diff --git a/pkgs/development/interpreters/python/pypy/prebuilt.nix b/pkgs/development/interpreters/python/pypy/prebuilt.nix
index f301fd15f09ca..460af1cc67b4f 100644
--- a/pkgs/development/interpreters/python/pypy/prebuilt.nix
+++ b/pkgs/development/interpreters/python/pypy/prebuilt.nix
@@ -1,4 +1,5 @@
-{ stdenv
+{ lib
+, stdenv
 , fetchurl
 , python-setup-hook
 , self
@@ -31,9 +32,15 @@ let
     implementation = "pypy";
     libPrefix = "pypy${pythonVersion}";
     executable = "pypy${if isPy3k then "3" else ""}";
-    pythonForBuild = self; # Not possible to cross-compile with.
     sitePackages = "site-packages";
     hasDistutilsCxxPatch = false;
+
+    # Not possible to cross-compile with.
+    pythonOnBuildForBuild = throw "${pname} does not support cross compilation";
+    pythonOnBuildForHost = self;
+    pythonOnBuildForTarget = throw "${pname} does not support cross compilation";
+    pythonOnHostForHost = throw "${pname} does not support cross compilation";
+    pythonOnTargetForTarget = throw "${pname} does not support cross compilation";
   };
   pname = "${passthru.executable}_prebuilt";
   version = with sourceVersion; "${major}.${minor}.${patch}";