diff --git a/scripts/jest/devtools/config.build-devtools-regression.js b/scripts/jest/devtools/config.build-devtools-regression.js
index 672cb98258fde..2b8b650173c1e 100644
--- a/scripts/jest/devtools/config.build-devtools-regression.js
+++ b/scripts/jest/devtools/config.build-devtools-regression.js
@@ -31,6 +31,8 @@ if (REACT_VERSION) {
       '^react-dom/client$'
     ] = `<rootDir>/build/${NODE_MODULES_DIR}/react-dom`;
   }
+
+  setupFiles.push(require.resolve('./setupTests.build-devtools-regression'));
 }
 
 module.exports = {
diff --git a/scripts/jest/devtools/setupTests.build-devtools-regression.js b/scripts/jest/devtools/setupTests.build-devtools-regression.js
new file mode 100644
index 0000000000000..a1221d53d2fa6
--- /dev/null
+++ b/scripts/jest/devtools/setupTests.build-devtools-regression.js
@@ -0,0 +1,7 @@
+'use strict';
+
+// Regression tests use a React DOM profiling, so we need
+// to replace these tests with scheduler/tracing-profiling
+jest.mock('scheduler/tracing', () => {
+  return jest.requireActual('scheduler/tracing-profiling');
+});