diff --git a/Pipfile b/Pipfile
index 23e513e..b10ba1e 100644
--- a/Pipfile
+++ b/Pipfile
@@ -7,7 +7,6 @@ name = "pypi"
 numpy = "*"
 scipy = "*"
 biopython = "*"
-joblib = "*"
 pysam = "*"
 requests = "*"
 urllib3 = ">=1.26.5"
diff --git a/Pipfile.lock b/Pipfile.lock
index 131292c..07e8e12 100644
--- a/Pipfile.lock
+++ b/Pipfile.lock
@@ -1,7 +1,7 @@
 {
     "_meta": {
         "hash": {
-            "sha256": "caa348757d63e3af7628f055eb7f62e2942079b85a3dd3fdbbd8542f9603dcd4"
+            "sha256": "64c2c83d4c2bfe09b4794811206eed04b5e1a8a1692f76be6817380f26fb4a9a"
         },
         "pipfile-spec": 6,
         "requires": {},
@@ -161,15 +161,6 @@
             "markers": "python_version >= '3.5'",
             "version": "==3.4"
         },
-        "joblib": {
-            "hashes": [
-                "sha256:92f865e621e17784e7955080b6d042489e3b8e294949cc44c6eac304f59772b1",
-                "sha256:ef4331c65f239985f3f2220ecc87db222f08fd22097a3dd5698f693875f8cbb9"
-            ],
-            "index": "pypi",
-            "markers": "python_version >= '3.7'",
-            "version": "==1.3.2"
-        },
         "numpy": {
             "hashes": [
                 "sha256:06fa1ed84aa60ea6ef9f91ba57b5ed963c3729534e6e54055fc151fad0423f0a",
diff --git a/doc/iss/install.rst b/doc/iss/install.rst
index 83e835d..a80dd58 100644
--- a/doc/iss/install.rst
+++ b/doc/iss/install.rst
@@ -18,7 +18,6 @@ To install InSilicoSeq, type the following in your terminal:
 It will install InSilicoSeq as well as the following dependencies:
 
 * biopython
-* joblib
 * numpy
 * pysam
 * scipy
diff --git a/setup.py b/setup.py
index e84d4c0..6dec9ee 100644
--- a/setup.py
+++ b/setup.py
@@ -23,7 +23,7 @@
     license="MIT",
     packages=find_packages(),
     tests_require=["pytest"],
-    install_requires=["numpy", "scipy", "biopython>=1.79", "pysam>=0.15.1", "joblib", "requests"],
+    install_requires=["numpy", "scipy", "biopython>=1.79", "pysam>=0.15.1", "requests"],
     include_package_data=True,
     entry_points={
         "console_scripts": ["iss = iss.app:main"],