diff --git a/Formula/itk.rb b/Formula/itk.rb
new file mode 100644
index 000000000000..0df9807b727e
--- /dev/null
+++ b/Formula/itk.rb
@@ -0,0 +1,81 @@
+class Itk < Formula
+  desc "Insight Toolkit is a toolkit for performing registration and segmentation"
+  homepage "https://www.itk.org"
+  url "https://downloads.sourceforge.net/project/itk/itk/4.13/InsightToolkit-4.13.2.tar.gz"
+  sha256 "d8760b279de20497c432e7cdf97ed349277da1ae435be1f6f0f00fbe8d4938c1"
+  head "git://itk.org/ITK.git"
+
+  depends_on "cmake" => :build
+  depends_on "fftw"
+  depends_on "gdcm"
+  depends_on "hdf5"
+  depends_on "jpeg"
+  depends_on "libpng"
+  depends_on "libtiff"
+  depends_on "vtk"
+
+  # Patch needed to install MINC's cmake files into #{lib}/cmake not #{lib}
+  # PR Submitted to ITK upstream: https://github.com/InsightSoftwareConsortium/ITK/pull/754
+  patch do
+    url "https://raw.githubusercontent.com/Homebrew/formula-patches/master/itk/4.13.2-MINC-cmake-files-location.patch"
+    sha256 "7ec6a55e83109332d636298e7339793ec338969211533467ff0fbfb7c1c27883"
+  end
+
+  def install
+    args = std_cmake_args + %W[
+      -DBUILD_SHARED_LIBS=ON
+      -DBUILD_TESTING=OFF
+      -DCMAKE_INSTALL_RPATH:STRING=#{lib}
+      -DCMAKE_INSTALL_NAME_DIR:STRING=#{lib}
+      -DITK_USE_64BITS_IDS=ON
+      -DITK_USE_STRICT_CONCEPT_CHECKING=ON
+      -DITK_USE_SYSTEM_ZLIB=ON
+      -DITK_USE_SYSTEM_EXPAT=ON
+      -DModule_SCIFIO=ON
+      -DITKV3_COMPATIBILITY:BOOL=OFF
+      -DITK_USE_SYSTEM_FFTW=ON
+      -DITK_USE_FFTWF=ON
+      -DITK_USE_FFTWD=ON
+      -DITK_USE_SYSTEM_HDF5=ON
+      -DITK_USE_SYSTEM_JPEG=ON
+      -DITK_USE_SYSTEM_PNG=ON
+      -DITK_USE_SYSTEM_TIFF=ON
+      -DITK_USE_SYSTEM_GDCM=ON
+      -DITK_LEGACY_REMOVE=ON
+      -DModule_ITKLevelSetsv4Visualization=ON
+      -DModule_ITKReview=ON
+      -DModule_ITKVtkGlue=ON
+      -DITK_USE_GPU=ON
+    ]
+
+    mkdir "build" do
+      system "cmake", "..", *args
+      system "make"
+      system "make", "install"
+    end
+  end
+
+  test do
+    (testpath/"test.cxx").write <<-EOS
+      #include "itkImage.h"
+      int main(int argc, char* argv[])
+      {
+        typedef itk::Image<unsigned short, 3> ImageType;
+        ImageType::Pointer image = ImageType::New();
+        image->Update();
+        return EXIT_SUCCESS;
+      }
+    EOS
+
+    v = version.to_s.split(".")[0..1].join(".")
+    # Build step
+    system ENV.cxx, "-isystem", "#{include}/ITK-#{v}", "-o", "test.cxx.o", "-c", "test.cxx"
+    # Linking step
+    system ENV.cxx, "test.cxx.o", "-o", "test",
+                    "#{lib}/libITKCommon-#{v}.1.dylib",
+                    "#{lib}/libITKVNLInstantiation-#{v}.1.dylib",
+                    "#{lib}/libitkvnl_algo-#{v}.1.dylib",
+                    "#{lib}/libitkvnl-#{v}.1.dylib"
+    system "./test"
+  end
+end