diff --git a/pkgs/data/misc/osinfo-db/default.nix b/pkgs/data/misc/osinfo-db/default.nix
index 4af6f3b4db402..ac4c5aba3b175 100644
--- a/pkgs/data/misc/osinfo-db/default.nix
+++ b/pkgs/data/misc/osinfo-db/default.nix
@@ -30,7 +30,7 @@ stdenv.mkDerivation rec {
     homepage = "https://gitlab.com/libosinfo/osinfo-db/";
     changelog = "https://gitlab.com/libosinfo/osinfo-db/-/commits/v${version}";
     license = licenses.gpl2Plus;
-    platforms = platforms.linux;
+    platforms = platforms.unix;
     maintainers = [ maintainers.bjornfor ];
   };
 }
diff --git a/pkgs/development/libraries/libosinfo/default.nix b/pkgs/development/libraries/libosinfo/default.nix
index a1dd23357decd..e999ddd4b6b99 100644
--- a/pkgs/development/libraries/libosinfo/default.nix
+++ b/pkgs/development/libraries/libosinfo/default.nix
@@ -79,7 +79,7 @@ stdenv.mkDerivation rec {
     homepage = "https://libosinfo.org/";
     changelog = "https://gitlab.com/libosinfo/libosinfo/-/blob/v${version}/NEWS";
     license = licenses.lgpl2Plus;
-    platforms = platforms.linux;
+    platforms = platforms.unix;
     maintainers = [ maintainers.bjornfor ];
   };
 }
diff --git a/pkgs/development/libraries/libvirt-glib/default.nix b/pkgs/development/libraries/libvirt-glib/default.nix
index f86edf1bfbcb5..84b66f05be795 100644
--- a/pkgs/development/libraries/libvirt-glib/default.nix
+++ b/pkgs/development/libraries/libvirt-glib/default.nix
@@ -46,10 +46,11 @@ stdenv.mkDerivation rec {
   ];
 
   buildInputs = [
-    libcap_ng
     libvirt
     libxml2
     gobject-introspection
+  ] ++ lib.optionals stdenv.isLinux [
+    libcap_ng
   ];
 
   strictDeps = true;
@@ -66,6 +67,6 @@ stdenv.mkDerivation rec {
     '';
     homepage = "https://libvirt.org/";
     license = licenses.lgpl2Plus;
-    platforms = platforms.linux;
+    platforms = platforms.unix;
   };
 }
diff --git a/pkgs/development/libraries/libvirt/default.nix b/pkgs/development/libraries/libvirt/default.nix
index 42ccf8fddcf68..4fbbcc8d3c64e 100644
--- a/pkgs/development/libraries/libvirt/default.nix
+++ b/pkgs/development/libraries/libvirt/default.nix
@@ -140,7 +140,9 @@ stdenv.mkDerivation rec {
     # delete only the first occurrence of this
     sed -i '0,/qemuxml2argvtest/{/qemuxml2argvtest/d;}' tests/meson.build
   '' + optionalString isDarwin ''
-    sed -i '/qemucapabilitiestest/d' tests/meson.build
+    sed -i tests/meson.build \
+      -e '/qemucapabilitiestest/d' \
+      -e '/vircryptotest/d'
   '';
 
 
diff --git a/pkgs/development/libraries/spice-gtk/default.nix b/pkgs/development/libraries/spice-gtk/default.nix
index db5db61c6e991..8d914ed35bec7 100644
--- a/pkgs/development/libraries/spice-gtk/default.nix
+++ b/pkgs/development/libraries/spice-gtk/default.nix
@@ -33,7 +33,7 @@
 , vala
 , wayland-protocols
 , zlib
-, withPolkit ? true
+, withPolkit ? (!stdenv.isDarwin)
 }:
 
 # If this package is built with polkit support (withPolkit=true),
@@ -78,6 +78,8 @@ stdenv.mkDerivation rec {
       "# meson.add_install_script('../build-aux/setcap-or-suid',"
   '';
 
+  NIX_CFLAGS_COMPILE = if stdenv.isDarwin then "-Wno-unused-function -Wno-missing-field-initializers" else null;
+
   nativeBuildInputs = [
     docbook_xsl
     gettext
@@ -104,20 +106,18 @@ stdenv.mkDerivation rec {
     gtk3
     json-glib
     libcacard
-    libcap_ng
-    libdrm
     libjpeg_turbo
     libopus
     libusb1
     lz4
     openssl
-    phodav
     pixman
     spice-protocol
     usbredir
-    wayland-protocols
     zlib
-  ] ++ lib.optionals withPolkit [ polkit acl ] ;
+  ]
+  ++ lib.optionals withPolkit [ polkit acl ]
+  ++ lib.optionals (!stdenv.isDarwin) [ libcap_ng libdrm phodav wayland-protocols ];
 
   PKG_CONFIG_POLKIT_GOBJECT_1_POLICYDIR = "${placeholder "out"}/share/polkit-1/actions";
 
@@ -126,6 +126,9 @@ stdenv.mkDerivation rec {
     "-Dusb-ids-path=${hwdata}/share/hwdata/usb.ids"
   ] ++ lib.optionals (!withPolkit) [
     "-Dpolkit=disabled"
+  ] ++ lib.optionals stdenv.isDarwin [
+    "-Dwebdav=disabled" # no phodav
+    "-Dlibcap-ng=disabled"
   ];
 
   meta = with lib; {
@@ -140,6 +143,6 @@ stdenv.mkDerivation rec {
     homepage = "https://www.spice-space.org/";
     license = licenses.lgpl21;
     maintainers = [ maintainers.xeji ];
-    platforms = platforms.linux;
+    platforms = platforms.unix;
   };
 }
diff --git a/pkgs/development/libraries/usbredir/default.nix b/pkgs/development/libraries/usbredir/default.nix
index 60f532b9779a1..797c32cb6d2d9 100644
--- a/pkgs/development/libraries/usbredir/default.nix
+++ b/pkgs/development/libraries/usbredir/default.nix
@@ -48,6 +48,6 @@ stdenv.mkDerivation rec {
     homepage = "https://www.spice-space.org/usbredir.html";
     license = licenses.lgpl21Plus;
     maintainers = with maintainers; [ offline ];
-    platforms = platforms.linux;
+    platforms = platforms.unix;
   };
 }
diff --git a/pkgs/development/libraries/vte/default.nix b/pkgs/development/libraries/vte/default.nix
index 16a800110942c..f113081cc24df 100644
--- a/pkgs/development/libraries/vte/default.nix
+++ b/pkgs/development/libraries/vte/default.nix
@@ -78,6 +78,8 @@ stdenv.mkDerivation rec {
 
   mesonFlags = lib.optionals (!systemdSupport) [
     "-D_systemd=false"
+  ] ++ lib.optionals stdenv.isDarwin [
+    "-D_b_symbolic_functions=false"
   ];
 
   postPatch = ''
diff --git a/pkgs/servers/pulseaudio/default.nix b/pkgs/servers/pulseaudio/default.nix
index b0ccd5f76354d..1b98c2e32c47d 100644
--- a/pkgs/servers/pulseaudio/default.nix
+++ b/pkgs/servers/pulseaudio/default.nix
@@ -1,7 +1,7 @@
 { lib, stdenv, fetchurl, fetchpatch, pkg-config
 , libsndfile, libtool, makeWrapper, perlPackages
 , xorg, libcap, alsa-lib, glib, dconf
-, avahi, libjack2, libasyncns, lirc, dbus
+, avahi, libjack2, libasyncns, lirc, libintl, dbus
 , sbc, bluez5, udev, openssl, fftwFloat
 , soxr, speexdsp, systemd, webrtc-audio-processing
 , check, meson, ninja, m4
@@ -56,7 +56,7 @@ stdenv.mkDerivation rec {
   buildInputs =
     [ libtool libsndfile soxr speexdsp fftwFloat check ]
     ++ lib.optionals stdenv.isLinux [ glib dbus ]
-    ++ lib.optionals stdenv.isDarwin [ AudioUnit Cocoa CoreServices ]
+    ++ lib.optionals stdenv.isDarwin [ AudioUnit Cocoa CoreServices libintl ]
     ++ lib.optionals (!libOnly) (
       [ libasyncns webrtc-audio-processing ]
       ++ lib.optional jackaudioSupport libjack2
diff --git a/pkgs/tools/admin/gtk-vnc/default.nix b/pkgs/tools/admin/gtk-vnc/default.nix
index 060c95a8f7672..e478d905483bf 100644
--- a/pkgs/tools/admin/gtk-vnc/default.nix
+++ b/pkgs/tools/admin/gtk-vnc/default.nix
@@ -67,6 +67,6 @@ stdenv.mkDerivation rec {
     homepage = "https://wiki.gnome.org/Projects/gtk-vnc";
     license = licenses.lgpl2Plus;
     maintainers = with maintainers; [ raskin offline ];
-    platforms = platforms.linux;
+    platforms = platforms.unix;
   };
 }
diff --git a/pkgs/tools/misc/osinfo-db-tools/default.nix b/pkgs/tools/misc/osinfo-db-tools/default.nix
index 189f549e172f1..cf0ab2776ba57 100644
--- a/pkgs/tools/misc/osinfo-db-tools/default.nix
+++ b/pkgs/tools/misc/osinfo-db-tools/default.nix
@@ -51,7 +51,7 @@ stdenv.mkDerivation rec {
     homepage = "https://libosinfo.org/";
     changelog = "https://gitlab.com/libosinfo/osinfo-db-tools/-/blob/v${version}/NEWS";
     license = licenses.lgpl2Plus;
-    platforms = platforms.linux;
+    platforms = platforms.unix;
     maintainers = [ maintainers.bjornfor ];
   };
 }