHdxU12fUpDvOg=";
   };
 
-  patches = [
+  patches = lib.optionals (!stdenv.isDarwin) [
     (substituteAll {
       src = ./libgl-path.patch;
       libgl = "${libGL.out}/lib/libGL${stdenv.hostPlatform.extensions.sharedLibrary}";