diff --git a/pkgs/applications/audio/myxer/default.nix b/pkgs/applications/audio/myxer/default.nix
deleted file mode 100644
index 5617282135546..0000000000000
--- a/pkgs/applications/audio/myxer/default.nix
+++ /dev/null
@@ -1,40 +0,0 @@
-{ stdenv
-, lib
-, rustPlatform
-, fetchFromGitHub
-, pkg-config
-, libpulseaudio
-, glib
-, pango
-, gtk3
-}:
-
-rustPlatform.buildRustPackage rec {
-  pname = "myxer";
-  version = "1.2.1";
-
-  src = fetchFromGitHub {
-    owner = "Aurailus";
-    repo = pname;
-    rev = version;
-    sha256 = "0bnhpzmx4yyasv0j7bp31q6jm20p0qwcia5bzmpkz1jhnc27ngix";
-  };
-
-  cargoSha256 = "1cyh0nk627sgyr78rcnhj7af5jcahvjkiv5sz7xwqfdhvx5kqsk5";
-
-  nativeBuildInputs = [ pkg-config ];
-
-  buildInputs = [ libpulseaudio glib pango gtk3 ];
-
-  # Currently no tests are implemented, so we avoid building the package twice
-  doCheck = false;
-
-  meta = with lib; {
-    broken = (stdenv.isLinux && stdenv.isAarch64);
-    description = "A modern Volume Mixer for PulseAudio";
-    homepage = "https://github.com/Aurailus/Myxer";
-    license = licenses.gpl3Only;
-    maintainers = with maintainers; [ erin ];
-    platforms = platforms.linux;
-  };
-}
diff --git a/pkgs/top-level/aliases.nix b/pkgs/top-level/aliases.nix
index 1fc44abf1ab8b..b8b55b93a71aa 100644
--- a/pkgs/top-level/aliases.nix
+++ b/pkgs/top-level/aliases.nix
@@ -897,6 +897,7 @@ mapAliases ({
   mx = throw "graalvm8 and its tools were deprecated in favor of graalvm8-ce"; # Added 2021-10-15
   mxisd = throw "mxisd has been removed from nixpkgs as it has reached end of life, see https://github.com/kamax-matrix/mxisd/blob/535e0a5b96ab63cb0ddef90f6f42c5866407df95/EOL.md#end-of-life-notice . ma1sd may be a suitable alternative"; # Added 2021-04-15
   mysqlWorkbench = throw "'mysqlWorkbench' has been renamed to/replaced by 'mysql-workbench'"; # Converted to throw 2022-02-22
+  myxer = throw "Myxer has been removed from nixpkgs, as it has been unmaintained since Jul 31, 2021"; # Added 2022-06-08
 
   ### N ###
 
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index 80f3f63f335fe..aef1b0d68b91b 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -28858,8 +28858,6 @@ with pkgs;
 
   pamixer = callPackage ../applications/audio/pamixer { };
 
-  myxer = callPackage ../applications/audio/myxer { };
-
   ncpamixer = callPackage ../applications/audio/ncpamixer { };
 
   pan = callPackage ../applications/networking/newsreaders/pan { };