diff --git a/docs/changelog.rst b/docs/changelog.rst
index 1ba2d1d548..7bd3fa1a3b 100644
--- a/docs/changelog.rst
+++ b/docs/changelog.rst
@@ -27,6 +27,7 @@ In preparation for HD Views developments (PR #3298)
 
 - Recreate cache folders if missing. (#3384)
 - Modify site's geometry before saving to avoid edition and export of shapefiles (#3399)
+- Fix API V2 cache key with X-Forwarded-Proto header (#3404)
 
 
 2.94.0     (2022-12-12)
diff --git a/geotrek/api/tests/test_v2.py b/geotrek/api/tests/test_v2.py
index 544a37e7bc..b715ce3f72 100644
--- a/geotrek/api/tests/test_v2.py
+++ b/geotrek/api/tests/test_v2.py
@@ -13,6 +13,7 @@
 from django.utils import timezone
 from freezegun.api import freeze_time
 from mapentity.tests.factories import SuperUserFactory
+from rest_framework.test import APITestCase
 
 from geotrek import __version__
 from geotrek.authent import models as authent_models
@@ -38,6 +39,7 @@
 from geotrek.tourism.tests import factories as tourism_factory
 from geotrek.trekking import models as trek_models
 from geotrek.trekking.tests import factories as trek_factory
+from geotrek.trekking.tests.factories import PracticeFactory
 from geotrek.zoning import models as zoning_models
 from geotrek.zoning.tests import factories as zoning_factory
 
@@ -4255,3 +4257,41 @@ def test_cache_is_used_when_getting_trek_profile_svg(self):
             response = self.client.get(reverse('apiv2:trek-profile', args=(self.trek.pk,)), {"format": "svg"})
         self.assertEqual(response.status_code, 200)
         self.assertIn('image/svg+xml', response['Content-Type'])
+
+
+class GenericCacheTestCase(APITestCase):
+    @classmethod
+    def setUpTestData(cls):
+        cls.practice = PracticeFactory.create()
+
+    def test_cache_invalidates_along_x_forwarded_proto_header(self):
+        with self.assertNumQueries(2):
+            response = self.client.get(reverse('apiv2:practice-detail', args=(self.practice.pk,)))
+        data = response.json()
+        self.assertTrue(data['pictogram'].startswith('http://'))
+
+        # after cache hit, query number is 1
+        with self.assertNumQueries(1):
+            response = self.client.get(reverse('apiv2:practice-detail', args=(self.practice.pk,)))
+        data = response.json()
+        self.assertTrue(data['pictogram'].startswith('http://'))
+
+        # we used custom header, cache is invalidate and url is now https
+        with self.assertNumQueries(2):
+            response = self.client.get(reverse('apiv2:practice-detail', args=(self.practice.pk,)),
+                                       HTTP_X_FORWARDED_PROTO='https')
+        data = response.json()
+        self.assertTrue(data['pictogram'].startswith('https://'))
+
+        # cache is hit
+        with self.assertNumQueries(1):
+            response = self.client.get(reverse('apiv2:practice-detail', args=(self.practice.pk,)),
+                                       HTTP_X_FORWARDED_PROTO='https')
+        data = response.json()
+        self.assertTrue(data['pictogram'].startswith('https://'))
+
+        # first request is always cached
+        with self.assertNumQueries(1):
+            response = self.client.get(reverse('apiv2:practice-detail', args=(self.practice.pk,)))
+        data = response.json()
+        self.assertTrue(data['pictogram'].startswith('http://'))
diff --git a/geotrek/api/v2/viewsets.py b/geotrek/api/v2/viewsets.py
index 7f897a347a..2f43c4205c 100644
--- a/geotrek/api/v2/viewsets.py
+++ b/geotrek/api/v2/viewsets.py
@@ -33,7 +33,8 @@ def get_ordered_query_params(self):
 
     def get_base_cache_string(self):
         """ return cache string as url path + ordered query params """
-        return f"{self.request.path}:{self.get_ordered_query_params()}:{self.request.accepted_renderer.format}"
+        proto_scheme = self.request.headers.get('X-Forwarded-Proto', self.request.scheme)  # take care about scheme defined in nginx.conf
+        return f"{self.request.path}:{self.get_ordered_query_params()}:{self.request.accepted_renderer.format}:{proto_scheme}"
 
     def get_object_cache_key(self, pk):
         """ return specific object cache key based on object date_update column"""