diff --git a/hathor/p2p/node_sync.py b/hathor/p2p/node_sync.py
index 9de01413c..0ae5d51c3 100644
--- a/hathor/p2p/node_sync.py
+++ b/hathor/p2p/node_sync.py
@@ -207,6 +207,9 @@ def __init__(self, protocol: 'HathorProtocol', downloader: Downloader, reactor:
         self.call_later_id: Optional[IDelayedCall] = None
         self.call_later_interval: int = 1  # seconds
 
+        # Keep track of call laters.
+        self._send_tips_call_later: list[IDelayedCall] = []
+
         # Timestamp of the peer's latest block (according to the peer itself)
         self.peer_timestamp: int = 0
 
@@ -284,6 +287,9 @@ def stop(self) -> None:
             self.send_data_queue.stop()
         if self.call_later_id and self.call_later_id.active():
             self.call_later_id.cancel()
+        for call_later in self._send_tips_call_later:
+            if call_later.active():
+                call_later.cancel()
         # XXX: force remove this connection from _all_ pending downloads
         self.downloader.drop_connection(self)
 
@@ -617,13 +623,24 @@ def send_tips(self, timestamp: Optional[int] = None, include_hashes: bool = Fals
         """Try to send a TIPS message. If rate limit has been reached, it schedules to send it later."""
         if not self.global_rate_limiter.add_hit(self.GlobalRateLimiter.SEND_TIPS):
             self.log.debug('send_tips throttled')
-            self.reactor.callLater(1, self.send_tips, timestamp, include_hashes, offset)
+            self._send_tips_call_later.append(
+                self.reactor.callLater(
+                    1, self.send_tips, timestamp, include_hashes, offset
+                )
+            )
             return
         self._send_tips(timestamp, include_hashes, offset)
 
     def _send_tips(self, timestamp: Optional[int] = None, include_hashes: bool = False, offset: int = 0) -> None:
         """ Send a TIPS message.
         """
+        # Filter for active delayed calls once one is executing
+        self._send_tips_call_later = [
+            call_later
+            for call_later in self._send_tips_call_later
+            if call_later.active()
+        ]
+
         if timestamp is None:
             timestamp = self.manager.tx_storage.latest_timestamp
 
diff --git a/hathor/simulator/simulator.py b/hathor/simulator/simulator.py
index b17e0a074..878a5d2be 100644
--- a/hathor/simulator/simulator.py
+++ b/hathor/simulator/simulator.py
@@ -219,6 +219,9 @@ def get_peer(self, name: str) -> HathorManager:
     def add_connection(self, conn: 'FakeConnection') -> None:
         self._connections.append(conn)
 
+    def remove_connection(self, conn: 'FakeConnection') -> None:
+        self._connections.remove(conn)
+
     def _run(self, interval: float, step: float, status_interval: float) -> Generator[None, None, None]:
         """ Implementation of run, yields at every step to allow verifications like in run_until_complete
         """
diff --git a/tests/p2p/test_sync_rate_limiter.py b/tests/p2p/test_sync_rate_limiter.py
index df0020841..3d7d99291 100644
--- a/tests/p2p/test_sync_rate_limiter.py
+++ b/tests/p2p/test_sync_rate_limiter.py
@@ -1,4 +1,6 @@
-from unittest.mock import MagicMock
+from unittest.mock import MagicMock, Mock
+
+from twisted.python.failure import Failure
 
 from hathor.simulator import FakeConnection
 from hathor.simulator.trigger import StopAfterNMinedBlocks
@@ -25,8 +27,8 @@ def test_sync_rate_limiter(self):
 
         connected_peers2 = list(manager2.connections.connected_peers.values())
         self.assertEqual(1, len(connected_peers2))
-        protocol2 = connected_peers2[0]
-        sync2 = protocol2.state.sync_manager
+        protocol1 = connected_peers2[0]
+        sync2 = protocol1.state.sync_manager
         sync2._send_tips = MagicMock()
 
         for i in range(100):
@@ -40,6 +42,91 @@ def test_sync_rate_limiter(self):
         self.simulator._clock.advance(2000)
         self.assertTrue(sync2._send_tips.call_count, 16)
 
+    def test_sync_rate_limiter_disconnect(self):
+        # Test send_tips delayed calls cancelation with disconnection
+        manager1 = self.create_peer()
+        manager2 = self.create_peer()
+        manager2.connections.MAX_ENABLED_SYNC = 0
+
+        conn12 = FakeConnection(manager1, manager2, latency=0.05)
+        self.simulator.add_connection(conn12)
+        self.simulator.run(3600)
+
+        connections = manager2.connections
+        connections.rate_limiter.reset(connections.GlobalRateLimiter.SEND_TIPS)
+        connections.enable_rate_limiter(1, 1)
+
+        connected_peers2 = list(manager2.connections.connected_peers.values())
+        self.assertEqual(1, len(connected_peers2))
+
+        protocol1 = connected_peers2[0]
+        sync1 = protocol1.state.sync_manager
+        sync1._send_tips = Mock(wraps=sync1._send_tips)
+
+        sync1.send_tips()
+        self.assertEqual(sync1._send_tips.call_count, 1)
+        self.assertEqual(len(sync1._send_tips_call_later), 0)
+
+        sync1.send_tips()
+        self.assertEqual(sync1._send_tips.call_count, 1)
+        self.assertEqual(len(sync1._send_tips_call_later), 1)
+
+        sync1.send_tips()
+        self.assertEqual(sync1._send_tips.call_count, 1)
+        self.assertEqual(len(sync1._send_tips_call_later), 2)
+
+        # Close the connection.
+        conn12.disconnect(Failure(Exception('testing')))
+        self.simulator.remove_connection(conn12)
+
+        self.simulator.run(30)
+
+        # Send tips should not be called any further since the connection has already been closed.
+        self.assertEqual(sync1._send_tips.call_count, 1)
+        # Residual delayed calls
+        self.assertEqual(len(sync1._send_tips_call_later), 2)
+        # The residual delayed calls should have been canceled
+        for call_later in sync1._send_tips_call_later:
+            self.assertFalse(call_later.active())
+
+    def test_sync_rate_limiter_delayed_calls_draining(self):
+        # Test the draining of delayed calls from _send_tips_call_later list
+        manager1 = self.create_peer()
+        manager2 = self.create_peer()
+        manager2.connections.MAX_ENABLED_SYNC = 0
+
+        conn12 = FakeConnection(manager1, manager2, latency=0.05)
+        self.simulator.add_connection(conn12)
+        self.simulator.run(3600)
+
+        connections = manager2.connections
+        connections.rate_limiter.reset(connections.GlobalRateLimiter.SEND_TIPS)
+        connections.enable_rate_limiter(1, 1)
+
+        connected_peers2 = list(manager2.connections.connected_peers.values())
+        self.assertEqual(1, len(connected_peers2))
+
+        protocol1 = connected_peers2[0]
+        sync1 = protocol1.state.sync_manager
+
+        sync1.send_tips()
+        self.assertEqual(len(sync1._send_tips_call_later), 0)
+
+        sync1.send_tips()
+        self.assertEqual(len(sync1._send_tips_call_later), 1)
+
+        sync1.send_tips()
+        self.assertEqual(len(sync1._send_tips_call_later), 2)
+
+        sync1.send_tips()
+        self.assertEqual(len(sync1._send_tips_call_later), 3)
+
+        self.simulator.run(30)
+
+        # Without disconnection, all the delayed calls
+        # should have been executed
+        self.assertEqual(len(sync1._send_tips_call_later), 0)
+
 
 class SyncV1RandomSimulatorTestCase(unittest.SyncV1Params, BaseRandomSimulatorTestCase):
     __test__ = True