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Implement a second iteration to the pipeline #42

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nictru opened this issue Feb 16, 2024 · 0 comments · Fixed by #55
Closed

Implement a second iteration to the pipeline #42

nictru opened this issue Feb 16, 2024 · 0 comments · Fixed by #55
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nictru commented Feb 16, 2024

After creating a basic atlas and manual annotation, we can subset to certain subpopulations (e.g. Myeloid cells) and run the Neighbors-Leiden-UMAP section again on only this subset.

The resulting UMAPs can then be explored using the embedding switcher, since switching between integration methods does not make sense for this.

A reason for this is that if there is a very high number of cells, closely related cell types are not clearly distinguishable in the UMAP any more, although in the clustering it kind of works

@nictru nictru added the enhancement New feature or request label Feb 16, 2024
@nictru nictru added this to the Budva milestone Feb 16, 2024
@nictru nictru self-assigned this Feb 16, 2024
@nictru nictru linked a pull request Apr 5, 2024 that will close this issue
@nictru nictru closed this as completed in #55 Apr 5, 2024
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